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arXiv

Diverging Transformer Predictions for Human Sentence Processing: A Comprehensive Analysis of Agreement Attraction Effects

Titus von der Malsburg, Sebastian Padó

Transformers underlie almost all state-of-the-art language models in computational linguistics, yet their cognitive adequacy as models of human sentence processing remains disputed. In this work, we use a surprisal-based linking mechanism to systematically evaluate eleven autoregressive transformers of varying sizes and architectures on a more comprehensive set of English agreement attraction configurations than prior work. Our experiments yield mixed results: While transformer predictions generally align with human reading time data for prepositional phrase configurations, performance degrades significantly on object-extracted relative clause configurations. In the latter case, predictions also diverge markedly across models, and no model successfully replicates the asymmetric interference patterns observed in humans. We conclude that current transformer models do not explain human morphosyntactic processing, and that evaluations of transformers as cognitive models must adopt rigorous, comprehensive experimental designs to avoid spurious generalizations from isolated syntactic configurations or individual models.

arXiv

The Company You Keep: How LLMs Respond to Dark Triad Traits

Angelica Henestrosa, Zeyi Lu, Pavel Chizhov, Ivan P. Yamshchikov

LLMs often exhibit highly agreeable conversational styles, also known as AI sycophancy. This pattern may become problematic when interacting with user prompts that reflect negative social tendencies, risking the amplification of harmful behavior. We examine how LLMs respond to user prompts expressing varying degrees of Dark Triad traits (Machiavellianism, Narcissism, and Psychopathy) using a curated dataset. Our analysis reveals systematic differences across models: while all models predominantly exhibit corrective behavior, some generate reinforcing or ambivalent output. Model behavior further varies with severity level and response sentiment. These findings highlight the need for safer conversational systems that can reliably detect and respond to users escalating from benign to harmful requests.

arXiv

FENCE: A Financial and Multimodal Jailbreak Detection Dataset

Mirae Kim, Seonghun Jeong, Youngjun Kwak

Jailbreaking poses a significant risk to the deployment of Large Language Models (LLMs) and Vision Language Models (VLMs). VLMs are particularly vulnerable because they process both text and images, creating broader attack surfaces. However, available resources for jailbreak detection are scarce, particularly in finance. To address this gap, we present FENCE, a bilingual (Korean-English) multimodal dataset for training and evaluating jailbreak detectors in financial applications. FENCE emphasizes domain realism through finance-relevant queries paired with image-grounded threats. Experiments with commercial and open-source VLMs reveal consistent vulnerabilities, with GPT-4o showing measurable attack success rates and open-source models displaying greater exposure. A baseline detector trained on FENCE achieves 99 percent in-distribution accuracy and maintains strong performance on external benchmarks, underscoring the dataset's robustness for training reliable detection models. FENCE provides a focused resource for advancing multimodal jailbreak detection in finance and for supporting safer, more reliable AI systems in sensitive domains. Warning: This paper includes example data that may be offensive.

arXiv

Beyond the Rabbit Hole: Mapping the Relational Harms of QAnon Radicalization

Bich Ngoc Doan, Gianmarco De Francisci Morales, Giuseppe Russo

Large-scale computational research on conspiracy theories has focused exclusively on believers' online behavior, leaving the harm experienced by those closest to them under-examined. This paper bridges this gap by analyzing 12747 stories from r/QAnonCasualties, an online support group for people who have ``lost'' someone to conspiracy beliefs. We design a computational pipeline to extract fine-grained thematic traits from personal narratives and cluster them into six coherent radicalization personas, which we then link to the emotional toll reported by narrators via LLM-assisted emotion detection and regression modeling. We find that personas are meaningful predictors of specific emotional harms: radicalization perceived as a deliberate ideological choice is associated with anger and disgust, while personas marked by personal and cognitive collapse correspond to fear and sadness. This work provides an empirically grounded computational framework for understanding the relational harms of radicalization, opening new avenues for research into its wider social consequences.

