NeurIPS 2026 Papers

Conference on Neural Information Processing Systems

Decision breakdown

6,437papers

Counted from the official paper list; may differ slightly from the number the conference announced.

  • Oral
    991.5%
  • Spotlight
    2403.7%
  • Poster
    6,09894.7%

Browse all papers

Diffusion Meta-Prompting and Steering for Generalizable Foundation Model Adaptation

Deepak Sridhar, Yi Li, Kartikeya Bhardwaj, Shuangjun Liu, Taotao Jing, Yuan Li, Shuai Zhang, Jiancheng Lyu, Dashan Gao, Nuno Vasconcelos

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Prompt learning is a popular parameter-efficient method for adapting foundation models, but learned prompts are typically task-specific and fail to generalize to new classes, domains, or compositions of tasks. In this paper, we introduce a $\textbf{Diffusion Meta-Prompt (DMP)}$ model , a framework that models the distribution of learned prompts using diffusion models. DMP is trained only on a repository of previously learned prompts to synthesize new prompts conditioned on natural language task descriptions, without access to the task data. To improve the sampling stability, we introduce a test-time steering strategy for DMP, which uses the best training-selected prompt in the repository as a latent anchor during diffusion sampling, without retraining the DMP or accessing test classes. DMP improves generalization across classification, retrieval and text-to-image generation tasks, supports concept composition and negative prompting without explicit training. It reduces storage and inference costs by over 90% compared to prompt retrieval methods. For composite classification, DMP achieves upto $\textbf{2.0}$% average gain over prior meta-learning methods across 55 pairs of datasets with gains as high as $\textbf{8.5}$% on specific pairs such as Eurosat and Flowers. DMP also enhances cross-task generalization with $\sim$$\textbf{2-9}$% improvement for hierarchical classification task. We further provide a theoretical guarantee bounding the expected task loss of prompts sampled from a DMP.

Poster
Diffusion Fine-Tuning: Iterative Refinement for Advanced Grounding with Diffusion Large Language Models

Zhangyang Qi, Jinsong Li, Jiaqi Wang, Hengshuang Zhao

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While Large Vision-Language Models (LVLMs) excel at bounding-box grounding, they struggle with precise spatial tasks such as polygon grounding. We attribute this bottleneck to two properties of the vertex-level autoregressive (AR) paradigm used by current LVLMs: (1) errors in early-emitted vertices propagate uncorrected through the rest of the sequence, and (2) the model commits to local vertex placement before observing the full contour, leading to suboptimal allocation of a fixed vertex budget. We propose Diffusion Fine-Tuning (DFT), which removes the vertex-level sequential dependency by placing all 2N coordinate tokens under a single discrete-diffusion denoiser, while introducing a much shorter digit-level factorisation: each coordinate is decomposed into hundreds, tens, and units digits, and the reverse process is trained to predict them coarse-to-fine. We train this with a Hierarchical Curriculum Learning strategy that progressively refines loss supervision from macro-contour to per-pixel detail. Under matched fine-tuning protocols, DFT matches strong AR LVLMs on 2D bounding-box grounding and improves over them on 16-point polygon grounding; the same network and training recipe extend to 9-DoF monocular 3D bounding-box grounding under a 9-parameter coordinate parameterisation. A block-wise top-k decoder closes most of the latency gap to AR and recovers most of the quality lost when scaling beyond 16 vertices. We do not claim to eliminate sequential dependence in general: vertex-level O(N) AR decoding is replaced by K joint denoising steps (K=12 in this work), with the three-stage digit hierarchy entering as a training-time loss factorisation rather than an inference-time chain.

