ICML 2026 Papers

International Conference on Machine Learning

Decision breakdown

6,341papers

Counted from the official paper list; may differ slightly from the number the conference announced.

  • Spotlight
    5368.5%
  • Poster
    5,80591.5%

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Disentangling Latent Risk Pathways via Bayesian Hypergraph Inference

Shengxian Ding, Haonan Gao, Pangpang Liu, Xinyuan Tian, Yize Zhao

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Electronic health records (EHR) pose large-scale multi-disease modeling problems in which many outcomes are rare and strongly influenced by shared risk factors. While modern approaches achieve strong predictive performance, they often treat diseases independently or rely on black-box architectures, offering limited insight into how risk factors organize disease risk and little principled uncertainty quantification. We introduce a Bayesian hypergraph inference framework that reframes multi-disease modeling around **latent, risk-factor-modulated disease pathways**. Risk factors act on hyperedges, latent disease subsets with shared risk patterns, allowing diseases to participate in multiple distinct pathways and enabling interpretable, higher-order structure beyond pairwise associations. A repulsion prior encourages parsimonious and identifiable structure, while posterior inference provides calibrated uncertainty over both disease groupings and risk-factor influence. To enable scalable inference on large EHR datasets, we develop a structured variational inference algorithm that preserves logical dependencies among hyperedge existence, disease membership, and pathway-level effects. Experiments on simulated data and UK Biobank demonstrate stable and interpretable disease pathway structure, well-calibrated uncertainty, improved estimation for rare diseases, and competitive predictive performance.

Spotlight
Learning Anisotropic Value Geometry with Finsler Reinforcement Learning

Jumman Hossain, Nirmalya Roy

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We introduce **Finslerian Reinforcement Learning (FiRL)**, an RL framework that makes directional costs explicit and improves robustness to tail risk. FiRL incorporates a *Finsler metric* into the locomotion cost, expressing effort as $F(x,v)$ that depends on the state $x$ and motion $v$, so it can capture uphill versus downhill asymmetry, lateral slip, and other direction-dependent effects. To handle rare but catastrophic outcomes, FiRL optimizes a Conditional Value-at-Risk ($CVaR_\alpha$) objective. We derive the corresponding risk-sensitive Bellman equation and show that the resulting CVaR--Finsler Bellman operator is a $\gamma$-contraction. This guarantees a unique fixed-point value function, while the underlying Finsler cost induces an asymmetric path cost $d_F$ that satisfies a triangle inequality despite directional asymmetry. We then develop a FiRL actor--critic algorithm to learn policies under this anisotropic, risk-averse objective. Across simulation benchmarks and real-world robot trials, FiRL demonstrates safer and more energy-efficient locomotion behavior than strong baselines such as risk-neutral PPO. For instance, on a $12^\circ$ sloped Hopper task, FiRL reduces worst-case ($CVaR_{0.1}$) impact forces by over 35% and total energy cost by 15%, while also improving success rate.

Poster
PathwayLLM: Explainable Clinical Trajectory Modeling with Structured Pathways for Sepsis Prediction

Zhengqiu Yu, Yueping Ding, Xiangrong Liu

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Patient-level sepsis prediction requires models that track clinical deterioration over time and integrate heterogeneous structured evidence from electronic health records. We present PathwayLLM, a trajectory-based framework that grounds prediction on temporal signals, graph-structured evidence, and pathway-level clinical information derived from statistical dependency discovery. PathwayLLM follows a three-stage design. First, each observation window is encoded from multiple structured views, including physiological measurements, temporal dynamics, a heterogeneous patient-diagnosis-medication graph, and dependency-derived pathway signals. Second, these representations are injected into a pretrained language model as auxiliary contextual embeddings so that risk prediction and evidence-conditioned explanations can be learned jointly. Third, a Clinical Trajectory LSTM with Deterioration Attention aggregates window-level representations to highlight critical deterioration points and produce patient-level risk scores. On MIMIC-IV (15,410 ICU patients; 8.45% sepsis prevalence), PathwayLLM achieves AUROC 0.891 and AUPRC 0.724, outperforming strong time-series and pretrained baselines. External validation on eICU achieves AUROC 0.842 zero-shot and 0.867 after light fine-tuning. Ablation studies indicate that trajectory aggregation and structured clinical signals are key contributors, and clinician review suggests coherent, interpretable, and clinically relevant explanations.