arXiv

Aligning Agentic World Models via Knowledgeable Experience Learning

Baochang Ren, Yunzhi Yao, Rui Sun, Shuofei Qiao, Ningyu Zhang, Huajun Chen

Current Large Language Models (LLMs) exhibit a critical modal disconnect: they possess vast semantic knowledge but lack the procedural grounding to respect the immutable laws of the physical world. Consequently, while these agents implicitly function as world models, their simulations often suffer from physical hallucinations-generating plans that are logically sound but physically unexecutable. Existing alignment strategies predominantly rely on resource-intensive training or fine-tuning, which attempt to compress dynamic environmental rules into static model parameters. However, such parametric encapsulation is inherently rigid, struggling to adapt to the open-ended variability of physical dynamics without continuous, costly retraining. To bridge this gap, we introduce WorldMind, a framework that autonomously constructs a symbolic World Knowledge Repository by synthesizing environmental feedback. Specifically, it unifies Process Experience to enforce physical feasibility via prediction errors and Goal Experience to guide task optimality through successful trajectories. Experiments on EB-ALFRED and EB-Habitat demonstrate that WorldMind achieves superior performance compared to baselines with remarkable cross-model and cross-environment transferability.

arXiv

Tracing the complexity profiles of different linguistic phenomena through the intrinsic dimension of LLM representations

Marco Baroni, Emily Cheng, Iria de-Dios-Flores, Francesca Franzon

We explore intrinsic dimension (ID) of LLM representations as a marker of linguistic complexity. Specifically, we test whether ID differences across model layers reflect well-known complexity contrasts established in (psycho)linguistics: coordination vs. subordination, right-branching vs. center-embedding, and unambiguous vs. ambiguous attachment. Our results on six different LLMs show that these contrasts are consistently reflected in ID differences, with more complex phenomena eliciting higher ID profiles. Notably, ID differences emerge at different points across layers for different contrasts, also reaching their peaks at different stages. Further experiments using representational similarity and layer pruning confirm the trends. We conclude that ID is a useful marker of linguistic complexity in LLMs, that it points to similar linguistic processing steps across disparate LLMs, and that it has the potential to differentiate between different types of complexity.

arXiv

OmniFusion: Simultaneous Multilingual Multimodal Translations via Modular Fusion

Sai Koneru, Matthias Huck, Jan Niehues

There has been significant progress in open-source text-only translation large language models (LLMs) with better language coverage and quality. However, these models can be only used in cascaded pipelines for speech translation (ST), performing automatic speech recognition first followed by translation. This introduces additional latency, which is particularly critical in simultaneous ST (SimulST), and prevents the model from exploiting multimodal context, such as images, which can aid disambiguation. Pretrained multimodal foundation models (MMFMs) already possess strong perception and reasoning capabilities across multiple modalities, but generally lack the multilingual coverage and specialized translation performance of dedicated translation LLMs. To build an effective multimodal translation system, we propose an end-to-end approach that fuses MMFMs with translation LLMs. We introduce a novel fusion strategy that connects hidden states from multiple layers of a pretrained MMFM to a translation LLM, enabling joint end-to-end training. The resulting model, OmniFusion, built on Omni 2.5-7B as the MMFM and SeedX PPO-7B as the translation LLM, can perform speech-to-text, speech-and-image-to-text, and text-and-image-to-text translation. Experiments demonstrate that OmniFusion effectively leverages both audio and visual inputs, achieves a 1-second latency reduction in SimulST compared to cascaded pipelines and also improves the overall translation quality\footnote{Code is available at https://github.com/saikoneru/OmniFusion}.

arXiv

Learning a Single Token to Replace Long System Prompts in LLMs

Jiancheng Dong, Pengyue Jia, Jingyu Peng, Maolin Wang, Yuhao Wang, Lixin Su, Xin Sun, Shuaiqiang Wang, Dawei Yin, Xiangyu Zhao

Long system prompts are widely used to steer Large Language Models (LLMs), but repeatedly processing them at inference time is inefficient and consumes valuable context budget. This motivates a central question: can the behavioral effect of a long system prompt be retained using only a minimal learned representation? To enable this, we propose a lightweight training framework that learns a single Behavior-Equivalent Token ([BE]). The framework first trains [BE] to encode the semantic content of the original system prompt via reconstruction, and then distills the prompt's downstream behavior into this single token. Importantly, our method requires no update to the pretrained LLM weights, no auxiliary compression models, and no labeled responses. Empirical evaluations on three datasets show that replacing long prompts with a single [BE] token yields up to a $3000\times$ prompt compression ratio, while retaining about 98% of the downstream performance of the original system prompts. This substantially reduces inference cost and frees nearly the entire context window for user inputs and model outputs.

