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Search papers from 30+ top conferences, including NeurIPS, ICLR, ICML, CVPR, ACL and AAAI. Filter by keyword, then open any paper for its abstract, authors and links.

arXiv

Interaction Creates Dynamical AI Behavior Absent in Isolation

Bella Xinrui Li, Frank Yingjie Huo, Neil F. Johnson

What will happen when AI agents interact in daily life, e.g. when one AI starts bossing another around? We find a counterintuitive answer that opens new avenues for out-of-equilibrium Physics. When a boss AI directs a stream of messages at the subordinate AI while ignoring its replies, it drives the subordinate into an alien behavioral state that it would never have exhibited alone. Although the two AIs share the same well-defined (decoding) temperature, the subordinate neither copies its boss nor returns to how it behaves on its own; instead, it adopts an entirely different behavior. The boss's added value is similar to a pre-recorded tape. When the boss listens, they both adopt a similar alien dynamical state. A simple kinetic theory captures the principal effects, such as why the way in which the same messages are delivered will matter in future AI-AI interactions.

arXiv

Strategy-first synthesis planning for complex natural products

Daniel Armstrong, Xuan-Vu Nguyen, Octavian Susanu, Gabriel Gibberd, Théo A. Neukomm, Taddäus Strunden, Dan Forster, Morgane Delattre, Shawn Teh, Clément Rols, John Federice, Hayden Leatherwood, M. Lavelle Barnes, Maarten R. Dobbelaere, Peter Wipf, Jon T. Njardarson, Jieping Zhu, Philippe Schwaller

The total synthesis of a complex molecule is among the most demanding intellectual and experimental feats in chemistry: a chemist must plan many steps ahead for how to assemble simple building blocks into an intricate target, devise backup strategies, and anticipate procedural challenges. It is also a profoundly creative activity. For half a century, efforts to automate the retrosynthetic design of natural products and other complex molecules have drawn on catalogued reactions, and the resulting tools now report near-complete success on benchmarks built from that same source. But these tools were shaped to fit benchmarked chemistry, and they falter on many natural products, the frontier of the field, whose densely functionalized, polycyclic architectures demand precisely the inventive chemistry the record contains least. Whether a machine could reasonably design such syntheses like an expert chemist does has remained unclear. Here, we show that SynthEx, an agentic framework built on large language models, plans routes to complex natural products that lie beyond the reach of conventional design algorithms. SynthEx proposes competing strategies, assembles a sequence of routine and key steps into a cohesive route, and critiques and improves its own design; the chemistry it favours is more convergent than existing tools produce, and spans a region of reaction space that catalogue-based tools cannot match. Most notably, in blinded assessments, expert chemists judged its key steps comparable to those of published human syntheses and engaged with them as genuine synthesis plans, a response algorithmic route prediction has not previously accomplished. We release routes to more than a thousand natural products as SynthAtlas, an open, interactive database, and anticipate it will become a shared resource for a collection of complex target molecules that lack existing literature routes.

arXiv

Taxonomy-Driven Analysis of Open-Source AI Risk Mitigation Tools

Afreen Alam, Evgenija Popchanovska, Ana Gjorgjevikj, Maryan Rizinski, Lubomir T. Chitkushev, Irena Vodenska, Dimitar Trajanov

