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arXiv

SemiSAM-O1: Pushing the Boundary of Annotation-Efficient Medical Image Segmentation with Generalist Knowledge Fusion

Yichi Zhang, Le Xue, Bichun Xu, Judong Luo, Zhigang Wu, Yu Fu, Zixin Hu, Yuan Cheng, Yuan Qi

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to extremely limited annotation scenarios, they fail to maintain robust competitive performance in complex imaging modalities. In this paper, we propose SemiSAM-O1, an annotation-efficient framework using only one annotated template case for segmentation. SemiSAM-O1 extends the specialist-generalist collaborative learning framework to the extreme one-label setting by fully exploiting the foundation model's feature representation capability beyond its prompting interface. SemiSAM-O1 operates in two stages. In the first stage, the foundation model's encoder extracts dense features from all volumes, and class prototypes derived from the single annotated template are propagated to the unlabeled pool via feature similarity to produce coarse initial pseudo-labels. In the second stage, an iterative training-and-refinement loop progressively improves both the segmentation model and the pseudo-labels over multiple rounds, where each round trains the model from scratch on current pseudo-labels and generates updated predictions with voxel-wise uncertainty estimates. An uncertainty-guided refinement step further leverages the foundation model's global feature space to correct high-uncertainty regions by aggregating labels from their most similar confident neighbors, establishing a virtuous cycle of mutual improvement. Extensive experiments on a wide range of segmentation tasks across different modalities and anatomical targets demonstrate that SemiSAM-O1 significantly narrows the performance gap between one-label semi-supervised learning and full supervision, while significantly reducing the computational overhead of online foundation model inference.

arXiv

NavTrust: Benchmarking Trustworthiness for Embodied Navigation

Huaide Jiang, Yash Chaudhary, Yuping Wang, Zehao Wang, Raghav Sharma, Manan Mehta, Yang Zhou, Lichao Sun, Zhiwen Fan, Zhengzhong Tu, Jiachen Li

There are two major categories of embodied navigation: Vision-Language Navigation (VLN), where agents navigate by following natural language instructions; and Object-Goal Navigation (OGN), where agents navigate to a specified target object. However, existing work primarily evaluates model performance under nominal conditions, overlooking the potential corruptions that arise in real-world settings. To address this gap, we present NavTrust, a unified benchmark that systematically corrupts input modalities, including RGB, depth, and instructions, in realistic scenarios and evaluates their impact on navigation performance. To our best knowledge, NavTrust is the first benchmark that exposes embodied navigation agents to diverse RGB-Depth corruptions and instruction variations in a unified framework. Our extensive evaluation of seven state-of-the-art approaches reveals substantial performance degradation under realistic corruptions, which highlights critical robustness gaps and provides a roadmap toward more trustworthy embodied navigation systems. Furthermore, we systematically evaluate four distinct mitigation strategies to enhance robustness against RGB-Depth and instruction corruptions. Our base models include Uni-NaVid and ETPNav. We deployed them on a real mobile robot and observed improved robustness to corruptions. The project website is: https://navtrust.github.io/.

arXiv

nnMIL: A generalizable multiple instance learning framework for computational pathology

Xiangde Luo, Jinxi Xiang, Yuanfeng Ji, Ruijiang Li

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images (WSIs), but current approaches for aggregating these features into slide-level predictions remain constrained by design limitations that hinder generalizability and reliability. Here we present nnMIL, a simple yet broadly applicable multiple-instance learning framework that connects patch-level foundation models to robust slide-level clinical prediction. nnMIL introduces random sampling at both the patch and feature levels, enabling large-batch optimization, task-aware sampling strategies, and efficient and scalable training across datasets and model architectures. A lightweight aggregator performs sliding-window inference to generate ensemble slide-level predictions and supports principled uncertainty estimation. Across 40,000 WSIs encompassing 35 clinical tasks and four pathology foundation models, nnMIL consistently outperformed existing MIL methods for disease diagnosis, histologic subtyping, molecular biomarker detection, and pan-cancer prognosis prediction. It further demonstrated strong cross-model generalization, reliable uncertainty quantification, and robust survival stratification in multiple external cohorts. In conclusion, nnMIL offers a practical and generalizable solution for translating pathology foundation models into clinically meaningful predictions, advancing the development and deployment of reliable AI systems in real-world settings.

