CVPR 2026 论文列表

Conference on Computer Vision and Pattern Recognition

录用类型

4,042篇论文

按官方录用论文列表统计,可能与会议公布的数字略有出入。

  • Oral
    1383.4%
  • Poster
    3,90496.6%

浏览全部论文

主题: 扩散模型 · 607 篇论文 · 重置筛选

NEC-Diff: Noise-Robust Event-RAW Complementary Diffusion for Seeing Motion in Extreme Darkness

Haoyue Liu, Jinghan Xu, Luxin Feng, Hanyu Zhou, Haozhi Zhao, Yi Chang, Luxin Yan

展开摘要

High-quality imaging of dynamic scenes in extremely low-light conditions is highly challenging. Photon scarcity induces severe noise and texture loss, causing significant image degradation. Event cameras, featuring a high dynamic range (120 dB) and high sensitivity to motion, serve as powerful complements to conventional cameras by offering crucial cues for preserving subtle textures. However, most existing approaches emphasize texture recovery from events, while paying little attention to image noise or the intrinsic noise of events themselves, which ultimately hinders accurate pixel reconstruction under photon-starved conditions. In this work, we propose NEC-Diff, a novel diffusion-based event-RAW hybrid imaging framework that extracts reliable information from heavily noisy signals to reconstruct fine scene structures. The framework is driven by two key insights: (1) combining the linear light-response property of RAW images with the brightness-change nature of events to establish a physics-driven constraint for robust dual-modal denoising; and (2) dynamically estimating the SNR of both modalities based on denoising results to guide adaptive feature fusion, thereby injecting reliable cues into the diffusion process for high-fidelity visual reconstruction. Furthermore, we construct the REAL (Raw and Event Acquired in Low-light) dataset which provides 47,800 pixel-aligned low-light RAW images, events, and high-quality references under 0.001-0.8 lux illumination. Extensive experiments demonstrate the superiority of NEC-Diff under extreme darkness.

Poster
MAD: Motion Appearance Decoupling for efficient Driving World Models

Ahmad Rahimi, Valentin Gerard, Eloi Zablocki, Matthieu Cord, Alexandre Alahi

展开摘要

Recent video diffusion models generate photorealistic, temporally coherent videos, yet they fall short as reliable world models for autonomous driving, where structured motion and physically consistent interactions are essential. Adapting these generalist video models to driving domains has shown promise but typically requires massive domain-specific data and costly fine-tuning. We propose an efficient adaptation framework that converts generalist video diffusion models into controllable driving world models with minimal supervision. The key idea is to decouple motion learning from appearance synthesis. First, the model is adapted to predict structured motion in a simplified form: videos of skeletonized agents and scene elements, focusing learning on physical and social plausibility. Then, the same backbone is reused to synthesize realistic RGB videos conditioned on these motion sequences, effectively "dressing" the motion with texture and lighting. This two-stage process mirrors a reasoning-rendering paradigm: first infer dynamics, then render appearance. Our experiments show this decoupled approach is exceptionally efficient: adapting SVD, we match prior SOTA models with less than 6% of their compute. Scaling to LTX, our MAD-LTX model outperforms all open-source competitors, and supports a comprehensive suite of text, ego, and object controls. Project page: \href https://vita-epfl.github.io/MAD-World-Model/ https://vita-epfl.github.io/MAD-World-Model/

Poster
OpenDPR: Open-Vocabulary Change Detection via Vision-Centric Diffusion-Guided Prototype Retrieval for Remote Sensing Imagery