Poster
DeepVoting: Learning and Improving Voting Rules with Fine-Tuning

Leonardo Matone, Ben Abramowitz, Ben Armstrong, Avinash Balakrishnan, Nicholas Mattei

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Recently, social choice theory has been found broadly useful for AI alignment and evaluation, often based on the axiomatic properties for combining preferences provided by social choice functions. However, for many sets of axioms, functions which $\textit{never}$ violate the axioms are known to not exist, e.g., Arrow's Impossibility Theorem. Recent work on learning novel rules to $\textit{minimize}$ axiom violations shows the effectiveness of machine learning but explores a limited class of axioms. In this work we show the effectiveness of standard social choice data structures as features for learning existing voting rules, resulting in networks that have better accuracy than past approaches while using an order of magnitude fewer parameters. Subsequently, we develop a process for $\textit{adding axiomatic properties}$ to existing voting rules. By building novel axiomatic loss functions we are able to use transfer learning to fine-tune existing voting rules in a way that quantitatively preserves their original behaviour while also exhibiting strong adherence to previously absent axiomatic properties, resulting in novel voting rules that are $\textit{closer}$ to the impossibility frontier than those in the machine learning or theoretical literature.

Poster
DRIVE: Fine-tuning via Data Contribution- and Diversity-aware Weighting with Prior Regularization

Qing Liu, Xinrui Chen, Weiyao Zhu, Yi Du, Ou Wu

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Single-stage fine-tuning is pervasive, yet catastrophic forgetting persists when the source pre-training data is inaccessible. Data weighting affords a natural lever to modulate sample influence. Yet existing weighting methods lack a principled mechanism to explicitly arbitrate knowledge retention against new-task adaptation, and provide no unified differentiable objective to accommodate auxiliary signals such as sample diversity and sample characteristics. This is because current schemes privilege one goal over the other, and no explicit gradient-compatible encoding exists for such signals. To address this, we propose $\textbf{DRIVE}$, a principled and efficient weight assignment framework. It derives per-sample weights via a unified differentiable objective where three coupled signals co-evolve: Shapley additivity splits contribution into anti-forgetting and adaptation components, which are reshaped by a covariance-based diversity term and stabilized by a sample-characteristic prior. Far from a mere combination, this yields an end-to-end gradient-based scheme balancing stability against plasticity. Theoretically, we prove that DRIVE enjoys superior stability-plasticity guarantees over existing weighting schemes and enhances parameter estimation robustness. Empirically, it attains superior overall performance, faster convergence, and stronger robustness. Code at https://anonymous.4open.science/r/DRIVE-158.

Poster
DEFT: Disentanglement-Enhanced Fine-Tuning for EEG Foundation Models

Yuqiu Deng, Muyun Jiang, Zongpeng Zhang, Mingqing Xiao, Yansen Wang, Peiliang Gong, XINLIANG ZHOU, Yi Ding, Ziyu Jia, Cuntai Guan, Chenyu Liu

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EEG foundation models (EFMs) have improved EEG representation learning by transferring knowledge from large-scale multi-subject pretraining to downstream tasks. However, their pretrained embeddings often retain substantial subject-related variation, placing an additional burden on the downstream classifier, especially in cross-subject settings. To address this issue, we propose DISENTANGLED EFM FINE-TUNING (DEFT), a plug-and-play adapter for EFM fine-tuning. DEFT encourages branch disentanglement of pretrained tokens into task-oriented content and subject-consistent style, then performs downstream prediction from the content branch. It instantiates this factorize-before-classify design with recursive Gaussian refinement, temporal-variance regularization, subject-aware contrastive learning, and reconstruction. Experiments across multiple EEG datasets and four EFM backbones show that DEFT improves matched fine-tuning baselines. Further ablations and analyses support the intended content/style branch organization.

Poster
CrafterDojo: A Suite of Foundation Models for Building Open-Ended Embodied Agents in Crafter

Junyeong Park, Hyeonseo Cho, Sungjin Ahn

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Foundation models are central to building general-purpose embodied agents. Minecraft has become the dominant testbed for this paradigm, but its computational and engineering overhead limits rapid iteration and controlled analysis. Crafter offers a lightweight alternative yet lacks the foundation model ecosystem required for such research. We introduce CrafterDojo, a suite of foundation models, datasets, and data-generation toolkits that establishes Crafter as a testbed for foundation-model-based embodied intelligence, providing CrafterVPT, CrafterCLIP, and CrafterSteve-1. To address Crafter's data scarcity, CrafterDojo includes automatic tools that generate diverse synthetic demonstrations and aligned video-language pairs, yielding the CrafterPlay and CrafterCaption datasets. Experiments show that these datasets support effective foundation model training and enable hierarchical agents that outperform non-hierarchical baselines on long-horizon tasks. We release all code, models, and datasets.

