CVPR 2025 Papers

Subtomogram alignment is a critical task in cryo-electron tomography (cryo-ET) analysis, essential for achieving high-resolution reconstructions of macromolecular complexes. However, learning effective positional representations remains challenging due to limited labels and high noise levels inherent in cryo-ET data. In this work, we address this challenge by proposing a self-supervised learning approach that leverages intrinsic geometric transformations as implicit supervisory signals, enabling robust representation learning despite data scarcity. We introduce BOE-ViT, the first Vision Transformer (ViT) framework for 3D subtomogram alignment. Recognizing that traditional ViTs lack equivariance and are therefore suboptimal for orientation estimation, we enhance the model with two innovative modules that introduce equivariance include 1) the Polyshift module for improved shift estimation and 2) Multi-Axis Rotation Encoding (MARE) for enhanced rotation estimation. Experimental results demonstrate that BOE-ViT significantly outperforms state-of-the-art methods. Notably, at SNR 0.01 dataset, our approach achieves a 77.3% reduction in rotation estimation error and a 62.5% reduction in translation estimation error, effectively overcoming the challenges in cryo-ET subtomogram alignment.

Hyperspectral images (HSI) densely sample the world in both the space and frequency domains and, therefore, are more distinctive than RGB images. Usually, HSI needs to be calibrated to minimize the impact of various illumination conditions. The traditional way to calibrate HSI utilizes a physical reference, which involves manual operations, occlusions, and/or limits camera mobility. These limitations inspire this paper to automatically calibrate HSIs using a learning-based method. Towards this goal, a large-scale HSI calibration dataset, which has 765 high-quality HSI pairs covering diversified natural scenes and illuminations, is created. The dataset is further expanded to 7650 pairs by combining with 10 different physically measured illuminations. A spectral illumination transformer (SIT) together with an illumination attention module is proposed. Extensive benchmarks demonstrate the SoTA performance of the proposed SIT. The benchmarks also indicate that low-light conditions are more challenging than normal conditions. The dataset and codes are available online: https://github.com/duranze/Automatic-spectral-calibration-of-HSI.

Structured pruning and quantization are fundamental techniques used to reduce the size of deep neural networks (DNNs) and typically are applied independently. Applying these techniques jointly via co-optimization has the potential to produce smaller, high-quality models. However, existing joint schemes are not widely used because of (1) engineering difficulties (complicated multi-stage processes), (2) black-box optimization (extensive hyperparameter tuning to control the overall compression), and (3) insufficient architecture generalization. To address these limitations, we present the framework GETA, which automatically and efficiently performs joint structured pruning and quantization-aware training on any DNN. GETA introduces three key innovations: (I) a quantization-aware dependency graph (QADG) that constructs a pruning search space for generic quantization-aware DNN, (II) a partially projected stochastic gradient method that guarantees layer-wise bit constraints are satisfied, and (III) a new joint learning strategy that incorporates interpretable relationships between pruning and quantization. We present numerical experiments on both convolutional neural networks and transformer architectures that show that our approach achieves competitive (often superior) performance compared to existing joint pruning and quantization methods. The source code is available at https://github.com/microsoft/GETA.

Integrating frames and events has become a widely accepted solution for various tasks in challenging scenarios. However, most multimodal methods directly convert events into image-like formats synchronized with frames and process each stream through separate two-branch backbones, making it difficult to fully exploit the spatiotemporal events while limiting inference frequency to the frame rate. To address these problems, we propose a novel asynchronous collaborative graph representation, namely ACGR, which is the first trial to explore a unified graph framework for asynchronously processing frames and events with high performance and low latency. Technically, we first construct unimodal graphs for frames and events to preserve their spatiotemporal properties and sparsity. Then, an asynchronous collaborative alignment module is designed to align and fuse frames and events into a unified graph and the ACGR is generated through graph convolutional networks. Finally, we innovatively introduce domain adaptation to enable cross-modal interactions between frames and events by aligning their feature spaces. Experimental results show that our approach outperforms state-of-the-art methods in both object detection and depth estimation tasks, while significantly reducing computational latency and achieving real-time inference up to 200 Hz. Our code can be available at https://github.com/dianzl/ACGR.

