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Physics-Informed ML
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VT-Intrinsic: Physics-Based Decomposition of Reflectance and Shading using a Single Visible-Thermal Image Pair
Zeqing Yuan, Mani Ramanagopal, Aswin C. Sankaranarayanan, Srinivasa G. Narasimhan
Decomposing a scene into its reflectance and shading is a challenge due to the lack of extensive ground-truth data for real-world scenes. We introduce a novel physics-based approach for intrinsic image decomposition using a pair of visible and thermal images. We leverage the principle that light not reflected from an opaque surface is absorbed and detected as heat by a thermal camera. This allows us to relate the ordinalities (or relative magnitudes) between visible and thermal image intensities to the ordinalities of shading and reflectance. The ordinalities enable dense self-supervision of an optimizing neural network to recover shading and reflectance. We perform quantitative evaluations with known reflectance and shading under natural and artificial lighting, and qualitative experiments across diverse scenes. The results demonstrate superior performance over both physics-based and recent learning-based methods, providing a path toward scalable real-world data curation with supervision.
InterPhys: Physics-aware Human Motion Synthesis in a Dynamic Scene
Chaoyue Xing*, Wei Mao, miaomiao Liu
This paper tackles the problem of physics-aware human motion synthesis in a dynamic scene. Unlike existing works which mainly tend to generate physically unrealistic motions due to limited contact modeling, typically restricted to hands, in this paper, we introduce a physics-aware human motion generation framework that explicitly models the full spectrum of human-related forces, including human-object, human-scene, and internal body dynamics. Our method imposes soft physical constraints to maintain force and torque balance, ensuring physically grounded motion synthesis. We further propose a novel continuous distance-based force model that generalizes contact modeling to arbitrary surfaces, capturing interactions not only with static environments but also with dynamic, moving objects. Extensive experiments show that our approach significantly improves physical plausibility and generalizes well to complex scenes, setting a new benchmark for physically consistent human motion generation.
Spatial-Spectral Residuals Informed Diffusion Neural Operator for Pan-sharpening
Jiahan Huang, Ran Ran, Junming Hou, Zihao Chen, Xiaofeng Cong, Junling Li, Liang-Jian Deng
Pan-sharpening, a fundamental image preprocessing technique in remote sensing, aims to generate spatially and spectrally enriched multispectral imagery by integrating complementary information from texture-rich panchromatic (PAN) images and paired low-resolution multispectral (LRMS) counterparts. Although recent generative diffusion models have achieved impressive fusion quality, these performance gains often come with substantial computational costs, rendering them impractical for resource-constrained scenarios common in remote sensing applications. This work introduces a function-space diffusion model built upon a neural operator architecture that achieves compelling performance with promising efficiency. Specifically, our framework replaces the standard attention-based denoising backbone with a Galerkin-type neural operator, significantly reducing computational complexity while maintaining excellent representational capacity. Furthermore, by explicitly integrating pixel-wise spatial-spectral consistency residuals into each reverse diffusion step, our method establishes a fine-grained, closed-loop guidance mechanism that dynamically calibrates spatial details and spectral fidelity throughout the generation process. Extensive experiments on multiple benchmark datasets demonstrate the effectiveness of our approach over state-of-the-art methods.
Learning Surgical Robotic Manipulation with 3D Spatial Priors
Yu Sheng, Lidian Wang, Xiaomeng Chu, Jiajun Deng, Min Cheng, Yanyong Zhang, Bei Hua, Houqiang Li, Jianmin Ji
Achieving 3D spatial awareness is crucial for surgical robotic manipulation, where precise and delicate operations are required. Existing methods either explicitly reconstruct the surgical scene prior to manipulation, or enhance multi-view features by adding wrist-mounted cameras to supplement the default stereo endoscopes. However, both paradigms suffer from notable limitations: the former easily leads to error accumulation and prevents end-to-end optimization due to its multi-stage nature, while the latter is rarely adopted in clinical practice since wrist-mounted cameras can interfere with the motion of surgical robot arms. In this work, we introduce the Spatial Surgical Transformer (SST), an end-to-end visuomotor policy that empowers surgical robots with 3D spatial awareness by directly exploring 3D spatial cues embedded in endoscopic images. First, we build Surgical3D, a large-scale photorealistic dataset containing 30K stereo endoscopic image pairs with accurate 3D geometry, addressing the scarcity of 3D data in surgical scenes. Based on Surgical3D, we finetune a powerful geometric transformer to extract robust 3D latent representations from stereo endoscopes images. These representations are then seamlessly aligned with the robot's action space via a lightweight multi-level spatial feature connector (MSFC), all within an endoscope-centric coordinate frame. Extensive real-robot experiments demonstrate that SST achieves state-of-the-art performance and strong spatial generalization on complex surgical tasks such as knot tying and ex-vivo organ dissection, representing a significant step toward practical clinical deployment. The dataset and code will be released.