Poster
Compute-Optimal Pretrain--Fine-tune in Ridge Gradient Flow

Alex Buna, Fanghui Liu, Patrick Rebeschini

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Pretraining followed by fine-tuning introduces a compute-allocation problem: under a fixed training budget, time spent improving the upstream objective reduces the time available for downstream adaptation. Despite its practical importance, this trade-off is not yet well understood theoretically, even in simple models. In this paper, we cast compute allocation as a time-split problem under a two-stage pretrain–fine-tune procedure with fixed total optimisation time, using regularised least squares trained by gradient flow as a tractable setting. We characterise the optimal switching time under data-dependent evaluation geometries induced by the fine-tuning problem. Our results show that the allocation depends on how pretraining directions affect fine-tuning predictions and how fine-tuning shifts are seen through downstream data geometry. In particular, the relevant quantities are determined by prediction-relevant spectral components of the pretraining and fine-tuning empirical covariances. Technically, the analysis relies on a basis-invariant, eigenspace-level spectral decomposition, together with perturbative control of the non-commuting pretraining and fine-tuning dynamics.

Poster
Compact SO(3) Equivariant Atomistic Foundation Models via Structural Pruning

Chen Wang, Siyu Hu, Guangming Tan, Weile Jia

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SO(3) equivariant graph neural networks have become the dominant paradigm for atomistic foundation models, achieving high accuracy and data efficiency by building rotational symmetry directly into the architecture. Yet the computational cost of their higher-order tensor operations creates a tough trade-off between model accuracy and inference efficiency. In this paper, we propose a structural pruning method for SO(3) equivariant atomistic foundation models to bridge this accuracy-efficiency gap. The pruning is applied along the channel and order dimensions, with each irreducible representation kept or removed as a complete block, thereby retaining SO(3) equivariance. Starting from a large checkpoint, the pruned model substantially reduces the inference cost while retaining higher accuracy than an independently trained small model. The pruned MACE-MP model outperforms the official from-scratch trained small model on 7 of 9 metrics on the Matbench Discovery leaderboard. In terms of efficiency, compressed MACE-MP and MACE-OFF models contain 1.5$\times$ to 4$\times$ fewer parameters and require 2.5$\times$ to 4$\times$ less pre-training compute than training a small model from scratch. For downstream applications, fine-tuning the pruned model reduces energy and force errors by 70.1\% and 34.4\% compared to training task-specific models from scratch across eight representative downstream datasets. We demonstrate that the method generalizes to other SO(3) equivariant architectures (SevenNet, eSCN) and can be combined with quantization and knowledge distillation for further gains.

Oral
Communication-Efficient Personalized Adaptation via Federated-Local Model Merging

Yinan Zou, Md Kamran Chowdhury Shisher, Christopher Brinton, Vishrant Tripathi

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Parameter-efficient fine-tuning methods, such as LoRA, offer a practical way to adapt large vision and language models to client tasks. However, this becomes particularly challenging under task-level heterogeneity in federated deployments. In this regime, personalization requires balancing general knowledge with personalized knowledge, yet existing approaches largely rely on heuristic mixing rules and lack theoretical justification. Moreover, prior model merging approaches are also computation and communication intensive, making the process inefficient in federated settings. In this work, we propose Potara, a principled framework for federated personalization that constructs a personalized model for each client by merging two complementary models: (i) a federated model capturing general knowledge, and (ii) a local model capturing personalized knowledge. Through the construct of linear mode connectivity, we show that the expected task loss admits a variance trace upper bound, whose minimization yields closed-form optimal mixing weights that guarantee a tighter bound for the merged model than for either the federated or local model alone. Experiments on vision and language benchmarks show that Potara consistently improves personalization while reducing communication, leading to a strong performance-communication trade-off.