arXiv

Think-at-Hard: Dynamic Looped Transformers for Improved Reasoning

Tianyu Fu, Yichen You, Zekai Chen, Guohao Dai, Huazhong Yang, Yu Wang

Improving the reasoning abilities of Large Language Models (LLMs), especially under parameter constraints, is crucial for real-world applications. Looped transformers address this by performing multiple latent iterations to refine each token beyond a single forward pass. However, we identify a latent overthinking phenomenon: most token predictions are already correct after the first pass, but are sometimes revised into errors in later iterations. We ask whether selectively skipping latent iterations can improve accuracy, and reveal significant potential with an oracle iteration policy that boosts performance by up to 7.3%. Motivated by this, we propose Think-at-Hard (TaH), a looped transformer optimized for selective iteration. TaH employs a lightweight neural decider to trigger latent iteration, only at tokens likely to be incorrect after the standard forward pass. During latent iterations, depth-aware Low-Rank Adaptation (LoRA) modules shift the objective from general next-token prediction to focused hard-token refinement. A duo-causal attention mechanism extends attention from the token sequence dimension to an additional iteration depth dimension, enabling cross-iteration information flow with full sequential parallelism. Experiments on nine benchmarks show consistent gains across math, QA, and coding tasks. With identical parameter counts, TaH outperforms always-iterate baselines by 3.8-4.4% while skipping iterations on 93% of tokens, and exceeds single-iteration Qwen3 baselines by 3.0-3.8%. When allowing <3% more parameters from LoRA and decider, the gains further increase to 5.3-6.2% and 6.1-6.8%, respectively. Our code is available at https://github.com/thu-nics/TaH.

arXiv

Multilingual Lexical Feature Analysis of Spoken Language for Predicting Major Depression Symptom Severity

Anastasiia Tokareva, Judith Dineley, Zoe Firth, Pauline Conde, Faith Matcham, Sara Siddi, Femke Lamers, Ewan Carr, Carolin Oetzmann, Daniel Leightley, Yuezhou Zhang, Amos A. Folarin, Josep Maria Haro, Brenda W. J. H. Penninx, Raquel Bailon, Srinivasan Vairavan, Til Wykes, Richard J. B. Dobson, Vaibhav A. Narayan, Matthew Hotopf, Nicholas Cummins, The RADAR-CNS Consortium

Background: Remotely captured spoken language could provide objective, regular indicators of depression symptom severity. However, research to date has largely used non-clinical, cross-sectional written language and complex machine learning (ML) approaches with limited interpretability. Methods: We used linear mixed-effect models to identify interpretable lexical features associated with symptom severity in data from the RADAR-MDD study that comprised 5,846 smartphone recordings and Patient Health Questionnaire (PHQ-8) scores from 467 participants in the UK, Netherlands and Spain. We then developed ML models and systematically assessed via nested cross-validation whether interpretable lexical features or high-dimensional vector embeddings improved the accuracy of PHQ-8 prediction over sociodemographic and confounding features. Results: Depression symptom severity was associated with five lexical features, including reductions in word count measures, use of first-person plural pronouns and positive word frequency. Associations were stable across countries, except for positive word frequency. Lexical features and vector embeddings did improve prediction accuracy beyond baseline models. Limitations: Our cohort was skewed in age (median = 53, IQR 35 to 62) and majority female (n=357), potentially affecting the generalizability of our results. A lack of natural language processing tools for non-English languages restricted our feature choices. Conclusion: Further research is required to realise the value of spoken lexical markers in clinical research and practice including larger and more diverse samples, elicitation protocol development and analytical methods that account for within- and between-individual variations.

arXiv

Roleplaying with Structure: Synthetic Therapist-Client Conversation Generation from Questionnaires

Doan Nam Long Vu, Rui Tan, Lena Moench, Svenja Jule Francke, Daniel Woiwod, Florian Thomas-Odenthal, Sanna Stroth, Tilo Kircher, Christiane Hermann, Udo Dannlowski, Hamidreza Jamalabadi, Simone Balloccu, Shaoxiong Ji

Large Language Models (LLMs) are promising tools for synthetic data generation in mental health. However, privacy policies and restrictions forced previous work to rely mainly on generic information. We present a comprehensive corpus of synthetic therapist-client conversations generated through LLMs. We construct our generation pipeline, SQPsych (Structured Questionnaire-based Psychotherapy), which uses real structured client profiles and psychological questionnaires without leaking any sensitive data. We fine-tune various open-weight LLMs on our generated corpus, SQPsychConv , and test them through both automatic benchmarks and human evaluation with trained psychotherapists. We find that standard benchmarks do not adequately capture the strengths of our dataset, but expert judgment shows that SQPsych makes LLMs significantly better at therapist roleplaying. Experts also consistently prefer therapy sessions generated by our models compared to other mental-health-oriented LLMs. We release our code, fine-tuned models SQPsychLLM, and corpora at https://ai-mh.github.io/SQPsych.html.

