ICLR 2026 论文列表

International Conference on Learning Representations

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5,358篇论文

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    2244.2%
  • Poster
    5,13495.8%

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主题: 应用 · computer vision · 538 篇论文 · 重置筛选

Unified Vision–Language Modeling via Concept Space Alignment

Yifu QIU, Paul-Ambroise Duquenne, Holger Schwenk

展开摘要

We introduce vSONAR, a vision–language embedding space extended from the text-only embedding space SONAR, which supports 200 text languages and 37 speech languages. To construct vSONAR, we propose a post-hoc alignment pipeline that maps the representations of an existing vision encoder into the SONAR space. We thoroughly evaluate vSONAR and show that its embeddings achieve competitive performance on text-to-video retrieval. Equipped with the SONAR text decoder, vSONAR further surpasses state-of-the-art vision–language models on video captioning tasks, including DREAM-1K (BLEU 24.3 vs. 19.6) and VATEX (BLEU 45.0 vs. 41.5). Leveraging vSONAR, we first demonstrate that the Large Concept Model (LCM) operating in SONAR and trained with English text only, can perform both single- and multi-visual concept understanding in a zero-shot manner. Finally, we introduce vLCM, which extends the LCM with vision–language instruction tuning. vLCM encodes vision and language inputs into an unified sequence of latent embeddings via vSONARand SONAR, and it is trained with the same latent diffusion objective for next-embedding prediction as in LCM's text-only pre-training. Experiments on a large-scale multilingual and -modal instruction–tuning data mixture highlight the potential of vLCM: vLCM matches state-of-the-art vision-language models on tasks covering image/video captioning and question answering, while significantly outperforming them across 61 rich- to low-resource languages out of all 62 tested languages.

Poster
IVC-Prune: Revealing the Implicit Visual Coordinates in LVLMs for Vision Token Pruning

Zhichao Sun, Yidong Ma, Gang Liu, Nemo Chen, Xu Tang, Yao Hu, Yongchao Xu

展开摘要

Large Vision-Language Models (LVLMs) achieve impressive performance across multiple tasks. A significant challenge, however, is their prohibitive inference cost when processing high-resolution visual inputs. While visual token pruning has emerged as a promising solution, existing methods that primarily focus on semantic relevance often discard tokens that are crucial for spatial reasoning. We address this gap through a novel insight into how LVLMs process spatial reasoning. Specifically, we reveal that LVLMs implicitly establish visual coordinate systems through Rotary Position Embeddings (RoPE), where specific token positions serve as implicit visual coordinates (IVC tokens) that are essential for spatial reasoning. Based on this insight, we propose IVC-Prune, a training-free, prompt-aware pruning strategy that retains both IVC tokens and semantically relevant foreground tokens. IVC tokens are identified by theoretically analyzing the mathematical properties of RoPE, targeting positions at which its rotation matrices approximate identity matrix or the $90^\circ$ rotation matrix. Foreground tokens are identified through a robust two-stage process: semantic seed discovery followed by contextual refinement via value-vector similarity. Extensive evaluations across four representative LVLMs and twenty diverse benchmarks show that IVC-Prune reduces visual tokens by approximately 50\% while maintaining $\geq$ 99\% of the original performance and even achieving improvements on several benchmarks.

Poster
ReSplat: Degradation-agnostic Feed-forward Gaussian Splatting via Self-guided Residual Diffusion

Youngho Yoon, Kuk-Jin Yoon

展开摘要

Recent advances in novel view synthesis (NVS) have predominantly focused on ideal, clear input settings, limiting their applicability in real-world environments with common degradations such as blur, low-light, haze, rain, and snow. While some approaches address NVS under specific degradation types, they are often tailored to narrow cases, lacking the generalizability needed for broader scenarios. To address this issue, we propose Restoration-based feed-forward Gaussian Splatting, named ReSplat, a novel framework capable of handling degraded multi-view inputs. Our model jointly estimates restored images and gaussians to represent the clear scene for NVS. We enable multi-view consistent universal image restoration by utilizing the 3d gaussians generated during the diffusion sampling process as self-guidance. This results in sharper and more reliable novel views. Notably, our framework adapts to various degradations without prior knowledge of their specific types. Extensive experiments demonstrate that ReSplat significantly outperforms existing methods across challenging conditions, including blur, low-light, haze, rain, and snow, delivering superior visual quality and robust NVS performance.