Poster
Coarse-to-Fine 3D MRI Reconstruction via Resolution-Agnostic Neural Operators

Jiayun (Peter) Wang, Ruibo Wang, Valentin Duruisseaux, Ram Daftari, Weijie Gan, Armeet Jatyani, Boris Bonev, Animashree Anandkumar

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Deep-learning-based 3D MRI reconstruction is limited in practice by the GPU memory and compute cost of full-volume training. A common workaround is to train at lower resolution and run inference at higher resolution, but standard neural networks are resolution-specific and degrade substantially when evaluated outside the training setting. We instead use resolution-agnostic neural operators (NOs) and propose KIR-NO (k-space-to-Image Reconstruction Neural Operator), a coarse-to-fine, discretization-agnostic framework for accelerated 3D MRI reconstruction. KIR-NO is trained with full backpropagation on memory-feasible low-resolution volumes and applied zero-shot to higher-resolution volumes at inference, without fine-tuning. Its core building block is a 3D local neural operator based on discrete-continuous convolutions: convolutional filters are parameterized in a continuous basis (we propose and empirically compare two 3D bases, piecewise-linear and Morlet-wavelet) and sampled at arbitrary voxel resolutions while preserving the local inductive bias of convolution. KIR-NO integrates these learned operators with physics-based consistency: a k-space neural-operator head first refines the undersampled Fourier measurements, and image-space neural-operator cascades then refine the reconstruction through interleaved data-consistency updates. Across 3D knee (SKM-TEA) and brain (BraTS 2021) MRI benchmarks, KIR-NO consistently outperforms classical and CNN baselines: it improves over a state-of-the-art 3D CNN by 4.13 dB PSNR at half resolution under 4× acceleration on SKM-TEA, with gains persisting at 8× and 16×, and exceeds the same baseline by 13.63 dB under zero-shot full-resolution transfer on BraTS. Together, these results show that KIR-NO enables scalable, memory-efficient, and resolution-flexible 3D MRI reconstruction across anatomies.

Poster
ChildPose: Foundation for Children Pose Modeling

Jiakai Chen, Yifan Shen, Boyi Li, Chuanmiao Dong, Xu Cao

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Human pose estimation has advanced rapidly driven by large-scale adult-centric models. However, children remain significantly underrepresented due to data scarcity, distinct body morphology, and unique motion dynamics. We introduce ChildPose, a modular video foundation model designed for child-centric pose estimation. ChildPose transforms pretrained pose encoders into a streaming pediatric model via memory-augmented temporal attention and age-aware co-training. By maintaining a memory bank of adjacent frame representations, the model achieves robust localization under motion blur, occlusion, and atypical poses, while an auxiliary age-prediction objective enforces representations that capture developmental morphology. We curate a diverse, video-based pediatric dataset spanning various age groups and capture conditions, evaluating out-of-distribution generalizability on entirely unseen subjects. Across multiple 2D baselines, ChildPose consistently outperforms both off-the-shelf models and child-data fine-tuned variants, while ensuring stable sequence-level predictions. Our results underscore that effective pediatric pose estimation necessitates child-specific modeling beyond standard adult-centric estimators.

Poster
Certification-Enhanced Generalization Bounds

Leo Elmecker-Plakolm, Matthew R Wicker

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We investigate the use of formal methods to provide tight and sound generalization bounds for learning algorithms. By casting the traditional notion of algorithmic stability as a specification to be verified, we demonstrate that recent advances in reachability analysis can yield provable bounds on the generalization of a given model and algorithm on a sample dataset. As sample-specific algorithmic stability is insufficient to bound the usual distributional notion of generalization, we develop a novel concentration inequality to connect the sample-specific results of formal certification algorithms to the required distributional analysis.The resulting framework enables the theoretical analysis of prior generalization bounds to extend far beyond their original restrictive analytical assumptions while achieving a provably sound bound on the generalization gap. In practice, we demonstrate that our framework provide formal generalization guarantees that are orders of magnitude tighter than alternative computational approaches at scales ranging from toy datasets to fine-tuning of modern large language models. While we implement certification-enhanced versions of several well-known stability results, future extensions of our approach will enable tighter bounds and enhanced practical adoption across the spectrum of modern generalization bounds.