Qi Guo, Jue Wang, Yinhe Liu, Yanfei Zhong

展开摘要

Open-vocabulary change detection (OVCD) seeks to recognize arbitrary changes of interest by enabling generalization beyond a fixed set of predefined classes. We reformulate OVCD as a two-stage pipeline: first generate class-agnostic change proposals using visual foundation models (VFMs) such as SAM and DINOv2, and then perform category identification with vision-language models (VLMs) such as CLIP. We reveal that category identification errors are the primary bottleneck of OVCD, mainly due to the limited ability of VLMs based on image-text matching to represent fine-grained land-cover categories. To address this, we propose OpenDPR, a training-free vision-centric diffusion-guided prototype retrieval framework. OpenDPR leverages diffusion models to construct diverse prototypes for target categories offline, and to perform similarity retrieval with change proposals in the visual space during inference. The secondary bottleneck lies in change localization, due to the inherent lack of change priors in VFMs. To bridge this gap, we design a spatial-to-change weakly supervised change detection module named S2C to adapt their strong spatial modeling capabilities for change localization. Integrating the pretrained S2C into OpenDPR leads to an optional weakly supervised variant named OpenDPR-W, which further improves OVCD with minimal supervision. Experimental results on four benchmark datasets demonstrate that the proposed methods achieve state-of-the-art performance under both supervision modes. Code is available at https://github.com/guoqi2002/OpenDPR.

Poster
RecTok: Reconstruction Distillation along Rectified Flow

Qingyu Shi, Size Wu, Jinbin Bai, Kaidong Yu, Yujing Wang, Yunhai Tong, Xiangtai Li, Xuelong Li

展开摘要

Visual tokenizers play a crucial role in diffusion models. The dimensionality of latent space governs both reconstruction fidelity and the semantic expressiveness of the latent feature. However, a fundamental trade-off is inherent between dimensionality and generation quality, constraining existing methods to low-dimensional latent spaces. Although recent works have leveraged vision foundation models (VFMs) to enrich the semantics of visual tokenizers and accelerate convergence, high-dimensional tokenizers still underperform their low-dimensional counterparts. In this work, we propose RecTok, which overcomes the limitations of high-dimensional visual tokenizers through two key innovations: flow semantic distillation and reconstruction-alignment distillation. Our key insight is to make the forward flow in flow matching semantically rich, which serves as the training space of diffusion transformers, rather than focusing on the latent space as in previous works. Specifically, our method distill the semantic information in VFMs into the forward flow trajectories in flow matching. And we further enhance the semantics by introducing a masked feature reconstruction loss. Our RecTok achieves superior image reconstruction, generation quality, and discriminative performance. It achieves state-of-the-art results on the gFID-50K under both with and without classifier-free guidance settings, while maintaining a semantically rich latent space structure. Furthermore, as the latent dimensionality increases, we observe consistent improvements. Code and model will be publicly available.

Poster
MaskDiME: Adaptive Masked Diffusion for Precise and Efficient Visual Counterfactual Explanations

Changlu Guo, Anders Nymark Christensen, Anders Bjorholm Dahl, Morten Rieger Hannemose

展开摘要

Visual counterfactual explanations aim to reveal the minimal semantic modifications that can alter a model's prediction, providing causal and interpretable insights into deep neural networks. However, existing diffusion-based counterfactual generation methods are often computationally expensive, slow to sample, and imprecise in localizing the modified regions. To address these limitations, we propose MaskDiME, a simple, fast, yet effective diffusion framework that unifies semantic consistency and spatial precision through localized sampling. Our approach adaptively focuses on decision-relevant regions to achieve localized and semantically consistent counterfactual generation while preserving high image fidelity. Our training-free framework, MaskDiME, performs inference over 30x faster than the baseline and achieves comparable or state-of-the-art performance across five benchmark datasets spanning diverse visual domains, establishing a practical and generalizable solution for efficient counterfactual explanation. Our code is available at https://github.com/clguo/MaskDiME.