Poster
Prompt-Robust Vision-Language Models via Meta-Finetuning

Haohui Liang, Runlin Huang, Yingjun Du, Yujia Hu, Weifeng Su, Cees G. M. Snoek

展开摘要

Vision-language models (VLMs) have demonstrated remarkable generalization across diverse tasks by leveraging large-scale image-text pretraining. However, their performance is notoriously unstable under variations in natural language prompts, posing a considerable challenge for reliable real-world deployment. To address this prompt sensitivity, we propose Promise, a meta-learning framework for prompt-Robust vision-language models via meta-finetuning, which explicitly learns to generalize across diverse prompt formulations. Our method operates in a dual-loop meta-finetuning setting: the inner loop adapts token embeddings based on a set of varied prompts, while the outer loop optimizes for generalization on unseen prompt variants. To further improve robustness, we introduce an adaptive prompt weighting mechanism that dynamically emphasizes more generalizable prompts and a token-specific learning rate module that fine-tunes individual prompt tokens based on contextual importance. We further establish that Promise’s weighted and preconditioned inner update provably (i) yields a one-step decrease of the outer empirical risk together with a contraction of across-prompt sensitivity, and (ii) tightens a data-dependent generalization bound evaluated at the post-inner initialization. Across 15 benchmarks spanning base-to-novel generalization, cross-dataset transfer, and domain shift, our approach consistently reduces prompt sensitivity and improves performance stability over existing prompt learning methods.

Poster
Visual Prompt-Agnostic Evolution

Junze Wang, Lei Fan, Dezheng Zhang, Weipeng Jing, Donglin Di, Yang Song, Sidong Liu, Cong Cong

展开摘要

Visual Prompt Tuning (VPT) enables effective adaptation of a frozen Vision Transformer (ViT) to downstream tasks by inserting a small number of learnable prompt tokens into the token sequence at each layer. However, we observe that existing VPT variants often suffer from unstable training dynamics, characterized by gradient oscillations. A closer layer-wise analysis reveals that shallow-layer prompts tend to stagnate early, while deeper-layer prompts exhibit high-variance oscillations, leading to a cross-layer mismatch. These issues contribute to slower convergence and degraded final performance. To address these challenges, we propose the Prompt-Agnostic Evolution ($\mathtt{PAE}$) method, which can strengthen vision prompt tuning by explicitly modeling the dynamics of learnable prompts. From a frequency-domain perspective, we initialize prompts in a task-aware direction by uncovering and propagating frequency shortcut patterns that the backbone inherently exploits for recognition. To ensure coherent evolution across layers, we further employ a shared Koopman operator, which imposes a global linear transformation rather than uncoordinated, layer-specific updates. Finally, inspired by Lyapunov stability theory, we introduce a regularizer that constrains error amplification during evolution. Extensive experiments demonstrate that using $\mathtt{PAE}$ with VPT variants not only accelerates convergence with an average 1.41$\times$ speedup but also yields 1–3% gains on 25 datasets with multi downstream tasks. Beyond performance, $\mathtt{PAE}$ remains prompt-agnostic and lightweight, and it integrates seamlessly with diverse VPT variants without backbone modification or inference-time changes, providing a practical and scalable solution for advancing prompt tuning.