Rapid adoption of large language models (LLMs) in enterprise settings has introduced operational, security, and governance risks. As generative AI applications move from pilot to production, manual harm identification and mitigation are becoming difficult to scale. Although many tools support model evaluation, adversarial testing, runtime guardrails, and observability, the tooling landscape remains fragmented. Tools are typically designed for specific engineering tasks and described in technical terms that do not align with governance frameworks or risk taxonomies, making it difficult to determine which tools address which risks and where critical gaps remain. This paper proposes a structured protocol to automate AI risk mitigation through a taxonomy-driven analysis of open-source LLM evaluation and security tools. We map the capabilities of 21 prominent open-source tools to the 32 subcategories of the extended MIT AI Risk Mitigation and Response Taxonomy. An LLM-assisted retrieval-augmented generation pipeline analyzes source code and documentation to extract capabilities for each taxonomy category. Reliability assessment yielded moderate agreement (Fleiss' Kappa = 0.509) among three independent reviewers. The analysis reveals a highly skewed landscape in which tools cluster around technical and operational controls, while governance, legal and regulatory, and financial and market controls remain largely unaddressed. This motivates a layered risk-mitigation architecture combining tool-based controls with organizational and regulatory processes. The mapping protocol achieved an F1 score of 75.5% after majority voting. Overall, the study provides a practical mapping between enterprise AI risk categories and open-source mitigation capabilities, identifies where human oversight remains necessary, and presents a taxonomy-driven framework applicable to open-source and proprietary solutions.

arXiv

Fisher-R1: Training LLM Agents for Reliable Hypothesis Testing

Jiacheng Miao, Jin Mu, Guanhua Chen, James Zou

Reliable hypothesis testing is the foundation of many empirical scientific claims. Large language model (LLM) agents are increasingly used to automate this process, as they can inspect datasets, generate code, and produce analyses end-to-end. However, we show that they frequently make subtle inferential errors that lead to incorrect conclusions despite correctly executed analyses. Existing benchmarks fail to capture this failure mode, as they rarely assess whether a reported p-value is statistically valid given the assumptions underlying the data. We address this gap by building P-Bench, a benchmark comprising 425 open-ended, realistic hypothesis-testing tasks spanning economics, biology, and medicine. Each task requires an agent to select a statistical method, compute a p-value, and draw a conclusion given only a scientific hypothesis and a dataset. We further introduce Fisher-R1, an open-weight LLM agent trained for rigorous hypothesis testing using synthetic tasks and reinforcement learning. On P-Bench, Fisher-R1-14B substantially improves over its backbone and outperforms strong proprietary and open-source baselines, including GPT-5.4 and DeepSeekV4-Pro, achieving a 21% average relative improvement in single-trial success over DeepSeek-V4-Pro, with gains up to 26% on the most challenging tasks. Our results demonstrate that current LLM agents lack reliable statistical reasoning for hypothesis testing and that reinforcement learning on tasks with verified statistical reward substantially improves reliability.

arXiv

A Picture is Worth a Thousand Tokens: How Vision Language Models Cut AI Energy Costs While Improving Accuracy

Bhavika Jalli, Nikhil Korati Prasanna, Jayanta Choudhury

LLM inference accounts for over 90% of AI operational energy, scaling directly with input token count---a critical inefficiency for telecom network analytics and numerical time-series data analysis (NTSDA), where raw multivariate KPI windows from 4G/5G cell sites expand into thousands of floating-point tokens. Vision-Language Models (VLMs) eliminate this mismatch by encoding time-series as 2D plots, achieving 3.6-10.4x input token reduction across Llama-3.2-90B, Qwen2.5-VL-72B, and Pixtral-12B architectures. This translates to 1.8-2.5x measured inference energy reduction, saving approximately 7.2 MJ/day at telecom edge deployments and CloudRAN that monitor 200 cells per 15-minute interval. Critically, efficiency gains do not sacrifice accuracy: a fine-tuned Llama-3.2-90B-Vision VLM achieves 220.7% higher precision than its text-only counterpart and outperforms LSTM and ARIMA baselines by over 144% on telecom anomaly detection. On public benchmarks, Pixtral-12B achieves a 20.6x improvement in J/F1 score at mean F1 = 0.82. At 24 KPIs, text representations exceed the 128K context window of most production LLMs, rendering text-only processing infeasible without truncation, while visual representations remain within standard limits. These results establish VLMs as an energy-efficient and accuracy-superior modality for numerical time-series workloads, providing empirical grounding for AI inference systems that treat energy consumption as a first-class engineering constraint.

