NeurIPS 2024 Papers

Conference on Neural Information Processing Systems

Decision breakdown

4,562papers

Counted from the official paper list; may differ slightly from the number the conference announced.

  • Oral
    721.6%
  • Spotlight
    3828.4%
  • Poster
    4,06489.1%
  • Other / unlabeled
    441.0%

Browse all papers

Topic: Image Generation · 318 papers · Reset filters

Identifying and Solving Conditional Image Leakage in Image-to-Video Diffusion Model

Min Zhao, Hongzhou Zhu, Chendong Xiang, Kaiwen Zheng, Chongxuan Li, Jun Zhu

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Diffusion models have obtained substantial progress in image-to-video generation. However, in this paper, we find that these models tend to generate videos with less motion than expected. We attribute this to the issue called conditional image leakage, where the image-to-video diffusion models (I2V-DMs) tend to over-rely on the conditional image at large time steps. We further address this challenge from both inference and training aspects. First, we propose to start the generation process from an earlier time step to avoid the unreliable large-time steps of I2V-DMs, as well as an initial noise distribution with optimal analytic expressions (Analytic-Init) by minimizing the KL divergence between it and the actual marginal distribution to bridge the training-inference gap. Second, we design a time-dependent noise distribution (TimeNoise) for the conditional image during training, applying higher noise levels at larger time steps to disrupt it and reduce the model's dependency on it. We validate these general strategies on various I2V-DMs on our collected open-domain image benchmark and the UCF101 dataset. Extensive results show that our methods outperform baselines by producing higher motion scores with lower errors while maintaining image alignment and temporal consistency, thereby yielding superior overall performance and enabling more accurate motion control. The project page: \url{https://cond-image-leak.github.io/}.

Poster
ActAnywhere: Subject-Aware Video Background Generation

Boxiao Pan, Zhan Xu, Chun-Hao Paul Huang, Krishna Kumar Singh, Yang Zhou, Leonidas Guibas, Jimei Yang

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We study a novel problem to automatically generate video background that tailors to foreground subject motion. It is an important problem for the movie industry and visual effects community, which traditionally requires tedious manual efforts to solve. To this end, we propose ActAnywhere, a video diffusion model that takes as input a sequence of foreground subject segmentation and an image of a novel background and generates a video of the subject interacting in this background. We train our model on a large-scale dataset of 2.4M videos of human-scene interactions. Through extensive evaluation, we show that our model produces videos with realistic foreground-background interaction while strictly following the guidance of the condition image. Our model generalizes to diverse scenarios including non-human subjects, gaming and animation clips, as well as videos with multiple moving subjects. Both quantitative and qualitative comparisons demonstrate that our model significantly outperforms existing methods, which fail to accomplish the studied task. Please visit our project webpage at https://actanywhere.github.io.

Poster
Enhancing Motion in Text-to-Video Generation with Decomposed Encoding and Conditioning

Penghui Ruan, Pichao WANG, Divya Saxena, Jiannong Cao, Yuhui Shi

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Despite advancements in Text-to-Video (T2V) generation, producing videos with realistic motion remains challenging. Current models often yield static or minimally dynamic outputs, failing to capture complex motions described by text. This issue stems from the internal biases in text encoding which overlooks motions, and inadequate conditioning mechanisms in T2V generation models. To address this, we propose a novel framework called DEcomposed MOtion (DEMO), which enhances motion synthesis in T2V generation by decomposing both text encoding and conditioning into content and motion components. Our method includes a content encoder for static elements and a motion encoder for temporal dynamics, alongside separate content and motion conditioning mechanisms. Crucially, we introduce text-motion and video-motion supervision to improve the model's understanding and generation of motion. Evaluations on benchmarks such as MSR-VTT, UCF-101, WebVid-10M, EvalCrafter, and VBench demonstrate DEMO's superior ability to produce videos with enhanced motion dynamics while maintaining high visual quality. Our approach significantly advances T2V generation by integrating comprehensive motion understanding directly from textual descriptions. Project page: https://PR-Ryan.github.io/DEMO-project/