Poster
Deforming Videos to Masks: Flow Matching for Referring Video Segmentation

Zanyi Wang, Dengyang Jiang, Liuzhuozheng Li, Sizhe Dang, Chengzu Li, Harry Yang, Guang Dai, Mengmeng Wang, Jingdong Wang

展开摘要

Referring Video Object Segmentation (RVOS) requires segmenting specific objects in a video guided by a natural language description. The core challenge of RVOS is to anchor abstract linguistic concepts onto a specific set of pixels and continuously segment them through the complex dynamics of a video. Faced with this difficulty, prior work has often decomposed the task into a pragmatic `locate-then-segment' pipeline. However, this cascaded design creates an information bottleneck by simplifying semantics into coarse geometric prompts (e.g, point), and struggles to maintain temporal consistency as the segmenting process is often decoupled from the initial language grounding. To overcome these fundamental limitations, we propose FlowRVS, a novel framework that reconceptualizes RVOS as a conditional continuous flow problem. This allows us to harness the inherent strengths of pretrained T2V models, fine-grained pixel control, text-video semantic alignment, and temporal coherence. Instead of conventional generating from noise to mask or directly predicting mask, we reformulate the task by learning a direct, language-guided deformation from a video's holistic representation to its target mask. Our one-stage, generative approach achieves new state-of-the-art results across all major RVOS benchmarks. Specifically, achieving a J&F of 51.1 in MeViS (+1.6 over prior SOTA) and 73.3 in the zero shot Ref-DAVIS17 (+2.7), demonstrating the significant potential of modeling video understanding tasks as continuous deformation processes.

Poster
EAST: Early Action Prediction Sampling Strategy with Token Masking

Iva Sović, Ivan Martinović, Marin Oršić

展开摘要

Early action prediction seeks to anticipate an action before it fully unfolds, but limited visual evidence makes this task especially challenging. We introduce EAST, a simple and efficient framework that enables a model to reason about incomplete observations. In our empirical study, we identify key components when training early action prediction models. Our key contribution is a randomized training strategy that samples a time step separating observed and unobserved video frames, enabling a single model to generalize seamlessly across all test-time observation ratios. We further show that joint learning on both observed and future (oracle) representations significantly boosts performance, even allowing an encoder-only model to excel. To improve scalability, we propose a token masking procedure that cuts memory usage in half and accelerates training by 2× with no accuracy loss. Combined with a forecasting decoder, EAST sets a new state of the art on NTU60, SSv2, and UCF101, surpassing previous best work by 10.1, 7.7, and 3.9 percentage points, respectively. We support future research by releasing efficient training implementations and pre-trained models.

Poster
DVD-Quant: Data-free Video Diffusion Transformers Quantization

Zhiteng Li, Hanxuan Li, Junyi Wu, Kai Liu, Haotong Qin, Linghe Kong, Guihai Chen, Yulun Zhang, Xiaokang Yang

展开摘要

Diffusion Transformers (DiTs) have emerged as the state-of-the-art architecture for video generation, yet their computational and memory demands hinder practical deployment. While post-training quantization (PTQ) presents a promising approach to accelerate Video DiT models, existing methods suffer from two critical limitations: (1) dependence on computation-heavy and inflexible calibration procedures, and (2) considerable performance deterioration after quantization. To address these challenges, we propose DVD-Quant, a novel Data-free quantization framework for Video DiTs. Our approach integrates three key innovations: (1) Bounded-init Grid Refinement (BGR) and (2) Auto-scaling Rotated Quantization (ARQ) for calibration data-free quantization error reduction, as well as (3) $\delta$-Guided Bit Switching ($\delta$-GBS) for adaptive bit-width allocation. Extensive experiments across multiple video generation benchmarks demonstrate that DVD-Quant achieves an approximately 2$\times$ speedup over full-precision baselines on advanced DiT models while maintaining visual fidelity. Notably, DVD-Quant is the first to enable W4A4 PTQ for Video DiTs without compromising video quality. Code and models will be released to facilitate future research.