PMRNet: Physics-informed Multi-scale Refinement Network for Medical Image Segmentation
Boce Kang
Medical image segmentation demands both high accuracy and computational efficiency, yet existing methods face a critical trade-off: CNNs lack global context while transformers incur prohibitive costs for deployment on resource-constrained devices. To address this challenge, we propose a Physics-informed Multi-scale Refinement Network (PMRNet), integrating symplectic geometry, renormalization group theory, and entropy diffusion to guide feature learning. PMRNet features three innovations: (1) a physics-informed encoder with Enhanced Symplectic Convolution for boundary detection and Renormalization Group-inspired Downsampling for information preservation; (2) a Pseudo-Global Receptive Field module achieving near-global context with linear complexity through entropy-driven diffusion; and (3) a boundary-aware decoder for precise delineation. With only 0.87M parameters and 3.43 GFLOPs, PMRNet achieves 87.25% IoU and 92.56% Dice on the challenging Clinic dataset, outperforming state-of-the-art (SOTA) models with even 100x more parameters across 12 medical imaging datasets while maintaining computational efficiency. Code is available at https://github.com/KangBoce/PMRNet.
Seeing through Light and Darkness: Sensor-Physics Grounded Deblurring HDR NeRF from Single-Exposure Images and Events
Yunshan Qi, Lin Zhu, Nan Bao, Yifan Zhao, Jia Li
Novel view synthesis from low dynamic range (LDR) blurry images, which are common in the wild, struggles to recover high dynamic range (HDR) and sharp 3D representations in extreme lighting conditions. Although existing methods employ event data to address this issue, they ignore the sensor-physics mismatches between the camera output and physical world radiance, resulting in suboptimal HDR and deblurring results. To cope with this problem, we propose a unified sensor-physics grounded NeRF framework for sharp HDR novel view synthesis from single-exposure blurry LDR images and corresponding events. We employ NeRF to directly represent the actual radiance of the 3D scene in the HDR domain and model raw HDR scene rays hitting the sensor pixels as in the physical world. A 2D pixel-wise RGB CRF model is introduced to align the NeRF rendered pixel values with the sensor-recorded LDR pixel values of the input images. A novel event CRF model is also designed to bridge the gap between physical scene dynamics and event sensor output. The two models are jointly optimized with the NeRF network, leveraging the spatial and temporal dynamic information in events to enhance the sharp HDR 3D representation learning. Experiments on the collected and public datasets demonstrate that our method achieves state-of-the-art HDR and deblurring novel view synthesis results with single-exposure blurry LDR images and corresponding events. Our code and datasets are publicly available at https://github.com/iCVTEAM/See-NeRF.
AssemblyBench: Physics-Aware Assembly of Complex Industrial Objects
Danrui Li, Jiahao Zhang, Bernhard Egger, Moitreya Chatterjee, Suhas Lohit, Tim K. Marks, Anoop Cherian
Assembling objects from parts requires understanding multimodal instructions, linking them to 3D components, and predicting physically plausible 6-DoF motions for each assembly step. Existing datasets focus on simplified scenarios, overlooking shape complexities and assembly trajectories in industrial assemblies. We introduce AssemblyBench, a synthetic dataset of 2,789 industrial objects with multimodal instruction manuals, corresponding 3D part models, and part assembly trajectories. We also propose a transformer-based model, AssemblyDyno, which uses the instructional manual and the 3D shape of each part to jointly predict assembly order and part assembly trajectories. AssemblyDyno outperforms prior works in both assembly pose estimation and trajectory feasibility, where the latter is evaluated by our physics-based simulations.