Poster
Bidirectional Normalizing Flow: From Data to Noise and Back

Yiyang Lu, Qiao Sun, Xianbang Wang, Zhicheng Jiang, Hanhong Zhao, Kaiming He

展开摘要

Normalizing Flows (NFs) have been established as a principled framework for generative modeling. Standard NFs consist of a forward process and a reverse process: the forward process maps data to noise, while the reverse process generates samples by inverting it. Typical NF forward transformations are constrained by explicit invertibility, ensuring that the reverse process can serve as their exact analytic inverse. Recent developments in TARFlow and its variants have revitalized NF methods by combining Transformers and autoregressive flows, but have also exposed causal decoding as a major bottleneck. In this work, we introduce Bidirectional Normalizing Flow (BiFlow), a framework that removes the need for an exact analytic inverse. BiFlow learns a reverse model that approximates the underlying noise-to-data inverse mapping, enabling more flexible loss functions and architectures. Experiments on ImageNet demonstrate that BiFlow, compared to its causal decoding counterpart, improves generation quality while accelerating sampling by up to two orders of magnitude. BiFlow yields state-of-the-art results among NF-based methods and competitive performance among single-evaluation ("1-NFE") methods. Following recent encouraging progress on NFs, we hope our work will draw further attention to this classical paradigm.

Poster
Circuit Mechanisms for Spatial Relation Generation in Diffusion Transformers

Binxu Wang, Jingxuan Fan, Xu Pan

展开摘要

Diffusion Transformers (DiTs) have greatly advanced text-to-image generation, but models still struggle to generate the correct spatial relations between objects as specified in the text prompt. In this study, we adopt a mechanistic interpretability approach to investigate how a DiT can generate correct spatial relations between objects. We train, from scratch, DiTs of different sizes with different text encoders to learn to generate images containing two objects whose attributes and spatial relations are specified in the text prompt. We find that, although all the models can learn this task to near-perfect accuracy, the underlying mechanisms differ drastically depending on the choice of text encoder. When using random text embeddings, we find that the spatial-relation information is passed to image tokens through a two-stage circuit, involving two cross-attention heads that separately read the spatial relation and single-object attributes in the text prompt. When using a pretrained text encoder (T5), we find that the DiT uses a different circuit that leverages information fusion in the text tokens, reading spatial-relation and single-object information together from a single text token. We further show that, although the in-domain performance is similar for the two settings, their robustness to out-of-domain perturbations differs, potentially suggesting the difficulty of generating correct relations in real-world scenarios.

Poster
CRAFT: Aligning Diffusion Models with Fine-Tuning Is Easier Than You Think

Zening Sun, Zhengpeng Xie, Lichen Bai, Shitong Shao, Shuo Yang, Zeke Xie

展开摘要

Aligning Diffusion models has achieved remarkable breakthroughs in generating high-quality, human preference-aligned images. Existing techniques, such as supervised fine-tuning (SFT) and DPO-style preference optimization, have become principled tools for fine-tuning diffusion models. However, SFT relies on high-quality images that are costly to obtain, while DPO-style methods depend on large-scale preference datasets, which are often inconsistent in quality. Beyond data dependency, these methods are further constrained by computational inefficiency. To address these two challenges, we propose Composite Reward Assisted Fine-Tuning (CRAFT), a lightweight yet powerful fine-tuning paradigm that requires significantly reduced training data while maintaining computational efficiency. It first leverages a Composite Reward Filtering (CRF) technique to construct a high-quality and consistent training dataset and then perform an enhanced variant of SFT. We also theoretically prove that CRAFT actually optimizes the lower bound of group-based reinforcement learning, establishing a principled connection between SFT with selected data and reinforcement learning. Our extensive empirical results demonstrate that CRAFT with only 100 samples can easily outperform recent SOTA preference optimization methods with thousands of preference-paired samples. Moreover, CRAFT can even achieve 11-220xfaster convergences than the baseline preference optimization methods, highlighting its extremely high efficiency.