Poster
CanViT: Toward Active-Vision Foundation Models

Yohaï-Eliel BERREBY, Sabrina Du, Audrey Durand, B. S Krishna

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Active computer vision promises efficient, biologically plausible perception through sequential, localized glimpses, but lacks scalable general-purpose architectures and pretraining pipelines, leaving Active-Vision Foundation Models (AVFMs) underexplored. We introduce CanViT, the first task- and policy-agnostic AVFM. CanViT uses scene-relative RoPE to bind a retinotopic Vision Transformer backbone and a spatiotopic scene-wide latent workspace, the canvas. Efficient interaction with this high-capacity working memory is supported by Canvas Attention, a novel asymmetric cross-attention mechanism. We decouple thinking (backbone-level) and memory (canvas-level), eliminating canvas-side self-attention and fully-connected layers to achieve fast sequential inference and scalability to high output resolutions. We propose a label-free active vision pretraining scheme, policy-agnostic passive-to-active dense latent distillation: reconstructing scene-wide DINOv3 embeddings from sequences of low-resolution glimpses with randomized locations, zoom levels, and lengths. We pretrain CanViT-B from a random initialization on 13.2 million ImageNet-21k scenes--an order of magnitude more than previous active models--and 1 billion random glimpses, in 166 hours on a single H100. On ADE20K segmentation, a frozen CanViT-B achieves 38.5% mIoU in a single low-resolution glimpse, outperforming the best active model's 27.6% with 20x fewer inference FLOPs as well as its FLOP- or input-matched DINOv3 teacher. Given additional glimpses, CanViT-B reaches 45.9% ADE20K mIoU. On ImageNet-1k classification, CanViT-B also sets a new active-vision state of the art, with 84.5% top-1 accuracy after fine-tuning. CanViT generalizes to longer rollouts, larger scenes, and new policies. Our work narrows the wide gap between passive and active computer vision, demonstrating the potential of task- and policy-agnostic AVFM pretraining.

Poster
Calibrating Scientific Foundation Models with Inference-Time Stochastic Attention

Akash Yadav, Taiwo Adebiyi, Ruda Zhang

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Transformer-based scientific foundation models are increasingly deployed in high-stakes settings, but current architectures give deterministic outputs and provide limited support for calibrated predictive uncertainty. We propose Stochastic Attention, a sample average lightweight inference-time modification that randomizes attention by replacing softmax weights with normalized multinomial samples controlled by a single concentration parameter, and produces predictive ensembles without retraining. To set this parameter, we introduce a calibration objective that matches the stochastic attention output with the target, yielding an efficient univariate post-hoc tuning problem. We evaluate this mechanism on scientific foundation models for weather and time-series forecasting, as well as several regression tasks. Across benchmarks against uncertainty-aware baselines, we find that Sample Average Stochastic Attention achieves the strongest native calibration and the sharpest prediction intervals at comparable calibration, with adaptation costs nearly three orders of magnitude lower than the next-best baseline.

Poster
CORTEG: Foundation Models Enable Cross-Modality Representation Transfer from Scalp to Intracranial Brain Recordings