From 2D Alignment to 3D Plausibility: Unifying Heterogeneous 2D Priors and Penetration-Free Diffusion for Occlusion-Robust Two-Hand Reconstruction
Gaoge Han, Yongkang Cheng, Zhe Chen, Shaoli Huang, Tongliang Liu
Two-hand reconstruction from monocular images is hampered by complex poses and severe occlusions, which often cause interaction misalignment and two-hand penetration. We address this by decoupling the problem into 2D structural alignment and 3D spatial interaction alignment, each handled by a tailored component. For 2D alignment, we pioneer the attempt to unify heterogeneous structural priors (keypoints, segmentation, and depth) from vision foundation models as complementary structured guidance for two-hand recovery. Instead of extracting priors prediction as explicit inputs, we propose a fusion-alignment encoder that absorbs their structural knowledge implicitly, achieving foundation-level guidance without foundation-level cost. For 3D spatial alignment, we propose a two-hand penetration-free diffusion model that learns a generative mapping from interpenetrated poses to realistic, collision-free configurations. Guided by collision gradients during denoising, the model converges toward the manifold of valid two-hand interactions, preserving geometric and kinematic coherence. This generative formulation approach enables physically credible reconstructions even under occlusion or ambiguous visual input. Extensive experiments on InterHand2.6M and HIC show state-of-the-art or leading performance in interaction alignment and penetration suppression. Project: https://gaogehan.github.io/A2P/
LaDy: Lagrangian-Dynamic Informed Network for Skeleton-based Action Segmentation via Spatial-Temporal Modulation
Haoyu Ji, Xueting Liu, Yu Gao, Wenze Huang, Zhihao Yang, Weihong Ren, Zhiyong Wang, Honghai LIU
Skeleton-based Temporal Action Segmentation (STAS) aims to densely parse untrimmed skeletal sequences into frame-level action categories. However, existing methods, while proficient at capturing spatio-temporal kinematics, neglect the underlying physical dynamics that govern human motion. This oversight limits inter-class discriminability between actions with similar kinematics but distinct dynamic intents, and hinders precise boundary localization where dynamic force profiles shift. To address these, we propose the Lagrangian-Dynamic Informed Network (LaDy), a framework integrating principles of Lagrangian dynamics into the segmentation process. Specifically, LaDy first computes generalized coordinates from joint positions and then estimates Lagrangian terms under physical constraints to explicitly synthesize the generalized forces. To further ensure physical coherence, our Energy Consistency Loss enforces the work-energy theorem, aligning kinetic energy change with the work done by the net force. The learned dynamics then drive a Spatio-Temporal Modulation module: Spatially, generalized forces are fused with spatial representations to provide more discriminative semantics. Temporally, salient dynamic signals are constructed for temporal gating, thereby significantly enhancing boundary awareness. Experiments on challenging datasets show that LaDy achieves state-of-the-art performance, validating the integration of physical dynamics for action segmentation. Code is available at https://github.com/HaoyuJi/LaDy.
UniPixie: Unified and Probabilistic 3D Physics Learning via Flow Matching
Qilin Huang, Quynh Anh Huynh, Long Le, Chen Wang, Chuhao Chen, Ryan Lucas, ERIC EATON, Lingjie Liu
Existing feed-forward networks excel at predicting a single set of physical properties from visual appearance, but this point-estimate paradigm fundamentally fails to capture the real world's inherent physical ambiguity. We address this by reframing physics prediction as a task of learning a controllable, continuous distribution of material properties. We introduce UNIPIXIE, a framework trained to predict a continuous and parameterized path of physically plausible material properties from a single visual input. By learning a direct mapping along an object's softest-to-stiffest spectrum on our PIXIEMULTIVERSE dataset, UNIPIXIE allows for controllable generation of diverse, physically-valid material fields via a single intuitive parameter. Crucially, UNIPIXIE introduces a novel unified architecture to produce simulation-ready parameters for diverse physics solvers, including continuum-based Material Point Method (MPM), reduced-order deformation based on Linear Blend Skinning (LBS), and anchor-based Spring-Mass systems, addressing a key portability issue in prior work. Experiments show our approach not only generates a rich variety of plausible dynamics but also reduces Young's Modulus prediction error by over 50% against the strongest deterministic baseline, bridging the gap between static point-estimates and the continuous nature of physical reality.