Poster
HardCore Generation: Generating Hard UNSAT Problems for Data Augmentation

Joseph Cotnareanu, Zhanguang Zhang, Hui-Ling Zhen, Yingxue Zhang, Mark Coates

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Efficiently determining the satisfiability of a boolean equation --- known as the SAT problem for brevity --- is crucial in various industrial problems. Recently, the advent of deep learning methods has introduced significant potential for enhancing SAT solving. However, a major barrier to the advancement of this field has been the scarcity of large, realistic datasets. The majority of current public datasets are either randomly generated or extremely limited, containing only a few examples from unrelated problem families. These datasets are inadequate for meaningful training of deep learning methods. In light of this, researchers have started exploring generative techniques to create data that more accurately reflect SAT problems encountered in practical situations. These methods have so far suffered from either the inability to produce challenging SAT problems or time-scalability obstacles. In this paper we address both by identifying and manipulating the key contributors to a problem's ``hardness'', known as cores. Although some previous work has addressed cores, the time costs are unacceptably high due to the expense of traditional heuristic core detection techniques. We introduce a fast core detection procedure that uses a graph neural network. Our empirical results demonstrate that we can efficiently generate problems that remain hard to solve and retain key attributes of the original example problems. We show via experiment that the generated synthetic SAT problems can be used in a data augmentation setting to provide improved prediction of solver runtimes.

Poster
Phased Consistency Models

Fu-Yun Wang, Zhaoyang Huang, Alexander William Bergman, Dazhong Shen, Peng Gao, Michael Lingelbach, Keqiang Sun, Weikang BIAN, Guanglu Song, Yu Liu, Xiaogang Wang, Hongsheng Li

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Consistency Models (CMs) have made significant progress in accelerating the generation of diffusion models. However, their application to high-resolution, text-conditioned image generation in the latent space remains unsatisfactory. In this paper, we identify three key flaws in the current design of Latent Consistency Models~(LCMs). We investigate the reasons behind these limitations and propose Phased Consistency Models (PCMs), which generalize the design space and address the identified limitations. Our evaluations demonstrate that PCMs outperform LCMs across 1--16 step generation settings. While PCMs are specifically designed for multi-step refinement, they achieve comparable 1-step generation results to previously state-of-the-art specifically designed 1-step methods. Furthermore, we show the methodology of PCMs is versatile and applicable to video generation, enabling us to train the state-of-the-art few-step text-to-video generator. Our code is available at https://github.com/G-U-N/Phased-Consistency-Model.

Poster
HEST-1k: A Dataset For Spatial Transcriptomics and Histology Image Analysis

Guillaume Jaume, Paul Doucet, Andrew H. Song, Ming Y. Lu, Cristina Almagro Pérez, Sophia J Wagner, Anurag Jayant Vaidya, Richard J. Chen, Drew FK Williamson, Ahrong Kim, Faisal Mahmood

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Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and lack of standards have constrained computational methods in ST to narrow tasks and small cohorts. In addition, the underlying tissue morphology, as reflected by H&E-stained whole slide images (WSIs), encodes rich information often overlooked in ST studies. Here, we introduce HEST-1k, a collection of 1,229 spatial transcriptomic profiles, each linked to a WSI and extensive metadata. HEST-1k was assembled from 153 public and internal cohorts encompassing 26 organs, two species (Homo Sapiens and Mus Musculus), and 367 cancer samples from 25 cancer types. HEST-1k processing enabled the identification of 2.1 million expression-morphology pairs and over 76 million nuclei. To support its development, we additionally introduce the HEST-Library, a Python package designed to perform a range of actions with HEST samples. We test HEST-1k and Library on three use cases: (1) benchmarking foundation models for pathology (HEST-Benchmark), (2) biomarker exploration, and (3) multimodal representation learning. HEST-1k, HEST-Library, and HEST-Benchmark can be freely accessed at https://github.com/mahmoodlab/hest.

Spotlight
Adaptive Image Quality Assessment via Teaching Large Multimodal Model to Compare

Hanwei Zhu, Haoning Wu, Yixuan Li, Zicheng Zhang, Baoliang Chen, Lingyu Zhu, Yuming Fang, Guangtao Zhai, Weisi Lin, Shiqi Wang