Poster
Why ReLU? A Bit-Model Dichotomy for Deep Network Training

Ilan Doron-Arad, Elchanan Mossel

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Theoretical analyses of Empirical Risk Minimization (ERM) are standardly framed within the Real-RAM model of computation. In this setting, training even simple neural networks is known to be $\exists \mathbb{R}$-complete - a complexity class believed to be harder than NP, characterizing the difficulty of solving systems of polynomial inequalities over the real numbers. However, this algebraic framework diverges from the reality of digital computation with finite-precision hardware. In this work, we analyze the theoretical complexity of ERM under a realistic bit-level model (ERM-bit), where network parameters and inputs are constrained to be rational numbers with polynomially bounded bit-lengths. Under this model, we reveal a sharp dichotomy in tractability governed by the activation function: for deep networks with any polynomial activation with rational coefficients and degree at least $2$, deciding ERM-bit is #P-hard, determining the sign of a single partial derivative is unlikely to be in BPP, and deciding a specific bit in the gradient is #P-hard. In contrast, for piecewise-linear activations such as ReLU, precision requirements remain manageable: ERM-bit is in NP, indeed NP-complete, and standard backpropagation runs in polynomial time, showing that finite-precision constraints are not merely implementation details but fundamental determinants of learnability.

Poster
Decomposition-Based Modular Conformal Prediction for Two-Stage Modeling

William Zhang, Saurabh Amin, Georgia Perakis

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Conformal prediction offers finite-sample coverage guarantees under minimal assumptions. However, existing methods treat the entire modeling process as a black box, overlooking opportunities to exploit and understand modular structure. We introduce a conformal prediction framework for two-stage sequential models, where an upstream predictor generates intermediate representations for a downstream model. By decomposing the overall prediction residual into stage-specific components, our method enables practitioners to attribute uncertainty to specific pipeline stages. We develop a risk-controlled parameter selection procedure using family-wise error rate (FWER) control to calibrate stage-wise scaling parameters, and introduce an adaptive extension for non-stationary settings. Experiments on synthetic distribution shifts, as well as real-world supply chain and stock market data, demonstrate that our approach improves coverage under structural, stage-wise shifts compared to standard conformal methods, while identifying stage-wise error contribution. This framework offers diagnostic advantages and robust coverage that standard conformal methods lack.

Poster
Non-Parametric Probabilistic Robustness: A Conservative Risk Estimator under Unknown Perturbation Distributions

Zheng Wang, Yi Zhang, Siddartha Khastgir, carsten maple, Xingyu Zhao

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Deep learning (DL) models, despite their remarkable success, remain vulnerable to small input perturbations that can cause erroneous outputs, motivating the recent proposal of probabilistic robustness (PR) as a complementary alternative to adversarial robustness (AR). However, existing PR formulations assume a fixed and known perturbation distribution, an unrealistic expectation in practice. To address this limitation, we propose non-parametric probabilistic robustness (NPPR), a more practical PR metric that does not rely on any predefined perturbation distribution. Following the non-parametric paradigm in statistical modeling, NPPR learns an optimized perturbation distribution directly from data, enabling conservative PR evaluation under distributional uncertainty. We further develop an NPPR estimator based on a Gaussian Mixture Model (GMM), covering various input-dependent and input-independent perturbation scenarios. Theoretical analyses establish the relationships among AR, PR, and NPPR. Extensive experiments on CIFAR-10, CIFAR-100, and Tiny ImageNet across ResNet18/50, WideResNet50 and VGG16 validate NPPR as a more practical robustness metric, showing conservative (lower) PR estimates compared to assuming those common perturbation distributions used in state-of-the-arts.

Poster
New Wide-Net-Casting Jailbreak Attacks Risk Large Models

Qiuchi Xiang, Haoxuan Qu, Hossein Rahmani, Jun Liu

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Jailbreak attacks on large models have drawn growing attention due to their close ties to societal safety. This work identifies a practical yet unexplored jailbreak scenario, the wide-net-casting scenario, where an adversary can query a group of large models instead of a single one to elicit harmful outputs. Our analysis reveals substantial yet previously overlooked safety risks under this scenario. As a key part of our analysis, we further develop a novel jailbreak method tailored to the wide-net-casting scenario. With this tailored method, the jailbreak success rate can even reach 100% in some experiments when targeting the large models without additional safeguards, exposing wide-net-casting as a distinct, high-risk scenario that warrants attention in future evaluation and defense research.