Liuyin Yang, Qiang Sun, Bob Van Dyck, Eva C Merino, Marc M Van Hulle

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Intracranial electrocorticography (ECoG) offers high–signal-to-noise access to cortical activity for brain–computer interfaces, yet limited per-patient data has led most prior work to rely on small, subject-specific decoders that neglect information shared across patients. We investigate whether large pretrained scalp-EEG foundation models (EEG FMs) can be adapted to ECoG, enabling cross-patient learning and competitive decoding performance while calibrating to a held-out patient in $10$--$30$ minutes on a single GPU. We introduce CORTEG, a cross-modality transfer framework that combines a pretrained EEG FM backbone, an electrode-aware KNNSoftFourier spatial adapter, a dual-stream tokenizer for low-frequency and high-gamma activity, and a leave-one-subject-out fine-tuning strategy. We evaluate CORTEG on two challenging regression tasks: public finger trajectory regression (n=9) and private audio envelope regression (n=16). CORTEG matches or exceeds the strongest task-specific baselines on both tasks: it reaches the highest mean correlation among compared methods on the public finger benchmark (gain not statistically significant on $n{=}9$ subjects), with larger and statistically significant gains on the audio task and in low-data per-patient calibration. Feature analyses align with neurophysiology, and latent manifolds capture low-dimensional finger-movement structure. CORTEG provides systematic evidence that scalp-EEG pretraining can be repurposed for ECoG decoding, enabling data-efficient intracranial BCIs that can adapt to new patients.

Poster
CORA: Per-Slice Coherent Orthogonal Rotation for SVD-based Low-Rank Adaptation

Pengcheng Wang, Ziran Liu, Wei Wang, Wei Jiang

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Parameter-Efficient Fine-Tuning (PEFT) commonly adapts pretrained weights through low-rank updates, and recent methods further exploit the singular value decomposition (SVD) of the base weight for initialization or subspace selection. However, these methods do not explicitly preserve the coupled geometry between the pretrained left and right singular bases. Motivated by recent minimum-perturbation theory, which shows that stable finetuning admits a coherent SVD rotation in which a single orthogonal $Q$ acts on both the left singular basis $U_0$ and the right singular basis $V_0$, we prove a per-slice analogue: each row slice of $W_0$ can be adapted by a shared orthogonal rotation $Q_i$ on its left basis $U_i$ and right basis $V_i$ together with a diagonal spectrum shift. We instantiate this form as **CORA** (*Coherent Orthogonal Rotation Adaptation*), which applies per-slice orthogonal rotations and a per-layer diagonal scale to the rank-$r$ SVD truncation of $W_0$. CORA uses $\tfrac{1}{2}m(r{-}1)$ trainable parameters per linear layer, about $4{\times}$ fewer than LoRA at the same rank. CORA outperforms LoRA, DoRA, PiSSA, and MiLoRA on commonsense reasoning and code generation while using $\sim 8{\times}$ fewer parameters.

Poster
CLEF: EEG Foundation Models for Learning Clinical Semantics

Peng Cao, Ali Mirzazadeh, Jong W Lee, Aleksandar Videnovic, Dina Katabi

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Clinical EEG interpretation requires reasoning over full EEG sessions and integrating signal patterns with clinical context. Existing EEG foundation models are largely designed for short-window decoding and do not incorporate clinical context. We introduce CLEF, a clinically grounded long-context EEG foundation model. CLEF represents EEG sessions as 3D multitaper spectrogram tokens, enabling tractable Transformer modeling at session scale, and aligns embeddings with neurologist reports and structured EHR data through contrastive objectives. We evaluate CLEF on a new 234-task benchmark spanning disease phenotypes, medication exposures, and EEG findings, with more than 260k EEG sessions from over 108k patients. CLEF outperforms prior EEG foundation models on 229 of 234 tasks, improving mean AUROC from 0.65 to 0.74. Reconstruction-only pretraining surpasses prior EEG foundation models, while report and EHR alignment yields further gains. Held-out concept and external-cohort experiments suggest that these representations transfer beyond observed alignment targets. These results support session-scale, clinically grounded representation learning as a promising foundation-model paradigm for clinical EEG.