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While recent advancements in large multimodal models (LMMs) have significantly improved their abilities in image quality assessment (IQA) relying on absolute quality rating, how to transfer reliable relative quality comparison outputs to continuous perceptual quality scores remains largely unexplored. To address this gap, we introduce an all-around LMM-based NR-IQA model, which is capable of producing qualitatively comparative responses and effectively translating these discrete comparison outcomes into a continuous quality score. Specifically, during training, we present to generate scaled-up comparative instructions by comparing images from the same IQA dataset, allowing for more flexible integration of diverse IQA datasets. Utilizing the established large-scale training corpus, we develop a human-like visual quality comparator. During inference, moving beyond binary choices, we propose a soft comparison method that calculates the likelihood of the test image being preferred over multiple predefined anchor images. The quality score is further optimized by maximum a posteriori estimation with the resulting probability matrix. Extensive experiments on nine IQA datasets validate that the Compare2Score effectively bridges text-defined comparative levels during training with converted single image quality scores for inference, surpassing state-of-the-art IQA models across diverse scenarios. Moreover, we verify that the probability-matrix-based inference conversion not only improves the rating accuracy of Compare2Score but also zero-shot general-purpose LMMs, suggesting its intrinsic effectiveness.

Spotlight
EvoCodeBench: An Evolving Code Generation Benchmark with Domain-Specific Evaluations

Jia Li, Ge Li, Xuanming Zhang, Yunfei Zhao, Yihong Dong, Zhi Jin, Binhua Li, Fei Huang, Yongbin Li

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How to evaluate Large Language Models (LLMs) in code generation remains an open question. Many benchmarks have been proposed, but they have two limitations, i.e., data leakage and lack of domain-specific evaluation. The former hurts the fairness of benchmarks, and the latter hinders practitioners from selecting superior LLMs for specific programming domains. To address these two limitations, we propose a new benchmark - EvoCodeBench, which has the following advances: (1) Evolving data. EvoCodeBench will be dynamically updated every period (e.g., 6 months) to avoid data leakage. This paper releases the first version - EvoCodeBench-2403, containing 275 samples from 25 repositories. (2) A domain taxonomy and domain labels. Based on the statistics of open-source communities, we design a programming domain taxonomy consisting of 10 popular domains. Based on the taxonomy, we annotate each sample in EvoCodeBench with a domain label. EvoCodeBench provides a broad platform for domain-specific evaluations. (3) Domain-specific evaluations. Besides the Pass@k, we compute the Domain-Specific Improvement (DSI) and define LLMs' comfort and strange domains. These evaluations help practitioners select superior LLMs in specific domains and discover the shortcomings of existing LLMs. Besides, EvoCodeBench is collected by a rigorous pipeline and aligns with real-world repositories in multiple aspects (e.g., code distributions). We evaluate 8 popular LLMs (e.g., gpt-4, DeepSeek Coder, StarCoder 2) on EvoCodeBench and summarize some insights. EvoCodeBench reveals the actual abilities of these LLMs in real-world repositories. For example, the highest Pass@1 of gpt-4 on EvoCodeBench-2403 is only 20.74%. Besides, we evaluate LLMs in different domains and discover their comfort and strange domains. For example, gpt-4 performs best in most domains but falls behind others in the Internet domain. StarCoder 2-15B unexpectedly performs well in the Database domain and even outperforms 33B LLMs. We release EvoCodeBench, all prompts, and LLMs' completions for further community analysis.

Poster
Data Attribution for Text-to-Image Models by Unlearning Synthesized Images

Sheng-Yu Wang, Aaron Hertzmann, Alexei A. Efros, Jun-Yan Zhu, Richard Zhang

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The goal of data attribution for text-to-image models is to identify the training images that most influence the generation of a new image. Influence is defined such that, for a given output, if a model is retrained from scratch without the most influential images, the model would fail to reproduce the same output. Unfortunately, directly searching for these influential images is computationally infeasible, since it would require repeatedly retraining models from scratch. In our work, we propose an efficient data attribution method by simulating unlearning the synthesized image. We achieve this by increasing the training loss on the output image, without catastrophic forgetting of other, unrelated concepts. We then identify training images with significant loss deviations after the unlearning process and label these as influential. We evaluate our method with a computationally intensive but "gold-standard" retraining from scratch and demonstrate our method's advantages over previous methods.