arXiv

Dynamic Object Masks as Goal Representations for Visual Goal-Conditioned Reinforcement Learning

Fahim Shahriar, Cheryl Wang, Alireza Azimi, Gautham Vasan, Hany Hamed, Abhishek Naik, A. Rupam Mahmood, Colin Bellinger

Goal-conditioned reinforcement learning (GCRL) offers a unified way to pursue diverse tasks, yet most existing methods rely on state- or position-based goal representations that are unavailable in real-world robotics. Robots operating in warehouses, agriculture, or laboratory environments rarely have access to privileged goal states, object positions, or future observations, limiting the practicality of current GCRL approaches. We propose a dynamic mask-based goal representation that provides simple, object-agnostic visual cues for vision-based navigation and manipulation. At each timestep, an image-based goal detector produces a goal mask using standard image processing, task-specific object recognizers, or pretrained detectors such as Detic or Grounding DINO. These masks specify the spatial target without requiring privileged goal states, enabling broad applicability and strong generalization to unseen objects. Our method improves stability and sample efficiency in GCRL, achieving a 99% success rate in reaching both training and novel objects with Franka and UR10e robotic arms and faster learning in simulated navigation. We further demonstrate learning from scratch and sim-to-real transfer on both robotic arms, highlighting the effectiveness of our approach for real-world RL tasks. Our code is available at https://github.com/fahimfss/GCRL.

arXiv

APTx Neuron: A Unified Trainable Neuron Architecture Integrating Activation and Computation

Ravin Kumar

We propose the APTx Neuron, a novel, unified neural computation unit that integrates non-linear activation and linear transformation into a single trainable expression. The APTx Neuron is derived from the APTx activation function, thereby eliminating the need for separate activation layers and making the architecture both optimization-efficient and elegant. The proposed neuron follows the functional form $y = \sum_{i=1}^{n} ((α_i + \tanh(β_i x_i)) \cdot γ_i x_i) + δ$, where all parameters $α_i$, $β_i$, $γ_i$, and $δ$ are trainable. We validate our APTx Neuron-based architecture on the MNIST dataset, achieving up to $96.69\%$ test accuracy within 11 epochs using approximately 332K trainable parameters. The results highlight the superior expressiveness and training efficiency of the APTx Neuron compared to traditional neurons, pointing toward a new paradigm in unified neuron design and the architectures built upon it. Source code is available at https://github.com/mr-ravin/aptx_neuron.

arXiv

CoCo-IR: Contextual Composed Image Retrieval

Shengcao Cao, Tanmaya Shekhar Dabral, Zhongli Ding, Madhuri Shanbhogue, Kaifeng Chen, Zhe Li, Mojtaba Seyedhosseini, Yu-Xiong Wang, Liang-Yan Gui

Current instruction-based image retrieval systems are powerful but limited to single-turn interactions, failing to capture the iterative nature of complex, real-world visual searches. To overcome this limitation, we introduce Contextual Composed Image Retrieval (CoCo-IR), a novel task that enables users to progressively refine search results through interactions. We address this new task by proposing a new model based on a Large Multimodal Model (LMM) that functions as a context-aware reasoner for CoCo-IR. Our model interprets the entire interaction history to generate Transformable Image Embeddings (TIE) that evolve across turns. To fuel the model training without expensive human annotations, we develop a fully autonomous, scalable data engine that leverages LMMs to generate high-quality contextual retrieval data, and uses model-guided verification to mine challenging hard negatives. Extensive experiments demonstrate that our approach establishes new state-of-the-art performance: We achieve 39.4 mAP@5 on the challenging single-turn benchmark CIRCO; furthermore, on our new CoCo-IR benchmark, our model maintains robust performance with 44.1 R@1 on 4-turn dialogues, dramatically outperforming existing methods (28.2 4-turn R@1) that fail to handle multi-turn context. Project page: https://CoCo-IR.github.io.