arXiv

Quantifying Affective Bias in Low-Resource Media: Large-Scale Emotion Profiling of Bengali Headlines

Mohd Ruhul Ameen, Akif Islam, Ayesha Siddiqua, Abu Saleh Musa Miah, Jungpil Shin

News media can influence readers not only through the events they report but also through the emotional tone used to present them. This issue is especially important in digital news environments, where headlines often shape first impressions before readers open the full article. This study examines affective framing in Bengali digital journalism through corpus level emotion analysis of news headlines. Using zero shot inference with Gemma 3 4B, we analyzed 300,000 Bengali news headlines to estimate the dominant emotion and overall affective tone of each headline. The results show that negative emotion labels, particularly anger, sadness, disappointment, and fear, appear frequently in the analyzed corpus. A small pilot validation on 200 manually reviewed headlines suggests that the model can provide useful emotion estimates, although the results should be interpreted as computational estimates rather than a complete benchmark. Based on these findings, we propose a conceptual bias sensitive news interface that visualizes emotional cues across news sources and helps readers notice affective framing patterns in daily news.

arXiv

OceanGym: A Benchmark Environment for Underwater Embodied Agents

Yida Xue, Mingjun Mao, Xiangyuan Ru, Yuqi Zhu, Baochang Ren, Shuofei Qiao, Mengru Wang, Shumin Deng, Xinyu An, Ningyu Zhang, Ying Chen, Huajun Chen

We introduce OceanGym, the first comprehensive benchmark for ocean underwater embodied agents, designed to advance AI in one of the most demanding real-world environments. Unlike terrestrial or aerial domains, underwater settings present extreme perceptual and decision-making challenges, including low visibility, dynamic ocean currents, making effective agent deployment exceptionally difficult. OceanGym encompasses eight realistic task domains and a unified agent framework driven by Multi-modal Large Language Models (MLLMs), which integrates perception, memory, and sequential decision-making. Agents are required to comprehend optical and sonar data, autonomously explore complex environments, and accomplish long-horizon objectives under these harsh conditions. Extensive experiments reveal substantial gaps between state-of-the-art MLLM-driven agents and human experts, highlighting the persistent difficulty of perception, planning, and adaptability in ocean underwater environments. By providing a high-fidelity, rigorously designed platform, OceanGym establishes a testbed for developing robust embodied AI and transferring these capabilities to real-world autonomous ocean underwater vehicles, marking a decisive step toward intelligent agents capable of operating in one of Earth's last unexplored frontiers. The code and data are available at https://github.com/OceanGPT/OceanGym.

arXiv

Steering Multimodal Large Language Models Decoding for Context-Aware Safety

Zheyuan Liu, Zhangchen Xu, Guangyao Dou, Xiangchi Yuan, Zhaoxuan Tan, Radha Poovendran, Meng Jiang

Multimodal Large Language Models (MLLMs) are increasingly deployed in real-world applications, yet their ability to make context-aware safety decisions remains limited. Existing methods often fail to balance oversensitivity (unjustified refusals of benign queries) and undersensitivity (missed detection of visually grounded risks), leaving a persistent gap in safety alignment. To address this issue, we introduce Safety-aware Contrastive Decoding (SafeCoDe), a lightweight and model-agnostic decoding framework that dynamically adjusts token generation based on multimodal context. SafeCoDe operates in two stages: (1) a contrastive decoding mechanism that highlights tokens sensitive to visual context by contrasting real and Gaussian-noised images, and (2) a global-aware token modulation strategy that integrates scene-level reasoning with token-level adjustment to adapt refusals according to the predicted safety verdict. Extensive experiments across diverse MLLM architectures and safety benchmarks, covering undersensitivity, oversensitivity, and general safety evaluations, show that SafeCoDe consistently improves context-sensitive refusal behaviors while preserving model helpfulness.

arXiv

Cognitive Chain-of-Thought (CoCoT): Structured Multimodal Reasoning about Social Situations