arXiv

FinRank: An Evidence-Grounded Benchmark for Financial Question Answering and Retrieval over SEC Filings

Sasan Mansouri, Daniel Saad, Mark Wahrenburg, Manu Weissel, Fabian Woebbeking

Financial question answering is typically evaluated by answer correctness, yet in SEC filings a plausible and even numerically correct answer can be grounded in the wrong evidence. Similar facts and disclosures recur across sections of a filing, across reporting periods of the same firm, and across comparable firms. FinRank targets this provenance-sensitive retrieval problem by requiring systems to identify evidence for the intended entity, reporting period, and disclosure context. The benchmark contains 1185 manually authored question-answer records over the 10-K and 10-Q filings of 22 companies. Each record includes a reference answer, gold supporting passages, and hand-curated hard negatives drawn from confusable passages within filings, across reporting periods, and across comparable firms. FinRank evaluates passage retrieval, reranking, and hard-negative discrimination as separately measured tasks. Baseline results demonstrate the difficulty of this setting: among the evaluated systems, even a 7B instruction-tuned embedder reaches only 44.8% Recall@10 on the pooled evidence corpus; sub-billion-parameter encoders gain at most 3.5 points over BM25, a finance-adapted embedder trails BM25 by 9.7 points, and pairwise accuracy falls by 13.0-20.5 percentage points when random negatives are replaced with the curated hard negatives. FinRank provides an evidence-first benchmark for developing financial question answering systems that are not only accurate but also grounded in the correct disclosure.

arXiv

PACE: Primitive-Aware Code Evolution for Automated Algorithm Design

Zhuoliang Xie, Ruihao Zheng, Xiang Xu, Genghui Li, Zhengkun Wang

Large Language Model (LLM)-based automated algorithm design typically evolves algorithms as complete, indivisible programs. While this whole-program perspective simplifies the search space, it fundamentally couples the useful local logic to its host program. Consequently, valuable code snippets vanish when the overall program is discarded, making it highly difficult to assess the contribution of individual algorithmic components.To address this, we propose Primitive-Aware Code Evolution (PACE), which decouples local logic from complete programs by representing it as persistent units called Executable Algorithmic Primitives (EAPs). To enable code-level transfer, PACE maintains a dynamic set of EAPs. Algorithm evolution is driven by primitive-aware operators that structurally guarantee the retention and cross-program transfer of these components. To evaluate them effectively, PACE leverages Thompson sampling based on parent-relative performance improvements, guiding primitive selection from the set without requiring extra evaluation datasets. Experiments on four tasks demonstrate that PACE effectively discovers competitive algorithms while structurally preserving valuable algorithmic components.

arXiv

People Are Not Just Their Countries. Disentangling Social Determinants of LLM Value Alignment Across Europe

Maria-Louisa Wightman, Guillaume Bied, Tijl De Bie

As Large Language Models (LLMs) are increasingly used as a primary source of information and advice, understanding their alignment to humans in terms of values becomes a pressing concern. A growing literature has leveraged large scale surveys to investigate to what extent LLMs' and humans' stated values and opinions align. With limited exceptions, studied populations have been defined country borders or cultural bounds. Yet, this focus neglects the role that socio-demographic divides may play for value alignment disparities. Relying on the European Social Survey, we address this knowledge gap by considering value alignment displayed with respect to 10 prominent commercial LLMs in terms of 15 socio-demographic variables as well as country of residence. Our analyses reveal that LLMs are indeed unequally aligned to the values of different socio-demographic groups, notably those defined by education, income, occupation and religion. When examining alignment at the individual level, a respondent's country, taken as a stand-alone variable, explains a substantial amount of variation that is on par with the full set of considered socio-demographics. Further disentangling the respective role of country-level and socio-demographic factors, we find they are complementary in explaining value alignment patterns, with their relative weights varying across the subset of questions considered.