arXiv

Predicting Brain Morphometry with MT-GNN: Mesh Evolution in Continuous Time with Graph-Based Metric Tensor Embeddings

Hao Ding, Daniel Semchin, Paul M. Thompson, Boris Gutman

Predicting how a subcortical structure's shape will evolve from a few prior scans could support prognosis and clinical-trial enrichment. Existing longitudinal mesh predictors either extrapolate shape trajectories via high-dimensional embeddings or regress vertex deformations directly. We instead predict the surface's intrinsic geometry in continuous time: a single per-structure graph network predicts the future per-vertex first fundamental form (metric tensor) for an arbitrary causal multiple-visit history and an arbitrary prediction horizon, conditioned on a Fourier encoding of the lead time. The predicted metric is decoded into a surface by a differentiable As-Rigid-As-Possible solver, and the model is trained end-to-end on the rigid-aligned vertex error. Training through the reconstruction keeps the decoded prediction a valid surface and consistently improves it. On 14 subcortical structures from the ADNI dataset, the proposed mesh evolution model (MT-GNN) predicts best among the evaluated methods at every horizon ($-2.29\%$ mean vertex error vs. the temporal mean, $p{=}6.1{\times}10^{-5}$, beating it on 14/14 structures), ahead of geodesic shape regression (DCM, $-0.19\%$) and a mesh transformer (TransforMesh, $-0.45\%$; $p{=}1.2{\times}10^{-4}$), with the lead widening as the horizon grows.

arXiv

Robust and Efficient Motion Reasoning for Privacy-Aware Classroom Incident Recognition

Paritosh Parmar, Landy Lan, Hong Yang, Chen Yi, Chiat Pin Tay

Can computer vision help make classrooms safer? In this pilot study, we investigate privacy-aware and computationally efficient classroom incident recognition from CCTV-style observations. This setting remains underexplored, with limited benchmarks and few methods designed for the privacy, efficiency, and generalization demands of real-world deployment. We introduce a novel hybrid benchmark combining generative CCTV-style videos with real-world classroom pose data, and propose a lightweight, but robust motion-reasoning framework motivated by the observation that many incidents differ more in motion direction, speed, acceleration, and intensity than in pose alone. To that end, our method first constructs hierarchical kinematic representations of human actions. Our method then distills hierarchical, multi-order kinematic reasoning from a large teacher into a much smaller single-order student, enabling efficient per-person inference while preserving expressive motion understanding. Experiments show that our model outperforms substantially larger baselines at less than one-tenth of their computational cost, while also demonstrating stronger out-of-domain motion reasoning and zero-shot synthetic-to-real generalization. We will publicly release the benchmark, codebase, and supporting tools to facilitate further research in privacy-aware classroom safety.

arXiv

HexMIL: Hierarchical Attention MIL for Ante-Hoc Explainable Detection of AI-Manipulated CT Volumes

Orazio Pontorno, Luca Guarnera, Zahid Akhtar, Sebastiano Battiato

The emergence of medical deepfakes, i.e., medical images manipulated by deep generative models, poses a significant threat to clinical workflows. However, existing detectors suffer from two critical limitations: poor generalization to unseen generative architectures for manipulation detection and lack of interpretability. In this context, we present HexMIL (Hierarchical EXplainable Multiple Instance Learning), a mask-free medical deepfake detector that simultaneously addresses both limitations using only binary volume-level supervision. HexMIL decomposes each CT volume into a two-level hierarchy of patches and slices, aggregated via independent Gated Attention modules whose weights are directly combined into a full-resolution 3D attention volume that localizes the manipulated sub-region without any pixel-level annotation. Unlike post-hoc methods such as Grad-CAM, HexMIL's attention weights constitute the exact forward computation driving the classification decision, providing ante-hoc and structurally faithful spatial attribution. We evaluate HexMIL on M3DSynth and CT-GAN datasets under a rigorous cross-generator generalization protocol, training on a single generative architecture and testing on unseen ones. HexMIL outperforms all baselines by $+9.1$ AUC and $+9.4$ F1 in out-of-domain classification, and achieves the best average IoU and Pointing Game score in localization. Project page: opontorno.github.io/hexmil.