Poster
ODGEN: Domain-specific Object Detection Data Generation with Diffusion Models

JingYuan Zhu, Shiyu Li, Yuxuan Liu, Jian Yuan, Ping Huang, Jiulong Shan, Huimin Ma

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Modern diffusion-based image generative models have made significant progress and become promising to enrich training data for the object detection task. However, the generation quality and the controllability for complex scenes containing multi-class objects and dense objects with occlusions remain limited. This paper presents ODGEN, a novel method to generate high-quality images conditioned on bounding boxes, thereby facilitating data synthesis for object detection. Given a domain-specific object detection dataset, we first fine-tune a pre-trained diffusion model on both cropped foreground objects and entire images to fit target distributions. Then we propose to control the diffusion model using synthesized visual prompts with spatial constraints and object-wise textual descriptions. ODGEN exhibits robustness in handling complex scenes and specific domains. Further, we design a dataset synthesis pipeline to evaluate ODGEN on 7 domain-specific benchmarks to demonstrate its effectiveness. Adding training data generated by ODGEN improves up to 25.3% mAP@.50:.95 with object detectors like YOLOv5 and YOLOv7, outperforming prior controllable generative methods. In addition, we design an evaluation protocol based on COCO-2014 to validate ODGEN in general domains and observe an advantage up to 5.6% in mAP@.50:.95 against existing methods.

Poster
Image Textualization: An Automatic Framework for Generating Rich and Detailed Image Descriptions

Renjie Pi, Jianshu Zhang, Jipeng Zhang, Rui Pan, Zhekai Chen, Tong Zhang

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Image description datasets play a crucial role in the advancement of various applications such as image understanding, text-to-image generation, and text-image retrieval. Currently, image description datasets primarily originate from two sources. One source is the scraping of image-text pairs from the web. Despite their abundance, these descriptions are often of low quality and noisy. Another way is through human labeling. Datasets such as COCO are generally very short and lack details. Although detailed image descriptions can be annotated by humans, the high cost limits their quantity and feasibility. These limitations underscore the need for more efficient and scalable methods to generate accurate and detailed image descriptions. In this paper, we propose an innovative framework termed Image Textualization, which automatically produces high-quality image descriptions by leveraging existing mult-modal large language models (MLLMs) and multiple vision expert models in a collaborative manner. We conduct various experiments to validate the high quality of the descriptions constructed by our framework. Furthermore, we show that MLLMs fine-tuned on our dataset acquire an unprecedented capability of generating richer image descriptions, substantially increasing the length and detail of their output with even less hallucinations.

Poster
Physically Compatible 3D Object Modeling from a Single Image

Minghao Guo, Bohan Wang, Pingchuan Ma, Tianyuan Zhang, Crystal Elaine Owens, Chuang Gan, Joshua B. Tenenbaum, Kaiming He, Wojciech Matusik

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We present a computational framework that transforms single images into 3D physical objects. The visual geometry of a physical object in an image is determined by three orthogonal attributes: mechanical properties, external forces, and rest-shape geometry. Existing single-view 3D reconstruction methods often overlook this underlying composition, presuming rigidity or neglecting external forces. Consequently, the reconstructed objects fail to withstand real-world physical forces, resulting in instability or undesirable deformation -- diverging from their intended designs as depicted in the image. Our optimization framework addresses this by embedding physical compatibility into the reconstruction process. We explicitly decompose the three physical attributes and link them through static equilibrium, which serves as a hard constraint, ensuring that the optimized physical shapes exhibit desired physical behaviors. Evaluations on a dataset collected from Objaverse demonstrate that our framework consistently enhances the physical realism of 3D models over existing methods. The utility of our framework extends to practical applications in dynamic simulations and 3D printing, where adherence to physical compatibility is paramount.

Spotlight
DRIP: Unleashing Diffusion Priors for Joint Foreground and Alpha Prediction in Image Matting

Xiaodi Li, Zongxin Yang, Ruijie Quan, Yi Yang

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Recovering the foreground color and opacity/alpha matte from a single image (i.e., image matting) is a challenging and ill-posed problem where data priors play a critical role in achieving precise results. Traditional methods generally predict the alpha matte and then extract the foreground through post-processing, often failing to produce high-fidelity foreground color. This failure stems from the models' difficulty in learning robust color predictions from limited matting datasets. To address this, we explore the potential of leveraging vision priors embedded in pre-trained latent diffusion models (LDM) for estimating foreground RGBA values in challenging scenarios and rare objects. We introduce Drip, a novel approach for image matting that harnesses the rich prior knowledge of LDM models. Our method incorporates a switcher and a cross-domain attention mechanism to extend the original LDM for joint prediction of the foreground color and opacity. This setup facilitates mutual information exchange and ensures high consistency across both modalities. To mitigate the inherent reconstruction errors of the LDM's VAE decoder, we propose a latent transparency decoder to align the RGBA prediction with the input image, thereby reducing discrepancies. Comprehensive experimental results demonstrate that our approach achieves state-of-the-art performance in foreground and alpha predictions and shows remarkable generalizability across various benchmarks.