Poster
Adversarially Robust Control of Conditional Value-at-Risk via Rockafellar-Uryasev Conformal Inference

Catherine Chen, Jingyan Shen, Zhun Deng, Lihua Lei

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We present an online, distribution-free framework for controlling the Conditional Value-at-Risk ($\operatorname{CVaR}$), extending conformal tail risk control to non-stationary and adversarial environments. Unlike classical risk control methods, which rely on stationarity or linearity of expectation, our approach provides provable safety guarantees for a nonlinear tail risk functional under arbitrary data-generating processes that may drift or shift strategically over time. By leveraging deep connections between conformal tail risk control, online learning, and the variational representation of $\operatorname{CVaR}$ introduced by Rockafellar and Uryasev, we develop a novel procedure for online $\operatorname{CVaR}$ control with adversarial regret guarantees. The proposed method operates without assumptions on the underlying data-generating process, making it broadly applicable in modern high-stakes deployment settings. We prove that the realized empirical $\operatorname{CVaR}$ is asymptotically controlled at the target level, and that the resulting control is asymptotically tight up to a finite-sample ${O}(1/\sqrt{T})$ conservatism gap. We demonstrate the effectiveness of our approach on portfolio risk management and toxicity mitigation for Large Language Models (LLMs), where rare but catastrophic failures dominate system risk.

Poster
Estimating Tail Risks in Language Model Output Distributions

Rico Angell, Raghav Singhal, Zachary Horvitz, Zhou Yu, Rajesh Ranganath, Kathleen McKeown, He He

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Language models are increasingly capable and are being rapidly deployed on a population-level scale. As a result, the safety of these models is increasingly high-stakes. Fortunately, advances in alignment have significantly reduced the likelihood of harmful model outputs. However, when models are queried billions of times in a day, even rare worst-case behaviors will occur. Current safety evaluations focus on capturing the distribution of inputs that yield harmful outputs. These evaluations disregard the probabilistic nature of models and their tail output behavior. To measure this tail risk, we propose a method to efficiently estimate the probability of harmful outputs for any input query. Instead of naive brute-force sampling from the target model, where harmful outputs could be rare, we operationalize importance sampling by creating unsafe versions of the target model. These unsafe versions enable sample-efficient estimation by making harmful outputs more probable. On benchmarks measuring misuse and misalignment, these estimates match brute-force Monte Carlo estimates using 10–20× fewer samples. For example, we can estimate probability of harmful outputs on the order of $10^{−4}$ with just 500 samples. Additionally, we find that these harmfulness estimates can reveal the sensitivity of models to perturbations in model input and predict deployment risks. Our work demonstrates that rare-event estimation is both critical and feasible for safety evaluations.

Spotlight
Optimal Transport for LLM Reward Modeling from Noisy Feedback

Licheng Pan, Haocheng Yang, Haoxuan Li, Yunsheng Lu, Yongqi Tong, Yinuo Wang, Shijian Wang, Zhixuan Chu, Lei Shen, Yuan Lu, Hao Wang

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Reward models are fundamental to Reinforcement Learning from Human Feedback (RLHF), yet real-world datasets are inevitably corrupted by noisy preference. Conventional training objectives tend to overfit these errors, while existing denoising approaches often rely on homogeneous noise assumptions that fail to capture the complexity of linguistic preferences. To handle these challenges, we propose SelectiveRM, a framework grounded in optimal transport. We first devise a Joint Consistency Discrepancy to align the distribution of model predictions with preference data. Furthermore, to address the limitation of strict mass conservation which compels the model to fit outliers, we incorporate a Mass Relaxation mechanism via partial transport. This enables the autonomous exclusion of samples with noisy preference that contradict semantic consistency. Theoretically, we demonstrate that SelectiveRM optimizes a tighter upper bound on the unobserved clean risk. Extensive experiments validate that our approach significantly outperforms state-of-the-art baselines across diverse benchmarks.