arXiv

Lesion Detection in CT with Frozen Self-Distilled Features: SALT, a Spatially Adaptive Label-Guided Temperature

Mahmut S. Gokmen, Evan W. Damron, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner

Self-supervised pretraining objectives are spatially uniform: the teacher temperature and the per-patch loss weight are identical everywhere in the image, so a lesion a few patches wide contributes no more to the training signal than the surrounding parenchyma. Prior work biases the views toward annotated regions, which changes what the model sees but adds no pressure on the objective. We instead condition the targets of self-distillation, a method we call SALT (Spatially Adaptive Label-guided Temperature). Weak, box-derived labels, available only during pretraining, define a compact region on the encoder's patch grid, inside which the teacher's softmax temperature is sharpened and the masked-patch loss is up-weighted. The objectives, the masking policy and the centering statistics are otherwise unchanged, and at every downstream use the encoder is a plain feature extractor with no labels and no conditioning. We evaluate by freezing the encoder and training only a lightweight multi-depth CenterNet-style head, detecting lesions in 3D on four CT cohorts, and we isolate the mechanism against a backbone identical in architecture, pretraining data, schedule and label-guided cropping but with no target conditioning. We report patch-level separability, 3D detection stratified by cohort and by lesion size, box quality, and a detector-free probe in which a single frozen patch embedding re-identifies a lesion in a follow-up scan without registration, masks or fine-tuning. Because the conditioning is expressed through a spatial indicator rather than through label semantics, the formulation admits any weak spatial annotation; we instantiate and validate it for lesions.

arXiv

Bag-of-Visual-Words for Spatial Mapping of Lung Adenocarcinoma Growth Patterns

Darya Ardan, Valentin Oreiller, Henning Müller

Spatial mapping of lung adenocarcinoma (LUAD) growth patterns across whole slide images (WSIs) requires resolving architectural context at the region level, yet existing methods operate at the individual tile level and produce generic morphological clusters rather than clinically defined pattern maps. We propose a weakly supervised Bag-of-Visual-Words (BoVW) pipeline that learns a visual vocabulary from frozen foundation model embeddings extracted from a small set of annotated regions of interest (ROIs). Pattern prototypes are constructed as mean BoVW histograms of same-label ROIs and used for nearest-prototype classification of sliding-window regions under Jensen--Shannon divergence. The resulting predictions are projected onto the WSI tile grid to produce interpretable spatial pattern maps. We evaluate the method on 87 CPTAC-LUAD patients using three foundation model encoders and multiple vocabulary sizes on two clinically motivated tasks. For tumour/healthy classification, the best configuration achieves a balanced accuracy of $0.974$ with H-Optimus-1, approaching the $0.987$ obtained by a supervised SVM trained on mean-pooled WSI embeddings. For binary histologic grade classification, the BoVW pipeline achieves higher balanced accuracy than the supervised baseline for all encoders, suggesting that ROI-level pattern decomposition preserves grade-relevant heterogeneity that is attenuated by global mean pooling.