Estimating camera motion and intrinsics from casual videos is a core challenge in computer vision. Traditional bundle-adjustment based methods, such as SfM and SLAM, struggle to perform reliably on arbitrary data. Although specialized SfM approaches have been developed for handling dynamic scenes, they either require intrinsics or computationally expensive test-time optimization and often fall short in performance. Recently, methods like Dust3r have reformulated the SfM problem in a more data-driven way. While such techniques show promising results, they are still 1) not robust towards dynamic objects and 2) require labeled data for supervised training. As an alternative, we propose AnyCam, a fast transformer model that directly estimates camera poses and intrinsics from a dynamic video sequence in feed-forward fashion. Our intuition is that such a network can learn strong priors over realistic camera poses. To scale up our training, we rely on an uncertainty-based loss formulation and pre-trained depth and flow networks instead of motion or trajectory supervision. This allows us to use diverse, unlabelled video datasets obtained mostly from YouTube. Additionally, we ensure that the predicted trajectory does not accumulate drift over time through a lightweight trajectory refinement step. We test AnyCam on established datasets, where it delivers accurate camera poses and intrinsics both qualitatively and quantitatively. Furthermore, even with trajectory refinement, AnyCam is significantly faster than existing works for SfM in dynamic settings. Finally, by combining camera information, uncertainty, and depth, our model can produce high-quality 4D pointclouds. For more details and code, please check out our project page: https://fwmb.github.io/anycam

We introduce Any6D, a model-free framework for 6D object pose estimation that requires only a single RGB-D anchor image to estimate both the 6D pose and size of unknown objects in novel scenes. Unlike existing methods that rely on textured 3D models or multiple viewpoints, Any6D leverages a joint object alignment process to enhance 2D-3D alignment and metric scale estimation for improved pose accuracy. Our approach integrates a render-and-compare strategy to generate and refine pose hypotheses, enabling robust performance in scenarios with occlusions, non-overlapping views, diverse lighting conditions, and large cross-environment variations. We evaluate our method on five challenging datasets: REAL275, Toyota-Light, HO3D, YCBINEOAT, and LM-O, demonstrating its effectiveness in significantly outperforming state-of-the-art methods for novel object pose estimation. Project page: https://taeyeop.com/any6d

Large Vision-Language Models (LVLMs) have achieved impressive results across various cross-modal tasks. However, hallucinations, i.e., the models generating counterfactual responses, remain a challenge. Though recent studies have attempted to alleviate object perception hallucinations, they focus on the models' response generation, and overlook the task question itself. This paper discusses the vulnerability of LVLMs in solving counterfactual presupposition questions (CPQs), where the models are prone to accept the presuppositions of counterfactual objects and produce severe hallucinatory responses. To this end, we introduce "Antidote", a unified, synthetic data-driven post-training framework for mitigating both types of hallucination above. It leverages synthetic data to incorporate factual priors into questions to achieve self-correction, and decouples the mitigation process into a preference optimization problem. Furthermore, we construct "CP-Bench", a novel benchmark to evaluate LVLMs' ability to correctly handle CPQs and produce factual responses. Applied to the LLaVA series, Antidote can simultaneously enhance performance on CP-Bench by over 50%, POPE by 1.8-3.3%, and CHAIR & SHR by 30-50%, all without relying on external supervision from stronger LVLMs or human feedback and without introducing noticeable catastrophic forgetting issues.

Medical Visual Question Answering (Med-VQA) is a challenging task that requires a deep understanding of both medical images and textual questions. Although recent works leveraging Medical Vision-Language Pre-training (Med-VLP) have shown strong performance on the Med-VQA task, there is still no unified solution for modality alignment, and the issue of hard negatives remains under-explored. Additionally, commonly used knowledge fusion techniques for Med-VQA may introduce irrelevant information. In this work, we propose a framework to address these challenges through three key contributions: (1) a unified solution for heterogeneous modality alignments across multiple levels, modalities, views, and stages, leveraging methods such as contrastive learning and optimal transport theory; (2) a hard negative mining method that employs soft labels for multi-modality alignments and enforces the hard negative pair discrimination; and (3) a Gated Cross-Attention Module for Med-VQA that integrates the answer vocabulary as prior knowledge and select relevant information from it. Our framework outperforms the previous state-of-the-art on widely used Med-VQA datasets like RAD-VQA, SLAKE, PathVQA and VQA-2019. The code will be publicly available.

