A Parallel Network for LRCT Segmentation and Uncertainty Mitigation with Fuzzy Sets

Abstract

Accurate segmentation of airways in Low-Resolution CT (LRCT) scans is vital for diagnostics in scenarios such as reduced radiation exposure, emergency response, or limited resources. Yet manual annotation is labor-intensive and prone to variability, while existing automated methods often fail to capture small airway branches in lower-resolution 3D data. To address this, we introduce FuzzySR, a parallel framework that merges super-resolution (SR) and segmentation. By concurrently producing high-resolution reconstructions and precise airway masks, it enhances anatomic fidelity and captures delicate bronchi. FuzzySR employs a deep fuzzy set mechanism, leveraging learnable t-distribution and triangular membership functions via cross-attention. Through parameters μ, σ, and d_f, it preserves uncertain features and mitigates boundary noise. Extensive evaluations on lung cancer, COVID-19, and pulmonary fibrosis datasets confirm FuzzySR’s superior segmentation accuracy on LRCT, surpassing even high-resolution baselines. By uniting fuzzy-logic-driven uncertainty handling with SR-based resolution enhancement, FuzzySR effectively bridges the gap for robust airway delineation from LRCT data.