arXiv

HelloWorld: Enabling Socially Interactive Characters in Video World Models

Liangyang Ouyang, Ruicong Liu, Xuangeng Chu, Kaipeng Zhang, Yoichi Sato

Despite the remarkable recent progress of video world models, social interaction between users and the characters within these worlds remains unsupported. To fill this gap, we present HelloWorld, a video world model that enables social interaction with in-world characters. With a single button press, users can prompt the on-screen character to respond toward the camera, e.g., turning to the viewer, waving, nodding, or speaking a short greeting. To make these interactions natural, we propose a self-distillation pipeline that finetunes the video generation model on data synthesized by itself. Each synthesized clip contains both social interactions and camera motion, allowing the model to learn camera-pose conditioning without degrading interaction quality. At inference, we further introduce a training-free module that determines when the interaction occurs. Upon a button press, it modulates the cross-attention masks of the DiT so that the interaction-related text prompt attends only to the frames within the press window, temporally localizing the character's response. We further build HelloWorldBench, a 400-sample benchmark with three social interaction metrics alongside three conventional metrics, for evaluation. Experiments demonstrate that HelloWorld surpasses a variety of baselines in interaction quality, while maintaining state-of-the-art picture aesthetics and camera-pose following. Project page: https://github.com/AlayaLab/HelloWorld

arXiv

VQ-VAD: Vector-quantized Motion Representation Learning for Human-centric Video Anomaly Detection

Narges Rashvand, Ghazal Alinezhad Noghre, Shanle Yao, Gabriel Maldonado, Hamed Tabkhi

Video Anomaly Detection (VAD) is inherently challenging due to the scarcity of anomalies and the large visual variability in surveillance footage, including changes in lighting, viewpoint, and human appearance. To mitigate visual noise and address privacy concerns, recent work has shifted to pose-based VAD, which focuses on motion dynamics rather than raw video data. However, existing pose-based approaches model human behavior in continuous latent spaces, limiting their ability to learn compact motion patterns necessary for robust behavior analysis. We address this by proposing Vector-Quantized Video Anomaly Detection (VQ-VAD), a novel human-centric anomaly detection framework that learns discrete motion representations. VQ-VAD adapts Vector-Quantized GAN (VQ-GAN), originally developed for image generation, to operate on keypoint sequences and construct a motion codebook of normal behavior. Trained exclusively on normal motion sequences, VQ-VAD detects anomalies by identifying high reconstruction errors when an observed motion sequence cannot be mapped to the learned codebook. We conduct extensive experiments across three complementary evaluation settings, including in-domain, cross-domain, and cross-dataset generalization, on four anomaly detection benchmarks. VQ-VAD achieves strong in-domain accuracy (81.83% on HR-SHT [15]), effective cross-domain transfer from CMU Panoptic [14] (76.69% on HR-SHT [15] without retraining), and competitive cross-dataset robustness. The code base for this work is available at https://github.com/TeCSAR-UNCC/VQ-VAD.

arXiv

Beyond Reprojection Error: Camera Calibration with 3D Targets

Dennis Ruppel, Hasan Kutlu, Kai A. Neumann, Martin Knuth, Pedro Santos, Andreas Weinmann, Arjan Kuijper

In 3D reconstruction, camera calibration is an essential element for achieving high fidelity and accuracy of the reconstructed geometry. While existing approaches rely upon 2D planar calibration, this work proposes a framework tailored for 3D reconstruction that is based on predicting scene rays, which adds flexibility to the reconstruction pipeline and enables the use of recent advances in camera models. Novel metrics, reconstruction and intersection error, derived from predicted scene rays are employed in combination with a bootstrapping procedure that statistically evaluates different calibration objects and calibration pipelines for both intrinsic and extrinsic camera parameters. The results show that the generalized distortion model more faithfully captures physical camera effects and yields an improvement in calibration accuracy. Reprojection error is shown to be a potentially misleading indicator of 3D accuracy, and the proposed ray-based metrics provide a more holistic assessment. An icosahedron calibration target is designed to enrich calibration information for 3D reconstruction together with a ring-feature-based detector. The icosahedral target yields approximately 40% lower mean intersection and more stable calibration across bootstrap trials on synthetic data, while real-data performance demands very tight fabrication tolerances.

arXiv

MarsCast: Transfer Learning of AI Weather Foundation Models to Planetary Atmospheres