arXiv

Full-Stack FP4: Stable LLM Pretraining with Quantized Projections, Optimizers, and Attention

Siyu Ding, Mingchuan Ma, Jiabo Tong, Xingrun Xing, Ziming Wang, Guoqi Li

Recent NVFP4 pretraining work has primarily optimized Transformer linear projections, leaving persistent optimizer states, optimizer computation, and low-precision attention forward--backward paths less explored. We present \textbf{Full-Stack FP4}, a modular NVFP4 framework with separate recipes for projections, AdamW states, Root/Muon computation, and attention. \textbf{LoRA-SVD} protects a compact projection subspace in BF16 while retaining full-shape NVFP4 computation, reducing the linear-only loss gap from \textbf{1.40\%} to \textbf{0.61\%}. An ordered square-root, tile-mean, and Hadamard pipeline enables stable NVFP4 AdamW momentum storage; shape-dependent coefficients and clipping stabilize direct NVFP4 Root iterations; and mixed-precision attention retains softmax-sensitive operations in BF16. On 3B pretraining with 64B tokens, BF16 and Full-Stack FP4 reach losses of \textbf{2.267} and \textbf{2.286}, a \textbf{0.838\%} gap. Their average zero-shot perplexities are 26.675 and 26.665, respectively, with Full-Stack FP4 averaging 0.10 percentage points lower in accuracy. Native four-block measurements on one RTX 5090 show 2.50--2.83$\times$ Root speedups over optimized BF16 and 37.9--42.5\% lower AdamW peak memory.

arXiv

Curriculum as Code: An AI-Assisted Architecture for Instructional Design in STEM Education

Henrique Mohallem Paiva

Contribution: This paper presents a six-phase AI-assisted instructional design architecture based on the Curriculum as Code paradigm, integrating Generative AI with LaTeX and Python to automate the creation of reproducible, visually consistent, and technically precise materials for STEM education. Background: Creating customized instructional materials for active learning imposes a heavy workload on faculty. Standard presentation tools lack robust support for technical content, while current AI applications often hallucinate and fail to formalize the instructional authoring process, limiting their utility for rigorous academic design. Intended Outcomes: The framework aims to reduce preparation time while ensuring mathematical accuracy, adherence to institutional visual identity, and preservation of the instructor's tacit pedagogical knowledge through explicit rules. Application Design: The solution comprises a six-phase pipeline that replaces ad-hoc prompt engineering with a systematic workflow, utilizing text-based interfaces and code-driven generation (LaTeX/Beamer for slides, Python for figures), governed by pedagogical constraints, contextual calibrations, and automated review cycles. Findings: Validated over one year across 8 modules and 28 project contexts in a Project-Based Learning environment, the architecture significantly reduced instructor workload. Generated assets underwent independent peer review and were deployed by six different faculty members, confirming scalability beyond a single author. Based on over 600 voluntary student evaluations, materials achieved high quality ratings from 8.5 to 9.9/10. Results indicate high reproducibility, minimized hallucinations, and sustained pedagogical and visual fidelity, suggesting viability for broad STEM educational applications.

arXiv

QFCQT: A Chaotically Gated Quantformer Framework for Volatile Time-Series Forecasting