Poster
Grounded Latents for Entity-Centric 4D Scene Generation

Jinhyung Park, Navyata Sanghvi, Erica Weng, Shawn Hunt, Shinya Tanaka, Hironobu Fujiyoshi, Kris Kitani

展开摘要

Although recent work has explored generative modeling of 3D or 4D driving scenes, most approaches operate on dense voxel-based representations, which are computationally expensive and struggle to maintain temporal or structural consistency. These methods often produce blurred or merged entities (i.e., cars, trucks, pedestrians) and lack fine-grained control over individual scene elements. We propose LatentWorld, a framework for generative modeling in a compact, entity-centric latent space, where each grounded 3D latent represents a semantically meaningful local region of the scene. This formulation enables precise, consistent control of both foreground and background elements while preserving geometric detail. We further extend this representation to 4D by learning a motion diffusion model for both ego and dynamic actors, conditioned on the generated 3D scene, and by propagating the grounded latents through time. Our framework produces physically consistent and temporally coherent 4D scenes, supporting controllable and realistic generation.

Poster
Latent Diffusion Inversion Requires Understanding the Latent Space

Mingxing Rao, Bowen Qu, Daniel Moyer

展开摘要

The recovery of training data from generative models ("model inversion") has been extensively studied for diffusion models in the data domain as a memorization/overfitting phenomenon. Latent diffusion models (LDMs), which operate on the latent codes from encoder/decoder pairs, have been robust to prior inversion methods. In this work we describe two key findings: (1) the diffusion model exhibits non-uniform memorization across latent codes, tending to overfit samples located in high-distortion regions of the decoder pullback metric; (2) even within a single latent code, memorization contributions are unequal across representation dimensions. Our proposed method to ranks latent dimensions by their contribution to the decoder pullback metric, which in turn identifies dimensions that contribute to memorization. For score-based membership inference, a sub-task of model inversion, we find that removing less-memorizing dimensions improves performance on all tested methods and datasets, with average AUROC gains of 1-4% and substantial increases in TPR@1%FPR (1-32%) across diverse datasets including CIFAR-10, CelebA, ImageNet-1K, Pokemon, MS-COCO, and Flickr. Our results highlight the overlooked influence of the auto-encoder geometry on LDM memorization and provide a new perspective for analyzing privacy risks in diffusion-based generative models.

Poster
2ndMatch: Finetuning Pruned Diffusion Models via Second-Order Jacobian Matching

Caleb Zheng, Eli Shlizerman

展开摘要

Diffusion models achieve remarkable performance across diverse generative tasks in computer vision, but their high computational cost remains a major barrier to deployment. Model pruning offers a promising way to reduce inference cost and enable lightweight models. However, pruning leads to quality drop due to reduced capacity. A key limitation of existing pruning approaches is that pruned models are finetuned using the same objective as the dense model (denoising score matching). Since the dense model is accessible during finetuning, it warrants a more effective approach for knowledge transfer from the dense to the pruned model. Motivated by this, we propose 2ndMatch(2ndM), a general-purpose finetuning framework that introduces a 2nd-order Jacobian (J^ \top J) Matching loss inspired by Finite-Time Lyapunov Exponents. 2ndM teaches the pruned model to mimic the sensitivity of the dense teacher, i.e., how to respond to small perturbations over time, through scalable random projections. The framework is architecture-agnostic and applies to both U-Net- and Transformer-based diffusion models. Experiments on CIFAR-10, CelebA, LSUN, ImageNet, and MSCOCO demonstrate that 2ndM reduces the performance gap between pruned and dense models, substantially improving output quality.

Poster
Decoupled Residual Denoising Diffusion Models for Unified and Data Efficient Image-to-Image Translation

Ziyue Lin, Jiahe Hou, Hongyu Xia, Xinrui Xie, Feifei Wang, Yuyin Zhou, Wei Wang, Jiawei Liu, Liangqiong Qu