M. L. Carroll, J. Li, S. D. Guzewich, G. Villanueva, J. A. Caraballo-Vega, M. J. Frost

We investigate the transferability of Earth weather foundation models to planetary atmospheres by adapting the GraphCast graph neural weather forecasting model to Mars. While GraphCast achieves state-of-the-art performance for terrestrial forecasting, its applicability to non-Earth environments remains unexplored. Using the Mars Climate Database (MCD), which provides global atmospheric fields across vertical altitude levels (similar to Earth pressure levels), we evaluate zero-shot and fine-tuned GraphCast predictions of Martian temperature and wind fields. Zero-shot forecasts produce a surprisingly accurate depiction of current conditions but fail to reproduce diurnal variability and rapidly decay toward climatological mean states. To address this limitation, we fine-tune GraphCast using MCD variables and top-of-atmosphere solar radiation forcing while holding humidity constant. Fine-tuning enables rapid learning of Martian thermal variability. Within as few as 10 training epochs, the model begins to capture the diurnal cycle and forecasts up to 10 days reproduce seasonal and vertical temperature structure. Prediction quality improves with training sample size and exhibits sensitivity to seasonal initialization. These results demonstrate that Earth-trained AI weather models can be adapted to simulate Martian atmospheric dynamics, providing a pathway toward rapid planetary weather prediction to support mission operations, dust storm risk mitigation, and future human exploration.

arXiv

OmniEdit-Bench: A Comprehensive Benchmark for Instruction-based Video Editing

Chenxuan Miao, Yutong Feng, Yi Lu, Yunfeng Yan, Donglian Qi, Shiwei Zhang, Yu Liu, Xi Chen, Hengshuang Zhao

Instruction-based video editing (IVE) is an emerging field with broad applications, yet evaluating editing models remains challenging. Existing benchmarks suffer from two major limitations: limited task coverage inherited from image editing, which overlooks video-specific dimensions, and inadequate metrics that fail to measure instruction fidelity, allowing incorrect edits to receive high scores due to strong visual priors from the original video. To address these issues, we introduce a comprehensive and structured benchmark for IVE. Our benchmark decomposes editing tasks into multiple video-specific dimensions, including spatial, temporal, audio, and reference-based editing, extending beyond conventional frame-level evaluation. It also distinguishes explicit and implicit instructions and incorporates reasoning-based scenarios to better reflect real-world requirements. Furthermore, we propose an evaluation framework that assesses editing quality from four complementary dimensions: accuracy, preservation, realism, and consistency, using both human judgments and state-of-the-art vision-language models. To emphasize instruction fidelity, we introduce an accuracy-aware penalty mechanism that conditions other scores on accuracy, preventing visually plausible but incorrect edits from receiving inflated evaluations. Extensive experiments on representative open-source and commercial models show that current IVE models remain far from satisfactory. OmniEdit-Bench provides a comprehensive and reliable testbed for evaluating instruction-based video editing and offers insights into future research directions.

arXiv

Promptable Animal Pose Tracking Across Species

Le Li, Daniela Ivanova, Nicolas Pugeault

Animal pose estimation and tracking is important for wildlife monitoring and conservation research, and with limited expert time for labelling automated approaches are imperative. While human pose estimation and tracking has seen rapid progress thanks to large annotated datasets, animal pose remain challenging, due to large morphological and behavioural differences between species and limited annotated data. Existing approaches either optimise generic keypoint localisation from annotated datasets (such as APTv2) with poor generalisation, or track custom keypoints using visual tracking, at the cost of performance. In this paper, we demonstrate that vision foundation models trained on large datasets can be used effectively to track animal pose with limited labelled data. We propose two models, one unsupervised and the other supervised, to track user-selected keypoints in videos. The supervised approach delivers superior tracking accuracy by employing a keypoint prompt encoder to explicitly inject structural priors from a reference frame into feature matching. In parallel, the unsupervised route provides strong cross-species robustness by leveraging diverse foundation-model features for training-free correspondence matching. Extensive evaluation on challenging animal video benchmarks APTv2 and TigDog demonstrates that our framework achieves strong performance while maintaining an effective balance between accuracy and generalisation, offering a practical solution for real-world animal behaviour analysis and conservation applications.