Poster
DA$^{2}$: Depth Anything in Any Direction

Haodong LI, Wangguandong Zheng, Jing He, Yuhao Liu, Xin Lin, Xin Yang, Ying-Cong Chen, Chunchao Guo

展开摘要

Panorama has a full FoV (360$^\circ\times$180$^\circ$), offering a more complete visual description than perspective images. Thanks to this characteristic, panoramic depth estimation is gaining increasing traction in 3D vision. However, due to the scarcity of panoramic data, previous methods are often restricted to in-domain settings, leading to poor zero-shot generalization. Furthermore, due to the spherical distortions inherent in panoramas, many approaches rely on perspective splitting (\textit{e.g.}, cubemaps), which leads to suboptimal efficiency. To address these challenges, we propose $\textbf{DA}$$^{\textbf{2}}$: $\textbf{D}$epth $\textbf{A}$nything in $\textbf{A}$ny $\textbf{D}$irection, an accurate, zero-shot generalizable, and fully end-to-end panoramic depth estimator. Specifically, for scaling up panoramic data, we introduce a data curation engine for generating high-quality panoramic depth data from perspective, and create $\sim$543K panoramic RGB-depth pairs, bringing the total to $\sim$607K. To further mitigate the spherical distortions, we present SphereViT, which explicitly leverages spherical coordinates to enforce the spherical geometric consistency in panoramic image features, yielding improved performance. A comprehensive benchmark on multiple datasets clearly demonstrates DA$^{2}$'s SoTA performance, with an average 38\% improvement on AbsRel over the strongest zero-shot baseline. Surprisingly, DA$^{2}$ even outperforms prior in-domain methods, highlighting its superior zero-shot generalization. Moreover, as an end-to-end solution, DA$^{2}$ exhibits much higher efficiency over fusion-based approaches. Both the code and the curated panoramic data have be released. Project page: https://depth-any-in-any-dir.github.io/.

Poster
Your Models Have Thought Enough: Training Large Reasoning Models to Stop Overthinking

Jinyi Han, Ying Huang, Ying Liao, Haiquan Zhao, Zishang Jiang, Xinyi Wang, Xikun Lu, Guanghao Zhou, Sihang Jiang, Jiaqing Liang, Weikang Zhou, Zeye Sun, Fei Yu, Yanghua Xiao

展开摘要

Large Reasoning Models (LRMs) have achieved impressive performance on challenging tasks, yet their deep reasoning often incurs substantial computational costs. To achieve efficient reasoning, existing reinforcement learning methods still struggle to construct short reasoning path during the rollout stage, limiting effective learning. Inspired by Evidence Accumulation Models, we find that LRMs have accumulated sufficient information early in reasoning, making further reasoning steps redundant. Based on this insight, we propose Just-Enough Thinking (JET), which trains models to proactively terminate unnecessary reasoning. JET performs trajectory truncation during rollout to expose the model to short, distributionally consistent reasoning paths. Besides, it uses a quality-controlled length reward to better encourage concise reasoning while maintaining correctness. Extensive experiments demonstrate that JET significantly improves reasoning efficiency without sacrificing accuracy. In particular, JET delivers a 4.6% accuracy improvement while reducing the output length by 46.3% on the Olympiad benchmark using DeepSeek-R1-Distill-Qwen-1.5B. Our code is available in the GitHub.

Poster
Hyden: A Hybrid Dual-Path Encoder for Monocular Geometry of High-resolution Images

Zaiwei Zhang, Marc Mapeke, Wei Ye, Rakesh Ranjan, JQ Huang

展开摘要

We present a hybrid dual-path vision encoder (Hyden) for high-resolution monocular depth, point map and surface normal estimation, surpassing state-of-the-art accuracy with a fraction of the inference cost. The architecture pairs a low-resolution Vision Transformer branch for global context with a full-resolution CNN branch for fine details, fusing features via a lightweight MLP before decoding. By exploiting the linear scaling of CNNs and constraining transformer computation to a fixed resolution, the model delivers fast inference even on multi-megapixel inputs. To overcome the scarcity of high-quality high-resolution supervision, we introduce a self-distillation framework that generates pseudo-labels from existing models at both lower resolution full images and high-resolution crops—global labels preserve geometric accuracy, while local labels capture sharper details. To demonstrate the flexibility of our approach, we integrate Hyden and our self-distillation method into DepthAnything-v2 for depth estimation and MoGe2 for surface normal and metric point map prediction, achieving state-of-the-art results on high-resolution benchmarks with the lowest inference latency among competing methods.