Eunkyu Park, Wesley Hanwen Deng, Gunhee Kim, Motahhare Eslami, Maarten Sap

Chain-of-Thought (CoT) prompting helps models think step by step. But naive CoT breaks down in visually grounded social tasks, where models must perceive, understand, and judge all at once; bridging perception with norm-grounded reasoning. Recent work has introduced structured reasoning for multi-turn agent planning and visual QA, decomposing tasks into sequential sub-goals. To extend this to single-shot multimodal social reasoning, we introduce Cognitive Chain-of-Thought (CoCoT), a reasoning framework that structures vision-language-model (VLM) reasoning through three cognitively inspired stages: Perception (extract grounded facts), Situation (infer situations), and Norm (applying social norms). Evaluation across multiple distinct tasks such as multimodal intent disambiguation, multimodal theory of mind, social commonsense reasoning, and safety instruction following, shows consistent improvements (5.9% to 4.6% on average). We further explore the utility of CoCoT for improving models' reasoning through training and show that supervised fine-tuning on CoCoT-structured traces yields 5-6% improvements without explicit CoCoT prompting at inference, demonstrating that models internalize the structured reasoning pattern rather than merely following instructions. We show that structuring model reasoning through cognitively grounded stages enhances interpretability and social alignment, laying the groundwork for more reliable multimodal systems.

arXiv

PRISM: Self-Pruning Intrinsic Selection Method for Training-Free Multimodal Data Selection

Jinhe Bi, Aniri, Zengjie Jin, Yifan Wang, Danqi Yan, Wenke Huang, Xiaowen Ma, Sikuan Yan, Artur Hecker, Mang Ye, Xun Xiao, Hinrich Schuetze, Volker Tresp, Yunpu Ma

Visual instruction tuning adapts pre-trained Multimodal Large Language Models (MLLMs) to follow human instructions for real-world applications. However, the rapid growth of these datasets introduces significant redundancy, leading to increased computational costs. Existing methods for selecting instruction data aim to prune this redundancy, but predominantly rely on computationally demanding techniques such as proxy-based inference or training-based metrics. Consequently, the substantial computational costs incurred by these selection processes often exacerbate the very efficiency bottlenecks they are intended to resolve, posing a significant challenge to the scalable and effective tuning of MLLMs. To address this challenge, we first identify a critical, yet previously overlooked, factor: the anisotropy inherent in visual feature distributions. We find that this anisotropy induces a \textit{Global Semantic Drift}, and overlooking this phenomenon is a key factor limiting the efficiency of current data selection methods. Motivated by this insight, we devise \textbf{PRISM}, the first training-free framework for efficient visual instruction selection. PRISM surgically removes the corrupting influence of global background features by modeling the intrinsic visual semantics via implicit re-centering. Empirically, PRISM reduces the end-to-end time for data selection and model tuning to just 30\% of conventional pipelines. More remarkably, it achieves this efficiency while simultaneously enhancing performance, surpassing models fine-tuned on the full dataset across eight multimodal and three language understanding benchmarks, culminating in a 101.7\% relative improvement over the baseline. The code is available for access via \href{https://github.com/bibisbar/PRISM}{this repository}.

arXiv

Long Story Short: Story-level Video Understanding from 20K Short Films

Ridouane Ghermi, Xi Wang, Vicky Kalogeiton, Ivan Laptev

Recent developments in vision-language models have significantly advanced video understanding. Existing datasets and tasks, however, have notable limitations. Most datasets are confined to short videos with limited events and narrow narratives. For example, datasets with instructional and egocentric videos often depict the activities of one person in a single scene. Although existing movie datasets offer richer content, they are often limited to short-term tasks, lack publicly available videos, and frequently encounter data leakage issues given the use of subtitles and other information about commercial movies during LLM pretraining. To address the above limitations, we propose Short-Films 20K (SF20K), the largest publicly available movie dataset. SF20K consists of 20,143 amateur films, amounting to 3,582 hours of video, with an average of 12 minutes per movie. We accompany this dataset with SF20K-Test, a manual, open-ended question answering benchmark. SF20K-Test consists of 95 movies and 979 question-answer pairs. Our extensive analysis of SF20K-Test reveals limited data leakage, emphasizes the need for long-term reasoning, and demonstrates the strong performance of recent VLMs. Finally, we show that instruction tuning on the large-scale dataset substantially improves model performance, paving the way for future progress in long-term video understanding.