展开摘要

We propose Decoupled Residual Denoising Diffusion models (DRDD) for unified and data-efficient image-to-image (I2I) translation. While diffusion models have advanced I2I translation in terms of quality and diversity, we uncover a previously under-explored property in diffusion models. Crucially, beyond its conventional role of manifold lifting (i.e., moving data off low-dimensional manifolds), injecting Gaussian noise facilitates domain harmonization by implicitly aligning feature distributions across domains, a property particularly advantageous for unified I2I translation. However, existing diffusion models prematurely erode this harmonization effect, as noise and residuals are simultaneously removed in a single coupled diffusion process. To address this, DRDD decouples the diffusion process into two sequential and independent diffusion stages: (1) a stochastic noise diffusion for domain harmonization and manifold lifting, and (2) a deterministic residual diffusion that learns the core semantic mapping entirely within the fixed-noise domain. This decoupling preserves harmonization and manifold lifting effects throughout the transformation, substantially simplifying the learning of unified mappings across diverse tasks and domains. Notably, the noise diffusion stage is trained exclusively on abundant, unpaired target-domain images, greatly improving data efficiency. Comprehensive theoretical and empirical analysis demonstrates that DRDD is broadly compatible with mainstream diffusion models and consistently delivers robust, unified I2I translation, even under limited paired data. Our code is available at https://github.com/HKU-HealthAI/DRDD.

Poster
PG-VTON: Single-Pass Training-Free Virtual Try-On via Patch-Guided Reference Alignment

Guohao Zhao, Yuxin Peng

展开摘要

Virtual try-on (VTON) aims to render a target garment onto a person while preserving pose, identity, and fine-grained appearance. Most existing methods rely on supervised paired data, limiting cross-domain generalization, while recent training-free approaches, though more robust, require multiple diffusion calls and complex compositing, making deployment impractical. We propose PG-VTON, a single-pass, training-free framework based on Patch-Guided Reference Alignment. Our key insight is that modern inpainting diffusion models already possess strong in-context completion: given a masked person and a small garment patch, they can synthesize plausible, pose-consistent clothing without task-specific training. PG-VTON exploits this capability with two lightweight components: Patch-Anchored Identity Priming (PIP) injects a localized garment patch only in early denoising steps to anchor garment identity, and Reference-Aware Attention (RAA) strengthens attention from masked-region tokens to garment tokens to enhance detail transfer, all without modifying model weights. With a single diffusion pass, PG-VTON achieves state-of-the-art performance among training-free methods on DressCode and VITON-HD and generalizes effectively to subject insertion. Code is available at \href https://github.com/PKU-ICST-MIPL/PG-VTON_CVPR2026 https://github.com/PKU-ICST-MIPL/PG-VTON_CVPR2026 .

Poster
IMS3: Breaking Distributional Aggregation in Diffusion-Based Dataset Distillation

Chenru Wang, Yunyi Chen, Zijun Yang, Joey Tianyi Zhou, Chi Zhang

展开摘要

Dataset Distillation aims to synthesize compact datasets that can approximate the training efficacy of large-scale real datasets, offering an efficient solution to the increasing computational demands of modern deep learning. Recently, diffusion-based dataset distillation methods have shown great promise by leveraging the strong generative capacity of diffusion models to produce diverse and structurally consistent samples. However, a fundamental goal misalignment persists: diffusion models are optimized for generative likelihood rather than discriminative utility, resulting in over-concentration in high-density regions and inadequate coverage of boundary samples crucial for classification. To address this issue, we propose two complementary strategies. Inversion-Matching (IM) introduces an inversion-guided fine-tuning process that aligns denoising trajectories with their inversion counterparts, broadening distributional coverage and enhancing diversity. Selective Subgroup Sampling( S^3 ) is a training-free sampling mechanism that improves inter-class separability by selecting synthetic subsets that are both representative and distinctive. Extensive experiments demonstrate that our approach significantly enhances the discriminative quality and generalization of distilled datasets, achieving state-of-the-art performance among diffusion-based methods.