Cross-modal alignment is crucial for multimodal representation fusion due to the inherent heterogeneity between modalities. While Transformer-based methods have shown promising results in modeling inter-modal relationships, their quadratic computational complexity limits their applicability to long-sequence or large-scale data. Although recent Mamba-based approaches achieve linear complexity, their sequential scanning mechanism poses fundamental challenges in comprehensively modeling cross-modal relationships. To address this limitation, we propose AlignMamba, an efficient and effective method for multimodal fusion. Specifically, grounded in Optimal Transport, we introduce a local cross-modal alignment module that explicitly learns token-level correspondences between different modalities. Moreover, we propose a global cross-modal alignment loss based on Maximum Mean Discrepancy to implicitly enforce the consistency between different modal distributions. Finally, the unimodal representations after local and global alignment are passed to the Mamba backbone for further cross-modal interaction and multimodal fusion. Extensive experiments on complete and incomplete multimodal fusion tasks demonstrate the effectiveness and efficiency of the proposed method. For instance, on the CMU-MOSI dataset, AlignMamba improves classification accuracy by 0.9%, reduces GPU memory usage by 20.3%, and decreases inference time by 83.3%.

Generating visually appealing images is fundamental to modern text-to-image generation models. A potential solution to better aesthetics is direct preference optimization (DPO), which has been applied to diffusion models to improve general image quality including prompt alignment and aesthetics. Popular DPO methods propagate preference labels from clean image pairs to all the intermediate steps along the two generation trajectories. However, preference labels provided in existing datasets are blended with layout and aesthetic opinions, which would disagree with aesthetic preference. Even if aesthetic labels were provided (at substantial cost), it would be hard for the two-trajectory methods to capture nuanced visual differences at different steps. To improve aesthetics economically, this paper uses existing generic preference data and introduces step-by-step preference optimization (SPO) that discards the propagation strategy and allows fine-grained image details to be assessed. Specifically, at each denoising step, we 1) sample a pool of candidates by denoising from a shared noise latent, 2) use a step-aware preference model to find a suitable win-lose pair to supervise the diffusion model, and 3) randomly select one from the pool to initialize the next denoising step. This strategy ensures that diffusion models focus on the subtle, fine-grained visual differences instead of layout aspect. We find that aesthetics can be significantly enhanced by accumulating these improved minor differences. When fine-tuning Stable Diffusion v1.5 and SDXL, SPO yields significant improvements in aesthetics compared with existing DPO methods while not sacrificing image-text alignment compared with vanilla models. Moreover, SPO converges much faster than DPO methods due to the use of more correct preference labels provided by the step-aware preference model. Code and models are available at https://github.com/RockeyCoss/SPO.

Visual layouts are essential in graphic design fields such as advertising, posters, and web interfaces. The application of generative models for content-aware layout generation has recently gained traction. However, these models fail to understand the contextual aesthetic requirements of layout design and do not align with human-like preferences, primarily treating it as a prediction task without considering the final rendered output. To overcome these problems, we offer Aesthetic-Aware Preference Alignment (AAPA), a novel technique to train a Multi-modal Large Language Model (MLLM) for layout prediction that uses MLLM's aesthetic preferences for Direct Preference Optimization over graphic layouts. We propose a data filtering protocol utilizing our layout-quality heuristics for AAPA to ensure training happens on high-quality layouts. Additionally, we introduce a novel evaluation metric that uses another MLLM to compute the win rate of the generated layout against the ground-truth layout based on aesthetics criteria. We also demonstrate the applicability of AAPA for MLLMs of varying scales (1B to 8B parameters) and LLM families (Qwen, Phi, InternLM). By conducting thorough qualitative and quantitative analyses, we verify the efficacy of our approach on two challenging benchmarks - Crello and Webui, showcasing 17%, and 16% improvement over current State-of-The-Art methods, thereby highlighting the potential of MLLMs in aesthetic-aware layout generation.

We propose the first 4D tracking and mapping method that jointly performs camera localization and non-rigid surface reconstruction via differentiable rendering. Our approach captures 4D scenes from an online stream of color images with depth measurements or predictions by simultaneously optimizing scene geometry, appearance, dynamics, and camera ego-motion. Although natural environments exhibit complex non-rigid motions, 4D-SLAM remains relatively underexplored due to its inherent challenges; even with 2.5D signals, the problem is ill-posed because of the high dimensionality of the optimization space. To overcome these challenges, we first introduce a SLAM method based on Gaussian surface primitives that leverages depth signals more effectively than 3D Gaussians, thereby achieving accurate surface reconstruction. To further model non-rigid deformations, we employ a warp-field represented by a multi-layer perceptron (MLP) and introduce a novel camera pose estimation technique along with surface regularization terms that facilitate spatio-temporal reconstruction. In addition to these algorithmic challenges, a significant hurdle in 4D-SLAM research is the lack of publicly available datasets with reliable ground truth and evaluation protocols. To address this, we present a novel synthetic dataset of everyday objects with diverse motions, leveraging large-scale object models and animation modeling. In summary, we open up the modern 4D-SLAM research by introducing a novel method and evaluation protocols grounded in modern vision and rendering techniques.