arXiv

ContextMaster: Interactive Multi-Shot Video Creation via Fixed-Budget Sparse Context Routing

Xu Guo, Zhengxuan Wei, Xinghui Li, Hanzhuo Huang, Xinyu Liu, Xiangyang Luo, Min Wei, Yiran Zhu, Qiulin Wang, Yulong Xu, Xintao Wang, Pengfei Wan, Qi Fan, Xiangwang Hou

Recent video models increasingly support generation, reference conditioning, and editing within a single model, yet typically expose them as separate operations over fixed inputs. Practical creation unfolds across multiple shots, requiring one model to generate from text, follow a reference, or edit source footage while maintaining shared history. We formalize this setting as interactive multi-shot video creation (IMVC) and introduce ContextMaster, a unified model with a role-aware context representation for these operations. An interactive model must retain access to an expanding history without allowing the context read cost at each denoising step to grow. ContextMaster combines reusable clean context states with fixed budget sparse context routing and uses ConstraintSink to keep task constraints visible. To address the dual challenges of sparse context access and inference with few denoising steps, we propose a two-stage privileged context distillation framework, which transfers full context behavior from a dense teacher through consistency distillation and then refines deployment rollouts with distribution matching. Experiments on the three primitive tasks demonstrate improved task fulfillment and consistency across shots over specialized baselines. User studies further validate flexibly composed workflows, while the model reaches 16 FPS on a single GPU.

arXiv

Enhancing Low Back Pain Assessment with Diffusion Models for Lumbar Spine MRI Segmentation

Maria Monzon, Thomas Iff, Ender Konukoglu, Catherine R. Jutzeler

This study introduces a diffusion-based framework for robust and accurate semantic segmentation of lumbar spine MRI scans from patients with low back pain (LBP), regardless of whether the scans are T1- or T2-weighted. We compared with advanced models for segmenting vertebrae, intervertebral discs (IVDs), and spinal canal using the SPIDER dataset. The results showed that SpineSegDiff achieved a segmentation performance comparable to that of the state-of-the-art non-diffusion nnUnet, particularly in improving the identification of degenerated IVDs. In addition, the uncertainty maps generated by our model provide valuable insights for clinical review, enhancing the robustness and reliability of the segmentation results. The potential of diffusion models to enhance the diagnosis and management of LBP through more precise analysis of pathological spine MRI is underscored by our findings.

arXiv

Visual Representation Matters: Exploiting Temporal Differences in Video-to-Audio Generation

Zehua Chen, Junyou Wang, Yuxuan Jiang, Zhenying Fang, Yusheng Dai, Jianfei Chen, Ziwei Liu, Jun Zhu

Video-to-audio (V2A) generation extends image-to-audio generation (I2A) by introducing consecutive frames that provide essential temporal cues for audio synthesis. However, existing conditional diffusion-based V2A methods typically enhance visual conditioning with additional audio-visual supervision, acoustic structure prediction, or reasoning from large multimodal models, requiring extra networks or strong inductive biases. Inspired by recent advances in visual representation learning, we introduce TD-V2A, which leverages temporal differences (TD) as the key representation that distinguishes V2A from I2A, enriching visual conditioning with minimal architectural modification. We first investigate TD at both the frame and feature levels to identify the most effective representation level at which TD complements visual representations. Based on these findings, we develop a hierarchically continual learning strategy and an annealed temporal differences guidance method to progressively learn and exploit TD information during diffusion training and sampling process, respectively. Extensive experiments on benchmark datasets demonstrate that effectively exploiting TD through our proposed framework significantly improves end-to-end V2A generation quality, even outperforming dedicated V2A representations such as contrastive audio-visual pretraining.

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