arXiv

Evaluating the Performance of Large Language Models on GAOKAO Benchmark

Xiaotian Zhang, Chunyang Li, Yi Zong, Zhengyu Ying, Liang He, Xipeng Qiu, Tianxiang Sun, Peng Li, Shiqiao Meng, Yanjun Zheng, Jun Zhan, Zhangyue Yin, Xiannian Hu, Guofeng Quan, Qixiang Wang

Large Language Models(LLMs) have demonstrated remarkable performance across various natural language processing tasks; however, how to comprehensively and accurately assess their performance becomes an urgent issue to be addressed. This paper introduces GAOKAO-Bench, an intuitive benchmark that employs questions from the Chinese GAOKAO examination as test samples, including both subjective and objective questions. To align with human examination methods, we design a method based on zero-shot settings to evaluate the performance of LLMs. With human evaluation, we obtain the converted total score of LLMs, including GPT-4, ChatGPT and ERNIE-Bot.Our findings reveal that LLMs have achieved competitive scores in Chinese GAOKAO examination, while they exhibit significant performance disparities across various subjects. We also use LLMs to grade the subjective questions, and find that model scores achieve a moderate level of consistency with human scores. In conclusion, this research contributes a robust evaluation benchmark for future large language models and offers valuable insights into the advantages and limitations of such models.

arXiv

Enhancing MRI Brain Tumor Edge Detection: A Hybrid Preprocessing Approach Utilizing CLAHE

Shahid-E-Kaiser Md. Tashrif, Munshi Md Arafat Hussain, Sheikh Nahian, Sumaiya Islam

Accurate boundary delineation of brain tumors in Magnetic Resonance Imaging (MRI) is a critical yet formidable challenge in neuro-oncology due to inherent scanner noise, complex anatomical structures, and uneven illumination. Traditional edge detection algorithms, while computationally lightweight and mathematically interpretable, frequently fail to capture the diffuse, localized boundaries of edema when relying solely on global preprocessing and manual parameter tuning. To overcome these limitations, we propose a hybrid automated edge detection pipeline. Our approach integrates an optimally configured Contrast-Limited Adaptive Histogram Equalization (CLAHE) layer into a comprehensive morphological preprocessing framework, followed by a deterministic sequential parameter sweep to fully automate threshold selection. The proposed hybrid model demonstrated enhancement in detecting critical anatomical structures in a publicly available benchmark database from Kaggle. By intelligently amplifying localized gradients without overwhelming the image with background noise, our method achieved higher Recall (Sensitivity). Consequently, the overall F1-Score elevated, and the Structural Similarity Index (SSIM) improved, all while maintaining a highly efficient execution. This establishes our optimized pipeline as a highly practical and near real-time operational model for clinical diagnostics, offering a compelling alternative to computationally heavy deep learning approaches.

arXiv

STEP: A Modular Silent Trial Engine for Operational Evaluation of Digital Pathology AI in Routine Workflow

Gabriele Campanella, Matthew Croken, Olga Lukatskaya, Jane Houldsworth, Ricky Kwan, Peter Schüffler, Chad Vanderbilt

Prospective silent trials provide an important bridge between retrospective validation of artificial intelligence (AI) models and their use in clinical care by evaluating model performance and operational reliability on live clinical data without influencing patient management. In computational pathology, conducting silent trials requires integration across laboratory information systems, digital pathology infrastructure, computational resources, and model inference pipelines, and these workflows are often implemented using application-specific software. We developed the Silent Trial Engine for Pathology (STEP), a reusable software platform for orchestrating prospective silent trials of computational pathology AI models across heterogeneous clinical and computational environments. STEP separates common trial orchestration from institution-specific data access and compute infrastructure through modular adapter interfaces. The platform supports scheduled case discovery, per-slide inference submission, deterministic idempotency, failure recovery, result and ancillary-data ingestion, persistent trial and run state, and audit logging, with compute adapters supporting local execution and high-performance computing environments using LSF and Slurm. STEP was deployed at three institutions to support prospective silent evaluation of EAGLE, an AI model for predicting EGFR mutation status from hematoxylin and eosin-stained whole-slide images. By separating trial-level workflow logic from site-specific integrations, STEP enables a common execution framework to operate across heterogeneous pathology environments while maintaining durable and auditable trial state. This approach may reduce duplicated engineering effort and facilitate systematic real-world evaluation of computational pathology AI before interventional clinical deployment.

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