Poster
C2FT: Enhancing Fine-Grained Perception in MLLMs via Confuse-then-Contrast Fine-Tuning

Shaoxuan He, Benlei Cui, Shikai Qiu, Yuwen Zhai, Hui Xue&#x27, Longtao Huang, Jingqun Tang, Haiwen Hong

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Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities, yet they frequently struggle with fine-grained visual perception, often suffering from hallucinations when faced with visually similar but semantically distinct instances. A major underlying cause is the conventional single-sample Supervised Fine-Tuning (SFT) paradigm, which isolates training instances and limits the model's ability to explicitly learn subtle discriminative boundaries. To address this, we propose **C2FT**, a novel **Confuse-then-Contrast Fine-Tuning** framework that enhances fine-grained perception by shifting from independent supervision to joint supervision. Specifically, C2FT assesses the MLLM's internal uncertainty to dynamically mine model-specific semantic confusions, subsequently constructing challenging multi-image groups comprising hard positive and hard negative samples. By interleaving these samples into a unified prompt, our approach forces the MLLM's internal attention mechanisms to cross-reference images and explicitly capture localized visual discrepancies. Extensive experiments on both Fine-Grained Visual Classification (FGVC) and visual question answering (VQA) benchmarks demonstrate the effectiveness of C2FT. For instance, on the Qwen3-VL-4B model, our approach achieves an average improvements of 3.87\% and 4.35\% points over standard SFT and GRPO baselines, respectively.

Poster
Beyond ViT Tokens: Masked-Diffusion Pretrained Convolutional Pathology Foundation Model for Cell-Level Dense Prediction

Weiming Chen, Xitong Ling, Zhenyang Cai, Xidong Wang, Jiawen Li, Tian Guan, Benyou Wang, Yonghong He

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Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely on patch tokenization, which can disrupt spatial continuity and weaken local morphological details needed for cell-level prediction. To address this, we propose Masked-Diffusion Convolutional Foundation Models, termed ConvNeXt Masked-Diffusion (CMD), a self-supervised convolutional generative pretraining framework for dense pathology representation learning. CMD uses a fully convolutional ConvNeXt-UNet backbone, performs masked-diffusion pretraining in pixel space, and incorporates frozen pathology foundation model features through adaptive normalization. Experimental results demonstrate that CMD consistently outperforms existing ViT-based pathology foundation models and even surpasses state-of-the-art end-to-end segmentation methods while fine-tuning only a small number of task-specific parameters across multiple pathology dense prediction tasks. The advantage is particularly pronounced under limited annotation settings, where CMD exhibits stronger robustness and generalization ability. Our findings suggest that purely convolutional architectures can also serve as competitive pathology foundation models for cell-level dense prediction, achieving leading performance within the current ViT-dominated paradigm and providing a scalable, high-performance solution that better preserves histological structural priors for fine-grained pathology understanding. Project page: https://anonymous.4open.science/r/ConvNeXt-Masked-Diffusion-5BC6.

Poster
Beyond LoRA vs. Full Fine-Tuning: Gradient-Guided Optimizer Routing for LLM Adaptation

Haozhan Tang, Xiuqi Zhu, Xinyin Zhang, Boxun Li, Virginia Smith, Kevin Kuo

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Recent literature on fine-tuning Large Language Models highlights a fundamental debate. While Full Fine-Tuning (FFT) provides the representational plasticity required for high-entropy knowledge injection, Low-Rank Adaptation (LoRA) can match or surpass FFT performance because many tasks only require updates in a low-rank space and benefit from LoRA's additional regularization. Through empirical evaluation across diverse tasks (SQL, Medical QA, and Counterfactual Knowledge) and varying language models (Gemma-3-1B, Qwen2.5-1.5B, and Qwen2.5-3B), we verify both trends and demonstrate that relying solely on either static architecture is structurally limited. To address this challenge, we propose a Mixture of LoRA and Full (MoLF) Fine-Tuning, a unified framework that enables continuous navigation between both training regimes. MoLF dynamically routes updates between FFT and LoRA at the optimizer level to ensure that exact gradient signals are available to both experts throughout training, yielding stable training dynamics. For memory-constrained environments, we also introduce MoLF-Efficient, which freezes base weights and only routes updates among a pair of LoRA experts of potentially varying rank. Our evaluations show that MoLF either improves on or stays within $1.5$% of the better of FFT and LoRA across all settings, while MoLF-Efficient outperforms prior adaptive LoRA approaches by up to $20$% on Fact and $9$% on Med and SQL.

Poster