Poster
Loc$^{2}$: Interpretable Cross-View Localization via Depth-Lifted Local Feature Matching

Zimin Xia, Chenghao Xu, Alexandre Alahi

展开摘要

We propose an accurate and interpretable fine-grained cross-view localization method that estimates the 3 Degrees of Freedom (DoF) pose of a ground-level image by matching its local features with a reference aerial image. Unlike prior approaches that rely on global descriptors or bird’s-eye-view (BEV) transformations, our method directly learns ground–aerial image-plane correspondences using weak supervision from camera poses. The matched ground points are lifted into BEV space with monocular depth predictions, and scale-aware Procrustes alignment is then applied to estimate camera rotation, translation, and optionally the scale between relative depth and the aerial metric space. This formulation is lightweight, end-to-end trainable, and requires no pixel-level annotations. Experiments show state-of-the-art accuracy in challenging scenarios such as cross-area testing and unknown orientation. Furthermore, our method offers strong interpretability: correspondence quality directly reflects localization accuracy and enables outlier rejection via RANSAC, while overlaying the re-scaled ground layout on the aerial image provides an intuitive visual cue of localization accuracy.

Poster
Diverse Text Decoding via Iterative Reweighting

Ruiqi Shi, Sinno Jialin Pan

展开摘要

Recent advances in large language models (LLMs) have led to impressive results in text generation. However, current decoding methods still lack diversity when combined with popular sampling techniques. We propose a Reweighting-based Iterative DEcoding (OverRIDE) approach that dynamically adjusts the decoding process with history responses. Our method fine-tunes auxiliary output heads iteratively on previously generated sequences to capture and suppress semantic patterns that appear in the history responses. This inference-time training process only incurs minimal loss of efficiency. We conduct extensive experiments on various tasks, including code generation, mathematical reasoning and story generation, demonstrating that OverRIDE increases output diversity while maintaining quality. We implement OverRIDE on LLM serving systems like vLLM, achieving a 6.4\% throughput loss for 72B models under parallel decoding.

Poster
When would Vision-Proprioception Policies Fail in Robotic Manipulation?

Jingxian Lu, Wenke Xia, Yuxuan Wu, Zhiwu Lu, Di Hu

展开摘要

Proprioceptive information is critical for precise servo control by providing real-time robotic states. Its collaboration with vision is highly expected to enhance performances of the manipulation policy in complex tasks. However, recent studies have reported inconsistent observations on the generalization of vision-proprioception policies. In this work, we investigate this by conducting temporally controlled experiments. We found that during task sub-phases that robot's motion transitions, which require target localization, the vision modality of the vision-proprioception policy plays a limited role. Further analysis reveals that the policy naturally gravitates toward concise proprioceptive signals that offer faster loss reduction when training, thereby dominating the optimization and suppressing the learning of the visual modality during motion-transition phases. To alleviate this, we propose the Gradient Adjustment with Phase-guidance (GAP) algorithm that adaptively modulates the optimization of proprioception, enabling dynamic collaboration within the vision-proprioception policy. Specifically, we leverage proprioception to capture robotic states and estimate the probability of each timestep in the trajectory belonging to motion-transition phases. During policy learning, we apply fine-grained adjustment that reduces the magnitude of proprioception's gradient based on estimated probabilities, leading to robust and generalizable vision-proprioception policies. The comprehensive experiments demonstrate GAP is applicable in both simulated and real-world environments, across one-arm and dual-arm setups, and compatible with both conventional and Vision-Language-Action models. We believe this work can offer valuable insights into the development of vision-proprioception policies in robotic manipulation. Videos and code are available at https://gewu-lab.github.io/GAP/.