Junkai Lin, Siqi Hou, Raymond Lee

Forecasting non-stationary time series remains difficult due to long-range dependencies, local volatility bursts, structural shifts, and nonlinear oscillatory behaviors. Although Transformer-based forecasters are effective for modeling long-term temporal dependencies, their feed-forward blocks typically rely on smooth static activations that are insufficiently sensitive to abrupt regime changes. Motivated by quantitative Transformer designs and oscillator-based nonlinear activations, we propose QFCQT, short for Quantum-Fractal-inspired Chaotically Gated Quantformer, for robust forecasting under complex volatile dynamics. Here, "quantum-fractal-inspired" denotes a computational analogy based on soft oscillator superposition and multi-scale nonlinear responses, rather than a formal quantum-mechanical or fractal-theoretic derivation. QFCQT consists of three main components: (1) a Quantformer-style numerical encoder that directly processes multivariate inputs via linear embedding; (2) a learnable Lee-oscillator activation module that maps scalar pre-activations to dynamic oscillatory responses and summarizes them through Max-over-Time pooling; and (3) a smooth-chaotic gated fusion mechanism that adaptively balances conventional smooth activations and chaos-sensitive responses. Furthermore, instead of using a single fixed oscillator, QFCQT employs a soft superposition of eight parameterized Lee oscillator families to adaptively capture different nonlinear response patterns across regimes. Experiments on ETTh1, ETTh2, and A-share Stock Index benchmarks show that QFCQT consistently outperforms strong baselines, including Informer, LogTrans, LSTMa, HAT, and COTN.

arXiv

Assessing AI-generated music detection in real-world broadcast monitoring

David López-Ayala, Fernando García de la Cruz, Pablo Zinemanas, Emilio Molina, Martín Rocamora

The proliferation of AI-generated music in broadcast media raises concerns about transparency and fair compensation, but reliable detection under real broadcast conditions remains unresolved. Existing studies report substantial performance degradation in this domain, yet their evaluations are limited to synthetic broadcast data. To address this gap, we introduce BAMM (Broadcast AI-Music Monitoring), a 40-hour dataset of real-world television recordings containing AI-generated and human-made music. We compare clean-trained and broadcast-trained CNN variants across three progressively more challenging scenarios: Clean Foreground Music (CFM), Synthetic TV Broadcast (STB), and Real TV Broadcast (RTB). Both models achieve near-perfect performance on CFM but degrade substantially under synthetic broadcast conditions. Broadcast-oriented training improves robustness compared with clean training, although performance remains limited. On RTB, evaluated using BAMM, both models degrade further and show substantial score overlap between AI-generated and human-made music. These results expose a critical domain gap and show that current training approaches on CNN-based detectors remain insufficient for reliable AI-generated music detection in broadcast monitoring.

arXiv

Towards Assurance Closure in AI-Native Large-Scale Agile Software Development

Ricardo Britto

The AI-Native Manifesto envisions large-scale agile software development in which humans increasingly govern intent, risk, and exceptions while agents execute more of the engineering process. Realizing that end-state requires more than better code generation: it requires assurance closure, meaning that the system can establish what must be true, determine and obtain appropriate evidence, judge the credibility of that evidence, preserve its validity through change, and use the resulting uncertainty to bound agent authority. Existing work already provides many of the necessary mechanisms across formal methods, testing, simulation, assurance cases, digital twins, and runtime assurance. We identify six residual gaps in making the surrounding assurance reasoning sufficiently machine-operable, propose a high-level architecture with six corresponding capabilities built on a shared semantic assurance layer, and formulate four research questions to turn that architecture into dependable, human-on-the-loop, AI-native R&D.

arXiv

How Much AI Is in This Track? Quantifying the Proportion of AI-Generated Stems in Hybrid Music Mixtures

Fernando Garcia de la Cruz, David López-Ayala, Pablo Zinemanas, Emilio Molina, Martín Rocamora

AI-generated music is increasingly used at the stem level, with producers integrating synthetic drums, basslines, or vocals alongside human-performed instruments. However, current AI music detection systems are binary, treating tracks as either fully AI or fully human. In this paper, we reformulate AI music detection as a regression problem on a continuous AI energy ratio, alpha in [0, 1]. We propose a methodology that leverages a multi-track music dataset to assemble mixtures of human-performed and AI-reconstructed stems (obtained using a neural audio codec) with known proportions of each content type. Using this approach, we first show that a CNN-based model trained on fully AI-generated or human-performed tracks, which achieves >99% accuracy as a binary detector, when faced with mixed content, yields an output that rises with the AI stems' energy contribution, acting as a noisy and miscalibrated estimator. Our analysis of the influence of different stems shows that detection sensitivity depends on the instrument and reflects its frequency content: drums and guitar carry strong codec-artifact signatures, while vocals and bass are less detectable. Based on these insights, we train a similar CNN-based model for regression of alpha, achieving MAE = 0.076 and R^2 = 0.85 on held-out mixtures from the same pipeline. These results suggest that the regression formulation is an initial promising step towards AI-music detection in realistic music production workflows.