Poster
INQUIRE: A Natural World Text-to-Image Retrieval Benchmark

Edward Vendrow, Omiros Pantazis, Alexander Shepard, Gabriel Brostow, Kate E. Jones, Oisin Mac Aodha, Sara Beery, Grant Van Horn

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We introduce INQUIRE, a text-to-image retrieval benchmark designed to challenge multimodal vision-language models on expert-level queries. INQUIRE includes iNaturalist 2024 (iNat24), a new dataset of five million natural world images, along with 250 expert-level retrieval queries. These queries are paired with all relevant images comprehensively labeled within iNat24, comprising 33,000 total matches. Queries span categories such as species identification, context, behavior, and appearance, emphasizing tasks that require nuanced image understanding and domain expertise. Our benchmark evaluates two core retrieval tasks: (1) INQUIRE-Fullrank, a full dataset ranking task, and (2) INQUIRE-Rerank, a reranking task for refining top-100 retrievals. Detailed evaluation of a range of recent multimodal models demonstrates that INQUIRE poses a significant challenge, with the best models failing to achieve an mAP@50 above 50%. In addition, we show that reranking with more powerful multimodal models can enhance retrieval performance, yet there remains a significant margin for improvement. By focusing on scientifically-motivated ecological challenges, INQUIRE aims to bridge the gap between AI capabilities and the needs of real-world scientific inquiry, encouraging the development of retrieval systems that can assist with accelerating ecological and biodiversity research.

Poster
High-Resolution Image Harmonization with Adaptive-Interval Color Transformation

Quanling Meng, Qinglin Liu, Zonglin Li, Xiangyuan Lan, Shengping Zhang, Liqiang Nie

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Existing high-resolution image harmonization methods typically rely on global color adjustments or the upsampling of parameter maps. However, these methods ignore local variations, leading to inharmonious appearances. To address this problem, we propose an Adaptive-Interval Color Transformation method (AICT), which predicts pixel-wise color transformations and adaptively adjusts the sampling interval to model local non-linearities of the color transformation at high resolution. Specifically, a parameter network is first designed to generate multiple position-dependent 3-dimensional lookup tables (3D LUTs), which use the color and position of each pixel to perform pixel-wise color transformations. Then, to enhance local variations adaptively, we separate a color transform into a cascade of sub-transformations using two 3D LUTs to achieve the non-uniform sampling intervals of the color transform. Finally, a global consistent weight learning method is proposed to predict an image-level weight for each color transform, utilizing global information to enhance the overall harmony. Extensive experiments demonstrate that our AICT achieves state-of-the-art performance with a lightweight architecture. The code is available at https://github.com/aipixel/AICT.

Poster
Autoregressive Image Diffusion: Generation of Image Sequence and Application in MRI

Guanxiong Luo, Shoujin Huang, Martin Uecker

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Magnetic resonance imaging (MRI) is a widely used non-invasive imaging modality. However, a persistent challenge lies in balancing image quality with imaging speed. This trade-off is primarily constrained by k-space measurements, which traverse specific trajectories in the spatial Fourier domain (k-space). These measurements are often undersampled to shorten acquisition times, resulting in image artifacts and compromised quality. Generative models learn image distributions and can be used to reconstruct high-quality images from undersampled k-space data. In this work, we present the autoregressive image diffusion (AID) model for image sequences and use it to sample the posterior for accelerated MRI reconstruction. The algorithm incorporates both undersampled k-space and pre-existing information. Models trained with fastMRI dataset are evaluated comprehensively. The results show that the AID model can robustly generate sequentially coherent image sequences. In MRI applications, the AID can outperform the standard diffusion model and reduce hallucinations, due to the learned inter-image dependencies. The project code is available at https://github.com/mrirecon/aid.

Poster
Query-Based Adversarial Prompt Generation

Jonathan Hayase, Ema Borevković, Nicholas Carlini, Florian Tramèr, Milad Nasr

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Recent work has shown it is possible to construct adversarial examples that cause aligned language models to emit harmful strings or perform harmful behavior. Existing attacks work either in the white-box setting (with full access to the model weights), or through _transferability_: the phenomenon that adversarial examples crafted on one model often remain effective on other models. We improve on prior work with a _query-based_ attack that leverages API access to a remote language model to construct adversarial examples that cause the model to emit harmful strings with (much) higher probability than with transfer-only attacks. We validate our attack on GPT-3.5 and OpenAI's safety classifier; we can cause GPT-3.5 to emit harmful strings that current transfer attacks fail at, and we can evade the OpenAI and Llama Guard safety classifiers with nearly 100% probability.