Poster
An Empirical Study of Attention and Diversity for Adaptive Visual Token Pruning in Large Vision-Language Models

Changwoo Baek, Jouwon Song, Sohyeon Kim, Kyeongbo Kong

展开摘要

Large Vision-Language Models (LVLMs) have adopted visual token pruning strategies to mitigate substantial computational overhead incurred by extensive visual token sequences. While prior works primarily focus on either attention-based or diversity-based pruning methods, in-depth analysis of these approaches' characteristics and limitations remains largely unexplored. In this work, we conduct thorough empirical analysis using effective rank (erank) as a measure of feature diversity and attention score entropy to investigate visual token processing mechanisms and analyze the strengths and weaknesses of each approach. Our analysis reveals two insights: (1) Our erank-based quantitative analysis shows that many diversity-oriented pruning methods preserve substantially less feature diversity than intended; moreover, analysis using the CHAIR dataset reveals that the diversity they do retain is closely tied to increased hallucination frequency compared to attention-based pruning. (2) We further observe that attention-based approaches are more effective on simple images where visual evidence is concentrated, while diversity-based methods better handle complex images with distributed features. Building on these empirical insights, we show that incorporating image-aware adjustments into existing hybrid pruning strategies consistently improves their performance. We also provide a minimal instantiation of our empirical findings through a simple adaptive pruning mechanism, which achieves strong and reliable performance across standard benchmarks as well as hallucination-specific evaluations. Our project page available at https://anonymous.4open.science/w/AdaVTP-186A/

Poster
ViTSP: A Vision Language Models Guided Framework for Large-Scale Traveling Salesman Problems

Zhuoli Yin, Yi Ding, Reem Khir, Hua Cai

展开摘要

Solving Traveling Salesman Problem (TSP) is NP-hard yet fundamental for wide real-world applications. Classical exact methods face challenges in scaling, and heuristic methods often require domain-specific parameter calibration. While learning-based approaches have shown promise, they suffer from poor generalization and limited scalability due to fixed training data. This work proposes ViTSP, a novel framework that leverages pre-trained vision language models (VLMs) to visually guide the solution process for large-scale TSPs. The VLMs function to identify promising small-scale subproblems from a visualized TSP instance, which are then efficiently optimized using an off-the-shelf solver to improve the global solution. ViTSP bypasses the dedicated model training at the user end while maintaining effectiveness across diverse instances. Experiments on real-world TSP instances ranging from 1k to 88k nodes demonstrate that ViTSP consistently achieves solutions with average optimality gaps below 0.2\%, outperforming existing learning-based methods. Under the same runtime budget, it surpasses the best-performing heuristic solver, LKH-3, by reducing its gaps by 12\% to 100\%, particularly on very-large-scale instances with more than 10k nodes. Our framework offers a new perspective in hybridizing pre-trained generative models and operations research solvers in solving combinatorial optimization problems, with practical implications for integration into more complex logistics systems. The code is available at https://anonymous.4open.science/r/ViTSP_codes-6683.

Poster
DETR-ViP: Detection Transformer with Robust Discriminative Visual Prompts

Bo Qian, Dahu Shi, Xing Wei

展开摘要

Visual prompted object detection enables interactive and flexible definition of target categories, thereby facilitating open-vocabulary detection. Since visual prompts are derived directly from image features, they often outperform text prompts in recognizing rare categories. Nevertheless, research on visual prompted detection has been largely overlooked, and it is typically treated as a byproduct of training text prompted detectors, which hinders its development. To fully unlock the potential of visual-prompted detection, we investigate the reasons why its performance is suboptimal and reveal that the underlying issue lies in the absence of global discriminability in visual prompts. Motivated by these observations, we propose DETR-ViP, a robust object detection framework that yields class-distinguishable visual prompts. On top of basic image-text contrastive learning, DETR-ViP incorporates global prompt integration and visual-textual prompt relation distillation to learn more discriminative prompt representations. In addition, DETR-ViP employs a selective fusion strategy that ensures stable and robust detection. Extensive experiments on COCO, LVIS, ODinW, and Roboflow100 demonstrate that DETR-ViP achieves substantially higher performance in visual prompt detection compared to other state-of-the-art counterparts. A series of ablation studies and analyses further validate the effectiveness of the proposed improvements and shed light on the underlying reasons for the enhanced detection capability of visual prompts.