arXiv

A Finite E-Group of Nilpotency Class Three

Xinan Dai, Wenhao Deng, Yidong Shi, Tailin Wu, Yuchen Yang

A group is an E-group if every element commutes with each of its endomorphic images. Caranti asked whether a finite E-group can have nilpotency class three. We prove that the $3$-group of order $3^{84}$ introduced by Abdollahi, Faghihi, and Mohammadi Hassanabadi, and later shown by Abdollahi, Faghihi, Linton, and O'Brien to have the corresponding automorphism property, is an E-group. Let $P$ denote this group and put $V=P/Φ(P)\cong \mathbb{F}_3^9$. The nine power relations of $P$ determine a linear map $q:V\longrightarrowΛ^2 V$. We prove that $q$ has no nonzero proper subspace $U$ satisfying $q(U)\subseteqΛ^2 U$. Since the image induced by any endomorphism of $P$ on $V$ has precisely this closure property, every endomorphism acts on $V$ either invertibly or trivially. The invertible case is the known A-group case. In the trivial case the image first lies in $Φ(P)=P'$, and the power relations then force it into $Ω_1(P')=Z(P)$. Thus every element commutes with every endomorphic image. The tensor rigidity is reduced to an exact finite calculation on the $9841$ points of $\mathrm{PG}(8,3)$.

arXiv

Reading Copom's Tone: A Weighted LLM Framework for Hawkish-Dovish Sentiment, Forward Guidance, and Uncertainty

Gabriel de Macedo Santos

This paper documents an applied natural-language-processing framework for measuring the tone of Brazilian Monetary Policy Committee (Copom) statements. The project is explicitly inspired by iSent, Itaú's Central Bank sentiment classifier, particularly its sentence-level division of official communication into hawkish, dovish, neutral, and out-of-context classes. The implementation extends that idea in three directions. First, an LLM identifies short hawkish and dovish expressions and assigns each a 0-to-1 intensity weight. Second, the document index combines sentence counts with document-specific average signal intensities, producing a bounded score from -1 to 1. Third, a separate full-document layer measures forward-guidance direction, guidance explicitness, uncertainty level, and change in uncertainty. The empirical sample is restricted to communications dated August 2016 or later and contains 80 statements and 1,498 classified sentences from August 31, 2016 through August 5, 2026. Across this sample, 33.3% of sentences are hawkish, 18.0% dovish, 42.1% neutral, and 6.5% out of context. The average document score is +0.107, while the most hawkish reading is +0.570 in August 2021. The latest statement, dated August 5, 2026, scores +0.232, with eight hawkish, two dovish, and nine neutral sentences. Its structural overlay is more nuanced: guidance is directionally ambiguous but partly explicit, while uncertainty is classified as central and higher than at the prior meeting. Tone and the guidance-direction score have a contemporaneous Pearson correlation of 0.719. These are descriptive outputs, not a validated forecast of Selic decisions or DI returns. The main contribution is therefore methodological: a transparent, incremental, auditable system that separates rhetorical tone from policy guidance and uncertainty.