Poster
Generalizable Person Re-identification via Balancing Alignment and Uniformity

Yoonki Cho, Jaeyoon Kim, Woo Jae Kim, Junsik Jung, Sung-eui Yoon

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Domain generalizable person re-identification (DG re-ID) aims to learn discriminative representations that are robust to distributional shifts. While data augmentation is a straightforward solution to improve generalization, certain augmentations exhibit a polarized effect in this task, enhancing in-distribution performance while deteriorating out-of-distribution performance. In this paper, we investigate this phenomenon and reveal that it leads to sparse representation spaces with reduced uniformity. To address this issue, we propose a novel framework, Balancing Alignment and Uniformity (BAU), which effectively mitigates this effect by maintaining a balance between alignment and uniformity. Specifically, BAU incorporates alignment and uniformity losses applied to both original and augmented images and integrates a weighting strategy to assess the reliability of augmented samples, further improving the alignment loss. Additionally, we introduce a domain-specific uniformity loss that promotes uniformity within each source domain, thereby enhancing the learning of domain-invariant features. Extensive experimental results demonstrate that BAU effectively exploits the advantages of data augmentation, which previous studies could not fully utilize, and achieves state-of-the-art performance without requiring complex training procedures. The code is available at https://github.com/yoonkicho/BAU.

Poster
COSMIC: Compress Satellite Image Efficiently via Diffusion Compensation

Ziyuan Zhang, Han Qiu, Zhang Maosen, Jun Liu, Bin CHEN, Tianwei Zhang, Hewu Li

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With the rapidly increasing number of satellites in space and their enhanced capabilities, the amount of earth observation images collected by satellites is exceeding the transmission limits of satellite-to-ground links. Although existing learned image compression solutions achieve remarkable performance by using a sophisticated encoder to extract fruitful features as compression and using a decoder to reconstruct. It is still hard to directly deploy those complex encoders on current satellites' embedded GPUs with limited computing capability and power supply to compress images in orbit. In this paper, we propose COSMIC, a simple yet effective learned compression solution to transmit satellite images. We first design a lightweight encoder (i.e. reducing FLOPs by 2.5~5X) on satellite to achieve a high image compression ratio to save satellite-to-ground links. Then, for reconstructions on the ground, to deal with the feature extraction ability degradation due to simplifying encoders, we propose a diffusion-based model to compensate image details when decoding. Our insight is that satellite's earth observation photos are not just images but indeed multi-modal data with a nature of Text-to-Image pairing since they are collected with rich sensor data (e.g. coordinates, timestep, etc.) that can be used as the condition for diffusion generation. Extensive experiments show that COSMIC outperforms state-of-the-art baselines on both perceptual and distortion metrics.

Poster
STimage-1K4M: A histopathology image-gene expression dataset for spatial transcriptomics

Jiawen Chen, Muqing Zhou, Wenrong Wu, Jinwei Zhang, Yun Li, Didong Li

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Recent advances in multi-modal algorithms have driven and been driven by the increasing availability of large image-text datasets, leading to significant strides in various fields, including computational pathology. However, in most existing medical image-text datasets, the text typically provides high-level summaries that may not sufficiently describe sub-tile regions within a large pathology image. For example, an image might cover an extensive tissue area containing cancerous and healthy regions, but the accompanying text might only specify that this image is a cancer slide, lacking the nuanced details needed for in-depth analysis. In this study, we introduce STimage-1K4M, a novel dataset designed to bridge this gap by providing genomic features for sub-tile images. STimage-1K4M contains 1,149 images derived from spatial transcriptomics data, which captures gene expression information at the level of individual spatial spots within a pathology image. Specifically, each image in the dataset is broken down into smaller sub-image tiles, with each tile paired with $15,000-30,000$ dimensional gene expressions. With $4,293,195$ pairs of sub-tile images and gene expressions, STimage-1K4M offers unprecedented granularity, paving the way for a wide range of advanced research in multi-modal data analysis an innovative applications in computational pathology, and beyond.

Poster