Poster
Dynamic Texture Modeling of 3D Clothed Gaussian Avatars from a Single Video

Seungeun Lee, SeungJun Moon, Hah Min Lew, Ji-Su Kang, Gyeong-Moon Park

展开摘要

Recent advances in neural rendering, particularly 3D Gaussian Splatting (3DGS), have enabled animatable 3D human avatars from single videos with efficient rendering and high fidelity. However, current methods struggle with dynamic appearances, especially in loose garments (e.g., skirts), causing unrealistic cloth motion and needle artifacts. This paper introduces a novel approach to dynamic appearance modeling for 3DGS-based avatars, focusing on loose clothing. We identify two key challenges: (1) limited Gaussian deformation under pre-defined template articulation, and (2) a mismatch between body-template assumptions and the geometry of loose apparel. To address these issues, we propose a motion-aware autoregressive structural deformation framework for Gaussians. We structure Gaussians into an approximate graph and recursively predict structure-preserving updates, yielding realistic, template-free cloth dynamics. Our framework enables view-consistent and robust appearance modeling under the single-view constraint, producing accurate foreground silhouettes and precise alignment of Gaussian points with clothed shapes. To demonstrate the effectiveness of our method, we introduce an in-the-wild dataset featuring subjects performing dynamic movements in loose clothing, and extensive experiments validate that our approach significantly outperforms existing 3DGS-based methods in modeling dynamic appearances from single videos.

Poster
Histopathology-Genomics Multi-modal Structural Representation Learning for Data-Efficient Precision Oncology

Kun Wu, Zhiguo Jiang, Xinyu Zhu, Jun Shi, Yushan Zheng

展开摘要

Fusing histopathology images and genomics data with deep learning has significantly advanced precision oncology. However, genomics data is often missing due to its high acquisition cost and complexity in real-world clinical scenarios. Existing solutions aim to reconstruct genomics data from histopathology images. Nevertheless, these methods typically relied only on individual cases and overlooked the potential relationships among cases. Additionally, they failed to take advantage of the authentic genomics data of diagnostically related cases that are accessible from training for inference. In this work, we propose a novel Multi-modal Structural Representation Learning (MSRL) framework for data-efficient precision oncology. We pre-train a histopathology-genomics multi-modal representation graph adopting Graph Structure Learning (GSL) to construct inter-case relevance based on the data inherently. During the fine-tuning stage, we dynamically capture structural relevance between the training cases and the acquired authentic cases for precise prediction. MSRL leverages prior inter-case associations and authentic genomics data from diagnosed cases based on the graph, which contributes to effective inference based on the single histopathology image modality. We evaluated MSRL on public TCGA datasets with 7,263 cases across various tasks, including survival prediction, cancer grading, and gene mutation prediction. The results demonstrate that MSRL significantly outperforms existing missing-genomics generation approaches with improvements of 1.44% to 3.12% in C-Index on survival prediction tasks and achieves comparable performance to multi-modal fusion methods.

Poster
Cyber-Zero: Training Cybersecurity Agents without Runtime

Terry Yue Zhuo, Dingmin Wang, Hantian Ding, Varun Kumar, Zijian Wang

展开摘要

Large Language Models (LLMs) have achieved remarkable success in software engineering tasks when trained with executable runtime environments, particularly in resolving GitHub issues. However, such runtime environments are often unavailable in other domains, especially cybersecurity, where challenge configurations and execution contexts are ephemeral or restricted. We present Cyber-Zero, the first runtime-free framework for synthesizing high-quality agent trajectories to train cybersecurity LLMs. Cyber-Zero leverages publicly available CTF writeups and employs persona-driven LLM simulation to reverse-engineer runtime behaviors and generate realistic, long-horizon interaction sequences without actual environments. Using trajectories synthesized by Cyber-Zero, we train LLM-based agents that achieve up to 13.1% absolute performance gains over baseline models on three prominent CTF benchmarks: InterCode-CTF, NYU CTF Bench, and Cybench. Our best model, Cyber-Zero-32B, establishes new state-of-the-art performance among open-weight models, matching the capabilities of proprietary systems like DeepSeek-V3-0324 and Claude-3.5-Sonnet while offering superior cost-effectiveness, and demonstrating that runtime-free trajectory synthesis can effectively democratize the development of state-of-the-art cybersecurity agents.

Poster