Poster
Lighting-grounded Video Generation with Renderer-based Agent Reasoning

Ziqi Cai, Taoyu Yang, Zheng Chang, Si Li, Han Jiang, Shuchen Weng, Boxin Shi

展开摘要

Diffusion models have achieved remarkable progress in video generation, but their controllability remains a major limitation. Key scene factors such as layout, lighting, and camera trajectory are often entangled or only weakly modeled, restricting their applicability in domains like filmmaking and virtual production where explicit scene control is essential. We present LiVER, a diffusion-based framework for scene-controllable video generation. To achieve this, we introduce a novel framework that conditions video synthesis on explicit 3D scene properties, supported by a new large-scale dataset with dense annotations of object layout, lighting, and camera parameters. Our method disentangles these properties by rendering control signals from a unified 3D representation. We propose a lightweight conditioning module and a progressive training strategy to integrate these signals into a foundational video diffusion model, ensuring stable convergence and high fidelity. Our framework enables a wide range of applications, including image-to-video and video-to-video synthesis where the underlying 3D scene is fully editable. To further enhance usability, we develop a scene agent that automatically translates high-level user instructions into the required 3D control signals. Experiments show that LiVER achieves state-of-the-art photorealism and temporal consistency while enabling precise, disentangled control over scene factors, setting a new standard for controllable video generation.

Poster
Guiding Diffusion Models with Fine-Grained Conditions and Semantics-Preserving Sampling for One-Shot Federated Learning

Xiaojun Deng, Tianchi Liao, Zhiyuan Liu, Chuan Chen, Zibin Zheng

展开摘要

One-shot Federated Learning (OSFL) has emerged as a promising paradigm to mitigate the high communication overhead of traditional federated learning. However, its effectiveness is often hindered by data heterogeneity across clients. While recent methods leverage pre-trained diffusion models to generate data for OSFL, they often struggle with some practical limitations, including a lack of semantic fidelity in capturing the fine-grained characteristics of local data, and insufficient diversity in the generated data, which collectively degrade the performance of the global model. To address these challenges, we propose Espresso, a novel framework that enhances both the fidelity and diversity of synthetic data in OSFL. Espresso consists of two main components: (1) Fine-Grained Condition Learning, which learns fine-grained conditional embeddings to improve semantic fidelity and diversity by modeling intra-category patterns, and (2) Semantics-Preserving Sampling, which diversifies the generated data by modeling the distribution of latent noises and applying a self-reflection sampling strategy. Extensive experiments on benchmark datasets demonstrate that Espresso can improve the semantic fidelity and diversity of the synthetic data, leading to an enhancement in the performance of the global model compared to state-of-the-art OSFL methods under data heterogeneity.

Poster
Reward Forcing: Efficient Streaming Video Generation with Rewarded Distribution Matching Distillation

Yunhong Lu, Yanhong Zeng, Haobo Li, Hao OUYANG, Qiuyu Wang, Ka Leong Cheng, Jiapeng Zhu, Hengyuan Cao, Zhipeng Zhang, Xing Zhu, Yujun Shen, Min Zhang

展开摘要

Efficient streaming video generation is critical for simulating interactive and dynamic worlds. Existing methods distill few-step video diffusion models with sliding window attention, using initial frames as sink tokens to maintain attention performance and reduce error accumulation. However, video frames become overly dependent on these static tokens, resulting in copied initial frames and diminished motion dynamics. To address this, we introduce Reward Forcing, a novel framework with two key designs. First, we propose EMA-Sink, which maintains fixed-size tokens initialized from initial frames and continuously updated by fusing evicted tokens via exponential moving average as they exit the sliding window. Without additional computation cost, EMA-Sink tokens capture both long-term context and recent dynamics, preventing initial frame copying while maintaining long-horizon consistency. Second, to better distill motion dynamics from teacher models, we propose a novel Rewarded Distribution Matching Distillation (Re-DMD). Vanilla distribution matching treats every training sample equally, limiting the model's ability to prioritize dynamic content. Instead, Re-DMD biases the model's output distribution toward high-reward regions by prioritizing samples with greater dynamics rated by a vision-language model. Re-DMD significantly enhances motion quality while preserving data fidelity. We include both quantitative and qualitative experiments to show that Reward Forcing achieves state-of-the-art performance on standard benchmarks while enabling high-quality streaming video generation at 23.1 FPS on a single H100 GPU.