MicroFM: Physics-guided Flow Matching for Isotropic Microscopy Reconstruction
Xingzu Zhan, Runmin Jiang, Vatsal Gupta, Tanush Swaminathan, Yanwen Wang, Genpei Zhang, Haili Wang, Min Xu
Isotropic microscopy reconstruction remains challenging because the anisotropic point spread function in optical systems yields much poorer axial resolution and hampers accurate 3D analysis. Hardware strategies can approach isotropy, yet they are complex, costly, susceptible to sidelobes, and introduce phototoxicity. Deep learning approaches reduce acquisition burden, yet synthetic pipelines often rely on Gaussian blur mismatched to physical degradation, and many methods lack explicit volumetric geometry constraints as they process 2D slices independently, resulting in low-fidelity reconstructions. To address these challenges, we present MicroFM, which synthesizes realistic training data using physical PSFs matched to the target microscope. MicroFM also introduces a physics-guided flow-matching framework for isotropic microscopy reconstruction, guided by a continuous implicit geometry prior to achieve high-fidelity isotropic recovery. Across four fluorescence microscopy systems and datasets, MicroFM achieves state-of-the-art (SOTA) performance, producing sharper structures, more isotropic spectra, and substantial gains in both full-reference and no-reference metrics.
A Geometric Algebra-Informed 3DGS Framework for Wireless Channel Prediction
Jingzhou Shen, Tianya Zhao, Xuyu Wang
In this paper, we introduce Geometric Algebra-Informed 3D Gaussian Splatting (GAI-GS), a framework for wireless modeling that couples 3D Gaussian splatting with a geometric algebra-based attention mechanism to explicitly model ray-object interactions in complex propagation environments. GAI-GS encodes joint spatial-electromagnetic (EM) relations into token representations, enabling scene-level aggregation within a unified, end-to-end neural architecture. This design grounds wireless ray propagation in electromagnetic principles, allowing token interactions to model key effects such as multipath, attenuation, and reflection/diffraction. Through extensive evaluations on multiple real-world indoor datasets, GAI-GS consistently surpasses current baselines across various wireless tasks.
WiseEdit: Benchmarking Cognition- and Creativity-Informed Image Editing
Kaihang Pan, Weile Chen, Haiyi Qiu, Qifan Yu, Wendong Bu, Zehan Wang, Yun Zhu, Juncheng Li, Siliang Tang
Recent image editing models boast next-level intelligent capabilities, facilitating cognition- and creativity-informed image editing. Yet, existing benchmarks provide too narrow a scope for evaluation, failing to holistically assess these advanced abilities. To address this, we introduce WiseEdit, a knowledge-intensive benchmark for comprehensive evaluation of cognition- and creativity-informed image editing, featuring deep task depth and broad knowledge breadth. Drawing an analogy to human cognitive creation, WiseEdit decomposes image editing into three cascaded steps--Awareness, Interpretation, and Imagination--each corresponding to a task that poses a challenge for models to complete at the specific step. It also encompasses complex tasks, where none of the three steps can be finished easily. Furthermore, WiseEdit incorporates three fundamental types of knowledge: Declarative, Procedural, and Metacognitive knowledge. Ultimately, WiseEdit comprises 1,220 test cases, objectively revealing the limitations of SoTA image editing models in knowledge-based cognitive reasoning and creative composition capabilities.
Dynamic Black-hole Emission Tomography with Physics-informed Neural Fields
Berthy T. Feng, Andrew A. Chael, David Bromley, Aviad Levis, William T. Freeman, Katherine L. Bouman
With the success of static black-hole imaging, the next frontier is the dynamic and 3D imaging of black holes. Recovering the dynamic 3D gas near a black hole would reveal previously-unseen parts of the universe and inform new physics models. However, only sparse radio measurements from a single viewpoint are possible, making the dynamic 3D reconstruction problem significantly ill-posed. Previously, BH-NeRF addressed the ill-posed problem by assuming Keplerian dynamics of the gas, but this assumption breaks down near the black hole, where the strong gravitational pull of the black hole and increased electromagnetic activity complicate fluid dynamics. To overcome the restrictive assumptions of BH-NeRF, we propose PI-DEF, a physics-informed approach that uses differentiable neural rendering to fit a 4D (time + 3D) emissivity field given EHT measurements. Our approach jointly reconstructs the 3D velocity field with the 4D emissivity field and enforces the velocity as a soft constraint on the dynamics of the emissivity. In experiments on simulated data, we find significantly improved reconstruction accuracy over both BH-NeRF and a physics-agnostic approach. We demonstrate how our method may be used to estimate other physics parameters of the black hole, such as its spin.