arXiv

From probability to causality in probabilistic logic programming

Zora Wurm, Kilian Rückschloß, Felix Weitkämper

Probabilistic logic programming is a formalism of statistical relational artificial intelligence that supports causal queries, including interventions from outside the system. When the structure of a probabilistic logic program is learned from data, however, only probabilistic information is used, and a single probability distribution may be compatible with several causal orders. This leads to ambiguity in interventional reasoning, raising the question of when the causal order is uniquely determined by the distribution. Exploiting the relationship between acyclic probabilistic logic programs and Bayesian networks, we derive conditions under which the probabilistic information encoded in a program determines a unique causal order. We also incorporate constraints arising from relational structure by taking into account prescribed sets of causal symmetries induced by the underlying relational vocabulary. The result is a method for verifying when a learned probabilistic logic program supports well-defined intervention semantics.

arXiv

Beyond the Black Box: Interpretable Models of Human Randomisation Failures

Ngoc Linh Dao

Mixed strategy equilibrium predicts i.i.d play: past actions should not help predict future decisions. Human players, however, systematically depart from this benchmark, and in O'Neill's zero sum card game, these departures can be predicted by black box sequence models such as LSTMs. This paper asks whether that predictive power can be achieved by transparent alternatives that also reveal the behavioural structure behind it. Using 84,060 decisions from 2,802 pairs, the analysis first benchmarks naive and behavioral models against interpretable machine learning and deep learning models, then evaluates the modified EWA specifications of prior work against these benchmarks and uses the LASSO diagnostics to motivate a further nested frequency tracking extension. The results show that repeat or avoid behavior, especially players' management of their own recent action histories, accounts for most of the interpretable and strategically exploitable signal, while frequency tracking adds little out of sample.

arXiv

Toward a Causal Data Management Ecosystem for Decision Making and Agentic AI

Dazhuo Qiu, Yingli Zhou, Amedeo Pachera, Angela Bonifati, Andrea Mauri

Modern AI is no longer a single model but an ecosystem: classical ML predictors, deep and multimodal models, large language models, and agents, each trained and tuned over different data sources and each producing outputs at scale that become inputs to the others. Operating such an ecosystem is fundamentally a data integration problem - the knowledge it depends on is fragmented across dozens of heterogeneous, independently governed sources that must be reconciled and continually maintained. Yet integration alone is not enough. The predictions these systems make are shaped by many interacting factors, and the events, decisions, and variables that drive an outcome are routinely entangled with the ones that merely accompany it; treated as a basis for action, such correlational signals invite confounded decisions. This becomes acute once agents act autonomously: to be trustworthy and reliable, an agent must anticipate the consequences of its actions, not merely extrapolate from what has co-occurred before. Causal reasoning is what closes this gap, distinguishing the drivers of an outcome from its correlates, and enabling prescriptive and counterfactual analysis over the ecosystem's data. We therefore argue that the integrated ecosystem needs an explicit causal layer, and we propose to build it as a shared, persistent, queryable Causal World System (CWS).

arXiv

Authoring and Management of Transparent Research Integrity Assessments of Randomised Clinical Trial Publications Using LLM-assisted Tools and Provenance Knowledge Graphs

Milan Markovic, Goutham Indukuri, Somayajulu Sripada, Colby J. Vorland, Jack Wilkinson, Clare Robertson, Mark Bolland, Andrew Grey, Miriam Brazzelli, Alison Avenell

Systematic reviews of Randomised Controlled Trials (RCTs) are routinely used as evidence for clinical care guidelines. Such evidence has to meet high research integrity standards to prevent low quality or false research outputs influencing the clinical care. However, assessing research integrity of published RCTs is a complex process requiring manual effort, and potentially resulting in diverse opinions of the human assessors. This paper describes INSPECT-AI, an LLM-based interactive tool that assists human reviewers with research integrity assessments of published RCTs based on the community approved INSPECT-SR framework, and the Research Integrity Provenance and Evidence ontology (RIPE-O) for documenting the provenance of the assessment process. In addition, we present the Research Integrity Provenance and Evidence knowledge graph (RIPE-KG), an initial set of 140 expert research integrity assessments of 95 RCT publications generated by INSPECT-AI and described using RIPE-O.

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