Poster
Region-Adaptive Sampling for Diffusion Transformers

Ziming Liu, Yifan Yang, Chengruidong Zhang, Yiqi Zhang, Lili Qiu, Yang You, Yuqing Yang

展开摘要

Diffusion models (DMs) have become the state-of-the-art for generative tasks across domains, but their reliance on sequential forward passes limits real-time performance. Prior acceleration methods mainly reduce sampling steps or reuse intermediate results. Leveraging the flexibility of Diffusion Transformers (DiTs) to handle variable token counts, we propose RAS, a training-free sampling strategy that dynamically assigns different update ratios to image regions based on model focus. Our key observation is that at each step, DiTs concentrate on semantically meaningful areas, and these regions exhibit strong continuity across consecutive steps. Exploiting this, RAS updates only focused regions while reusing cached noise for others, with focus determined from the previous step's output. Evaluated on Stable Diffusion 3 and Lumina-Next-T2I, RAS achieves up to 2.36x and 2.51x speedups, respectively, with minimal quality loss. This demonstrates a practical step toward more efficient diffusion transformers for real-time generation.

Poster
RADAR: VQ-VAE Decoder of VAR is a Good Student for Restoring Against Degradation by Acceleration

Ziyang Wang, Yue Zhang, Mingdao Wang, Yasen Zhang, Teer Song, Yu Tian, Xueming Li

展开摘要

Visual Autoregressive Modeling (VAR) has recently emerged as a powerful paradigm for image generation that surpasses diffusion models in efficiency and quality. However, accelerating attention computation in VAR is still challenging because attention patterns across scales exhibit strong and complex semantic biases that early coarse-scale tokens dominate global structure, while fine-scale tokens mainly refine local details. Existing acceleration methods rely on heuristic token pruning or fixed attention masks, lacking a principled way to balance acceleration and semantic fidelity. In this work, we propose a two-stage acceleration framework for VAR. First, we introduce a semantic-cost-aware masking strategy (SCA-Mask) that quantifies the importance of each attention tile and formulates mask shape design as a cost-constrained optimization problem. This enables adaptive pruning under a given compute budget while preserving essential semantic context. Second, we present Post-Acceleration Adaptation (PAA), a decoder-side fine-tuning scheme that employs internal knowledge distillation to restore image quality from pruned latents. PAA does not require external data and uses a lightweight LoRA-based adaptation, providing a highly efficient alternative to retraining the autoregressive transformer. Comprehensive experiments across multiple VAR tasks demonstrate that our method achieves decent speedup with negligible loss of visual fidelity, yielding a principled and effective pathway toward fast and high-quality visual autoregressive generation.

Poster
MMCP-GEN: A Modality-Extensible Diffusion Language Model for Conditional Protein Sequence Generation

Zeyu An, Wanyu Lin, Feng Tan, Shujun Wang

展开摘要

Recent advances in diffusion-based language models (DLMs) have shown remarkable potential for de novo protein design. However, enabling controllable protein generation requires integrating diverse biological conditions, such as structure, functions, and chemical interactions, each represented in distinct modalities. Existing approaches often either support a single condition or treat multiple conditions through separate modality-specific encoders. This isolation limits cross-modal interaction, reduces generation quality, and complicates the incorporation of new conditions without retraining or redesigning the backbone. To address these limitations, we introduce MMCP-GEN, a DLM for Multi-Modal, Multi-Condition Protein sequence GENeration. MMCP-GEN establishes a new paradigm for controllable protein generation under complex multimodal constraints. Its core is a modality-composable and extensible conditioning mechanism that fuses heterogeneous biological conditions via learnable queries and modality-indicator heads, enabling disentangled, extensible, and cross-modal condition integration without retraining the backbone. A joint generation-and-scoring objective further aligns sequence recovery with structural fidelity. Empirically, MMCP-GEN achieves state-of-the-art performance across structure-, function-, and ligand-conditioned tasks, improving sequence recovery by up to 5% and outperforming attentive baselines in diverse functional annotation tasks. These results establish MMCP-GEN as a general and high-fidelity framework for controllable protein generation. The source code is publicly available at https://github.com/WanyuGroup.

Poster