Cell-Type Prototype-Informed Neural Network for Gene Expression Estimation from Pathology Images
Kazuya Nishimura, Ryoma Bise, Shinnosuke Matsuo, Haruka Hirose, Yasuhiro Kojima
Estimating slide- and patch-level gene expression profiles from pathology images enables rapid and low-cost molecular analysis with broad clinical impact. Despite strong results, existing approaches treat gene expression as a mere slide- or spot-level signal and do not incorporate the fact that the measured expression arises from the aggregation of underlying cell-level expression. To explicitly introduce this missing cell-resolved guidance, we propose a Cell-type Prototype-informed Neural Network (CPNN) that leverages publicly available single-cell RNA-sequencing datasets. Since single-cell measurements are noisy and not paired with histology images, we first estimate cell-type prototypes--mean expression profiles that capture stable gene-gene co-variation patterns. CPNN then learns cell-type compositional weights directly from images and models the relationship between prototypes and observed bulk or spatial expression, providing a biologically grounded and structurally regularized prediction framework. We evaluate CPNN on three slide-level datasets and three patch-level spatial transcriptomics datasets. Across all settings, CPNN achieves the highest performance in terms of Spearman correlation. Moreover, by visualizing the inferred compositional weights, our framework provides interpretable insights into which cell types drive the predicted expression.Code is publicly available at https://github.com/naivete5656/CPNN.
Physics-Guided Multistep Deformation Reversal for Ancient Bamboo Slip Restoration
Qianqian Tang, Jinchi Zhu, Xiaolu Zhou, Yongchao Xu
Bamboo slips are essential media for recording ancient East Asian civilizations, but excavated slips often suffer severe deformation due to dehydration and stress effects, creating substantial challenges for restoration. Traditional manual restoration is time-consuming and risks damage, while existing generative models struggle with the complex non-linear deformations in bamboo materials.We propose a novel framework for inverse restoration of deformed bamboo slips that provides a progressive physical deformation modeling with stepwise inverse displacement prediction. Our approach establishes a computable mathematical model of deformation based on wood fiber microstructure and stress-diffusion coupling effects, enabling the forward process to simulate physically plausible deformation trajectories as a deterministic, physics-driven progressive evolution. The inverse process transforms from predicting abstract noise to learning physically meaningful inverse displacement fields that progressively restore deformations.Experimental results show substantial gains in restoration fidelity while preserving delicate textual features, enabling the reliable correction of complex non-linear deformations that defeat traditional techniques. By integrating physical insights into bamboo material behavior with progressive restoration modeling, this work establishes a new paradigm for digital archaeological restoration--one that holds significant potential to transform how deformed cultural relics are reconstructed and studied. Code is available at https://github.com/VillanelleQQ/PGDR-BambooSlips
Physics-Consistent Diffusion for Efficient Fluid Super-Resolution via Multiscale Residual Correction
Zhihao Li, Shengwei Dong, Chuang Yi, Junxuan Gao, Zhilu Lai, Zhiqiang Liu, Wei Wang, Guangtao Zhang
Existing image SR and generic diffusion models transfer poorly to fluid SR: they are sampling-intensive, ignore physical constraints, and often yield spectral mismatch and spurious divergence. We address fluid super-resolution (SR) with **ReMD** (**Re**sidual-**M**ultigrid **D**iffusion), a physics-consistent diffusion framework. At each reverse step, ReMD performs a **multigrid residual correction**: the update direction is obtained by coupling data consistency with lightweight physics cues and then correcting the residual across scales; the multiscale hierarchy is instantiated with a **multi-wavelet** basis to capture both large structures and fine vortical details. This coarse-to-fine design accelerates convergence and preserves fine structures while remaining equation-free. Across atmospheric and oceanic benchmarks, ReMD improves accuracy and spectral fidelity, reduces divergence, and reaches comparable quality with markedly fewer sampling steps than diffusion baselines. Our results show that enforcing physics consistency **inside** the diffusion process via multigrid residual correction and multi-wavelet multiscale modeling is an effective route to efficient fluid SR.