Poster
Correcting Overparameterization Effects in Fair Empirical Risk Minimization

Xiaoyi MAI, Jean-Michel Loubes

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Bias mitigation is particularly challenging for overparameterized machine learning (ML) models. Overfitting of training points not only amplifies data bias induced by spurious correlations, but also causes the failure of usual bias mitigation methods. To provide actionable insights to address this challenge, we propose a precise analysis of fair empirical risk minimization (ERM) in the overparameterized regime. Importantly, we show that even though conventional fair ERM fails on overparameterized models, this approach can be corrected by modifying the equality fairness constraint to allow for bias overcompensation. Moreover, our analysis presents an empirical criterion for strong equalized odds: balanced group-conditional means of representer coefficients, indicating equal average contribution from each sensitive group. Motivated by this result, we provide an estimable search interval that localizes the required overcompensation level for balanced coefficients. Despite the asymptotic nature of our findings, they closely capture the statistical behavior of moderately large ML models.

Poster
A Machine-Learned Comorbidity Index

Suleman Baloch, Kishlay Jha, Alberto Maria Segre, Philip M. Polgreen, Bijaya Adhikari

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Traditional comorbidity scores (e.g., Charlson and Elixhauser) are widely used for risk adjustment and patient stratification, but they have two key limitations: (i) they are largely mortality-centric and do not align well with other clinical outcomes, and (ii) their linear, rule-based structure cannot capture nonlinear, outcome-specific risk relationships. We propose a Machine-Learned Comorbidity Index (MLCI) that maps diagnosis codes to a single scalar by maximizing the normalized Hilbert–Schmidt Independence Criterion (nHSIC) between the learned score and multiple clinical outcomes. MLCI captures nonlinear risk–outcome dependence and is supported by a theory that characterizes when a unified, informative admission-level ordering can be achieved across outcomes. Empirical results on multiple benchmark electronic health record (EHR) datasets show that MLCI outperforms strong baselines across multiple evaluation metrics.

Poster
Reward Redistribution for CVaR MDPs using a Bellman Operator on L-infinity

Aneri Muni, Vincent Taboga, Esther Derman, Pierre-Luc Bacon, Erick Delage

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Tail-end risk measures such as static conditional value-at-risk (CVaR) are used in safety-critical applications to prevent rare, yet catastrophic events. Unlike risk-neutral objectives, the static CVaR of the return depends on entire trajectories without admitting a recursive Bellman decomposition in the underlying Markov decision process. A classical resolution relies on state augmentation with a continuous variable. However, unless restricted to a specialized class of admissible value functions, this formulation induces sparse rewards and degenerate fixed points. In this work, we propose a novel formulation of the static CVaR objective based on augmentation. Our alternative approach leads to a Bellman operator with: (1) dense per-step rewards; (2) contracting properties on the full space of bounded value functions. Building on this theoretical foundation, we develop risk-averse value iteration and model-free Q-learning algorithms that rely on discretized augmented states. We further provide convergence guarantees and approximation error bounds due to discretization. Empirical results demonstrate that our algorithms successfully learn CVaR-sensitive policies and achieve effective performance-safety trade-offs.

Spotlight
RiskZero: Plan More to Risk Less with a Learned Model

Yousef Yassin, Junfeng Wen

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*AlphaZero* and *MuZero* have demonstrated superhuman performance across a range of strategic tasks. Yet their reliance on maximizing expected returns limits their use in real-world settings, where even high-return policies may incur rare but catastrophic failures. We introduce *RiskZero* to address this limitation; the first *MuZero*-family method for risk-sensitive decision-making, and planning with *zero* prior knowledge of environment dynamics. *RiskZero* learns distributional quantities to estimate trajectory-level risk, guiding search toward policies that explicitly avoid rare but severe outcomes. We establish theoretical convergence to optimal, stationary risk-sensitive policies and validate our approach on environments designed to test risk-sensitive learning from pixels, as well as on larger-scale combinatorial tasks. Across all settings, *RiskZero* consistently outperforms state-of-the-art risk-sensitive baselines, and improves sample efficiency, providing a general framework for safer and reliable model-based reinforcement learning under uncertainty.

Poster