AviaSafe: A Physics-Informed Data-Driven Model for Aviation Safety-Critical Cloud Forecasts
Zijian Zhu, Qiusheng Huang, Anboyu Guo, Xiaohui Zhong, Hao Li
Current AI weather forecasting models predict conventional atmospheric variables but cannot distinguish between cloud microphysical species critical for aviation safety. We introduce AviaSafe, a hierarchical, physics-informed neural forecaster that produces global, six-hourly predictions of these four hydrometeor species for lead times up to 7 days. Our approach addresses the unique challenges of cloud prediction: extreme sparsity, discontinuous distributions, and complex microphysical interactions between species. We integrate the Icing Condition (IC) index from aviation meteorology as a physics-based constraint that identifies regions where supercooled water fuels explosive ice crystal growth. The model employs a hierarchical architecture that first predicts cloud spatial distribution through masked attention, then quantifies species concentrations within identified regions. Training on ERA5 reanalysis data, our model achieves lower RMSE for cloud species compared to baseline and outperforms operational numerical models on certain key variables at 7-day lead times.The ability to forecast individual cloud species enables new applications in aviation route optimization where distinguishing between ice and liquid water determines engine icing risk.
AnchorSplat: Feed-Forward 3D Gaussian Splatting With 3D Geometric Priors
Xiaoxue Zhang, Xiaoxu Zheng, Yixuan Yin, Tiao Zhao, Kaihua Tang, Michael Bi Mi, Zhan Xu, Dave Zhenyu Chen
Recent feed-forward Gaussian reconstruction models adopt a pixel-aligned formulation that maps each 2D pixel to a 3D Gaussian, entangling Gaussian representations tightly with the input images. In this paper, we propose AnchorSplat, a novel feed-forward 3DGS framework for scene-level reconstruction that represents the scene directly in 3D space. AnchorSplat introduces an anchor-aligned Gaussian representation guided by 3D geometric priors (e.g., sparse point clouds, voxels, or RGB-D point clouds), enabling a more geometry-aware renderable 3D Gaussians that is independent of image resolution and number of views. This design substantially reduces the number of required Gaussians, improving computational efficiency while enhancing reconstruction fidelity. Beyond the anchor-aligned design, we utilize a Gaussian Refiner to adjust the intermediate Gaussians via merely a few forward passes. Experiments on the ScanNet++ v2 NVS benchmark demonstrate the SOTA performance, outperforming previous methods with more view-consistent and substantially fewer Gaussian primitives.
Domain Sensitive Federated Learning with Fisher-Informed Pruning
Chenchen Lin, Wenhao Yuan, Zhengji Xu, Xuehe Wang
Federated Learning (FL) serves as a prominent distributed training paradigm, enabling devices to collaboratively train a shared model with local data. However, in practice, clients generally possess data from multiple distributional domains, posing significant challenges to efficiency and generalization. In this paper, we propose a domain-sensitive federated pruning framework, FedFIP, that preserves domain-invariant structures while retaining domain-specific representations. The Domain-Sensitive Fisher Pruning (DSFP) module estimates channel importance per domain via Fisher information, and uploads this signal to the server to obtain a globally shared pruning mask. Given local domain heterogeneity, each client reuses its Fisher information to selectively reactivate domain-specific channels, yielding personalized sparse models that remain structurally aligned yet adapt to local heterogeneity. To further enhance performance, we adopt a Domain-Sensitive Regularization (DSR) module: the server builds domain prototypes from uploaded importance signals and broadcasts them back. Guided by the domain prototypes, we adopt a structure-contrastive loss to strengthen intra-domain consistency and inter-domain discriminability. We propose a structure-aware aggregation algorithm that fuses heterogeneous personalized architectures into a domain-generalized global model. Experiments on multi-domain benchmarks demonstrate that FedFIP surpasses state-of-the-art FL baselines while substantially shrinking model size.